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pro vyhledávání: '"Pouya Azizi"'
Autor:
Marco A. Ciufolini, Simon Law, Dieter Brömme, Pouya Azizi, Andrew Jamroz, Preety Panwar, Dongwei Zhang
Publikováno v:
British Journal of Pharmacology. 175:902-923
BACKGROUND AND PURPOSE Attempts to generate active site-directed cathepsin K (CatK) inhibitors for the treatment of osteoporosis have failed because of side effects. We have previously shown that an ectosteric tanshinone CatK inhibitor isolated from
Autor:
Georgina S. Butler, Preety Panwar, Pouya Azizi, Christopher M. Overall, Dieter Brömme, Andrew Jamroz
Publikováno v:
Matrix biology : journal of the International Society for Matrix Biology. 65
The natural aging process and various pathologies correlate with alterations in the composition and the structural and mechanical integrity of the connective tissue. Collagens represent the most abundant matrix proteins and provide for the overall st