Mycobacterium genavense in the Netherlands: an opportunistic pathogen in HIV and non-HIV immunocompromised patients. An observational study in 14 cases

Autor: Martin J. Boeree, Edgar J G Peters, J. van Ingen, Cecile Magis-Escurra, P.N.R. Dekhuijzen, D. van Soolingen, Wouter Hoefsloot

Publikováno v: Hoefsloot, W, van Ingen, J, Peters, E J G, Magis-Escurra, C, Dekhuijzen, P N R, Boeree, M J & van Soolingen, D 2013, ' Mycobacterium genavense in the Netherlands: an opportunistic pathogen in HIV and non-HIV immunocompromised patients. An observational study in 14 cases ', Clinical Microbiology and Infection, vol. 19, no. 5, pp. 432-437 . https://doi.org/10.1111/j.1469-0691.2012.03817.x
Clinical Microbiology and Infection, 19, 5, pp. 432-7
Clinical Microbiology and Infection, 19(5), 432-437
Clinical Microbiology and Infection, 19, 432-7

Item does not contain fulltext Mycobacterium genavense is an opportunistic non-tuberculous mycobacterium previously mostly associated with HIV-infected patients with CD4 counts below 100/muL. In this retrospective observational study of medical chart

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::421a397a66b7473ed5247c5b21071ddf

Controlled Human Malaria Infections by Intradermal Injection of Cryopreserved Plasmodium falciparum Sporozoites

Autor: Soundarapandian Velmurugan, Peter F. Billingsley, André J. A. M. van der Ven, Else M. Bijker, Stephen L. Hoffman, Theo Arens, Robert W. Sauerwein, Sumana Chakravarty, Eric R. James, Anne C. Teirlinck, Anusha Gunasekera, Meta Roestenberg, Cornelus C. Hermsen, Karina Teelen, Anja Scholzen, B. Kim Lee Sim, Guido J. H. Bastiaens

Publikováno v: The American Journal of Tropical Medicine and Hygiene
American Journal of Tropical Medicine and Hygiene, 88, 1, pp. 5-13
American Journal of Tropical Medicine and Hygiene, 88, 5-13

Controlled human malaria infection with sporozoites is a standardized and powerful tool for evaluation of malaria vaccine and drug efficacy but so far only applied by exposure to bites of Plasmodium falciparum (Pf)-infected mosquitoes. We assessed in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f023c2840557c11fc92e2fba999086e6
https://doi.org/10.4269/ajtmh.2012.12-0613

Evaluation of co-trimoxazole in the treatment of multidrug-resistant tuberculosis

Autor: Jos G. W. Kosterink, Noor Alsaad, Dick van Soolingen, Wiel C M de Lange, Arianna D. Pranger, Jan-Willem C. Alffenaar, Richard van Altena, Tjip S. van der Werf

Publikováno v: European Respiratory Journal, 42, 504-12
European Respiratory Journal, 42, 2, pp. 504-12
European Respiratory Journal, 42(2), 504-512. EUROPEAN RESPIRATORY SOC JOURNALS LTD

Item does not contain fulltext Co-trimoxazole (SXT), a combination of sulfamethoxazole and trimethoprim, has shown in vitro activity against Mycobacterium tuberculosis. However, the pharmacokinetic and pharmacodynamic parameters of SXT in multidrug-r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::219ea2b23c0d7a172e89d4b3f6f91e80
https://doi.org/10.1183/09031936.00114812

A novel, broad-spectrum inhibitor of enterovirus replication that targets host cell factor phosphatidylinositol 4-kinase IIIβ

Autor: van der Schaar, H.M., Leyssen, Pieter, Thibaut, H.J., de Palma, Armando, van der Linden, Lonneke, Lanke, Kjerstin H.W., Lacroix, Céline, Verbeken, Erik, Conrath, Katja, Macleod, Angus M, Mitchell, Dale R, Palmer, Nicholas J, van de Poël, Hervé, Andrews, Martin, Neyts, Johan, van Kuppeveld, F.J.M., Strategic Infection Biology, Dep Infectieziekten Immunologie, I&I SIB1

Publikováno v: Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, 57, 4971-81
Antimicrobial Agents and Chemotherapy, 57(10), 4971. American Society for Microbiology
Antimicrobial Agents and Chemotherapy, 57, pp. 4971-81

Despite their high clinical and socioeconomic impacts, there is currently no approved antiviral therapy for the prophylaxis or treatment of enterovirus infections. Here we report on a novel inhibitor of enterovirus replication, compound 1, 2-fluoro-4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92056fbcc9ddfa78b77d3d2c1b17446e
https://hdl.handle.net/2066/127282

Consequences of Noncompliance for Therapy Efficacy and Emergence of Resistance in Murine Tuberculosis Caused by the Beijing Genotype of Mycobacterium tuberculosis

Autor: Henri A. Verbrugh, Marian T. ten Kate, Jurriaan E. M. de Steenwinkel, Gerjo J. de Knegt, Martin J. Boeree, Rob E. Aarnoutse, Irma A. J. M. Bakker-Woudenberg, Michael A. den Bakker, Dick van Soolingen

Publikováno v: Antimicrobial Agents & Chemotherapy, 56(9), 4937-4944. American Society for Microbiology
Antimicrobial Agents and Chemotherapy, 56, 4937-44
Antimicrobial Agents and Chemotherapy, 56, 9, pp. 4937-44

Despite great effort by health organizations worldwide in fighting tuberculosis (TB), morbidity and mortality are not declining as expected. One of the reasons is related to the evolutionary development of Mycobacterium tuberculosis , in particular t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af144a579a3ca362bcf556490a062eb5
https://doi.org/10.1128/aac.00124-12