Synthesis of novel aryl-substituted 2-aminopyridine derivatives by the cascade reaction of 1,1-enediamines with vinamidinium salts to develop novel anti-Alzheimer agents.

Autor: Loori, Sama¹ (AUTHOR), Pourtaher, Hormoz¹ (AUTHOR), Mehranpour, Abdolmohammad¹ (AUTHOR) ammehranpour@hotmail.com, Hasaninejad, Alireza¹ (AUTHOR), Eftekharian, Mohammadreza² (AUTHOR), Iraji, Aida^3,4 (AUTHOR) iraji@sums.ac.ir

Publikováno v: Scientific Reports. 6/14/2024, Vol. 14 Issue 1, p1-21. 21p.

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Highly efficient, catalyst-free, one-pot sequential four-component synthesis of novel spiroindolinone-pyrazole scaffolds as anti-Alzheimer agents: in silico study and biological screening.

Autor: Pourtaher, Hormoz, Mohammadi, Yasaman, Hasaninejad, Alireza, Iraji, Aida

Publikováno v: RSC Medicinal Chemistry; Jan2024, Vol. 15 Issue 1, p207-222, 16p

Highly efficient, catalyst-free, one-pot sequential four-component synthesis of novel spiroindolinone-pyrazole scaffolds as anti-Alzheimer agents: in silico study and biological screening.

Autor: Pourtaher H; Department of Chemistry, Faculty of Sciences, Persian Gulf University Bushehr Iran alirezahasaninejad@gmail.com a_hasaninejad@yahoo.com., Mohammadi Y; Research Center for Traditional Medicine and History of Medicine, Department of Persian Medicine, School of Medicine, Shiraz University of Medical Sciences Shiraz 7134845794 Iran aida.iraji@gmail.com iraji@sums.ac.ir.; Stem Cells Technology Research Center, Shiraz University of Medical Sciences Shiraz Iran., Hasaninejad A; Department of Chemistry, Faculty of Sciences, Persian Gulf University Bushehr Iran alirezahasaninejad@gmail.com a_hasaninejad@yahoo.com., Iraji A; Research Center for Traditional Medicine and History of Medicine, Department of Persian Medicine, School of Medicine, Shiraz University of Medical Sciences Shiraz 7134845794 Iran aida.iraji@gmail.com iraji@sums.ac.ir.; Stem Cells Technology Research Center, Shiraz University of Medical Sciences Shiraz Iran.

Publikováno v: RSC medicinal chemistry [RSC Med Chem] 2023 Dec 04; Vol. 15 (1), pp. 207-222. Date of Electronic Publication: 2023 Dec 04 (Print Publication: 2024).