Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Pouria, Mashouri"'
Autor:
Sergey Protserov, Jaryd Hunter, Haochi Zhang, Pouria Mashouri, Caterina Masino, Michael Brudno, Amin Madani
Publikováno v:
npj Digital Medicine, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Deep learning for computer vision can be leveraged for interpreting surgical scenes and providing surgeons with real-time guidance to avoid complications. However, neither generalizability nor scalability of computer-vision-based surgical gu
Externí odkaz:
https://doaj.org/article/7a8093a70f654890985e8f6181bc5bd4
Autor:
Victor H Ferreira, Andrzej Chruscinski, Vathany Kulasingam, Trevor J Pugh, Tamara Dus, Brad Wouters, Amit Oza, Matthew Ierullo, Terrance Ku, Beata Majchrzak-Kita, Sonika T Humar, Ilona Bahinskaya, Natalia Pinzon, Jianhua Zhang, Lawrence E Heisler, Paul M Krzyzanowski, Bernard Lam, Ilinca M Lungu, Dorin Manase, Krista M Pace, Pouria Mashouri, Michael Brudno, Michael Garrels, Tony Mazzulli, Myron Cybulsky, Atul Humar, Deepali Kumar
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0247258 (2021)
Health care workers (HCWs) are at higher risk for SARS-CoV-2 infection and may play a role in transmitting the infection to vulnerable patients and members of the community. This is particularly worrisome in the context of asymptomatic infection. We
Externí odkaz:
https://doaj.org/article/296e0a64cbd94bcf97642f459073385f
Autor:
Tugce B. Balci, Michael Brudno, Willie H. Chang, Annie Olry, Peter N. Robinson, Sylvie Maiella, Brittney Johnstone, Mia Husić, Sarah L. Sawyer, Pouria Mashouri, Alexander X. Lozano, Ana Rath
Publikováno v:
Genetics in Medicine. 22:1391-1400
Purpose Computational documentation of genetic disorders is highly relianton structured data for differential diagnosis, pathogenic variant identification, and patient matchmaking. However, most information on rare diseases (RDs) exists in free form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd91cdfd0cb1dfa117fbd8d0ffcc4347
https://doi.org/10.1038/s41436-020-0812-7
https://doi.org/10.1038/s41436-020-0812-7
Autor:
Hannah G, Driver, Taila, Hartley, E Magda, Price, Andrei L, Turinsky, Orion J, Buske, Matthew, Osmond, Arun K, Ramani, Emily, Kirby, Kristin D, Kernohan, Madeline, Couse, Hillary, Elrick, Kevin, Lu, Pouria, Mashouri, Aarthi, Mohan, Delvin, So, Conor, Klamann, Hannah G B H, Le, Andrea, Herscovich, Christian R, Marshall, Andrew, Statia, Care Rare, Canada Consortium, Bartha M, Knoppers, Michael, Brudno, Kym M, Boycott
Publikováno v:
Human mutation. 43(6)
Despite recent progress in the understanding of the genetic etiologies of rare diseases (RDs), a significant number remain intractable to diagnostic and discovery efforts. Broad data collection and sharing of information among RD researchers is there
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2509daedec9a1cd7a4cbef0069405502
https://pubmed.ncbi.nlm.nih.gov/35181971
https://pubmed.ncbi.nlm.nih.gov/35181971
Autor:
Pouria Mashouri, Krish Ohri, Andrés Nascimento Osorio, Ronald D. Cohn, Peiqui Wang, Steven A. Moore, Arun K. Ramani, Katherine D. Mathews, Hernan Gonorazky, James J. Dowling, Michael Brudno, Dwi U. Kemaladewi, Mark A. Tarnopolsky, Senthuri Viththiyapaskaran, David Villanova, Sergey Naumenko, Dennis Kao, Viswateja Nelakuditi
Publikováno v:
American Journal of Human Genetics
Gene-panel and whole-exome analyses are now standard methodologies for mutation detection in Mendelian disease. However, the diagnostic yield achieved is at best 50%, leaving the genetic basis for disease unsolved in many individuals. New approaches
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fdba481592f87c657f80ddf76ab61cd
https://doi.org/10.1016/j.ajhg.2019.01.012
https://doi.org/10.1016/j.ajhg.2019.01.012
Autor:
Vathany Kulasingam, Victor H Ferreira, Michael Brudno, Atul Humar, Bernard Lam, Myron I. Cybulsky, Trevor J. Pugh, Krista M. Pace, Natalia Pinzon, Matthew Ierullo, Ilinca Lungu, Brad Wouters, Sonika T. Humar, Paul M. Krzyzanowski, Tamara Dus, Michael Garrels, Amit M. Oza, Beata Majchrzak-Kita, Andrzej Chruscinski, Ilona Bahinskaya, Pouria Mashouri, Deepali Kumar, Tony Mazzulli, Terrance Ku, Dorin Manase, Jianhua Zhang, Lawrence E. Heisler
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0247258 (2021)
PLoS ONE
PLoS ONE
Health care workers (HCWs) are at higher risk for SARS-CoV-2 infection and may play a role in transmitting the infection to vulnerable patients and members of the community. This is particularly worrisome in the context of asymptomatic infection. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a8e0be1e1032d6d8094c0df266ccdf6
https://doaj.org/article/296e0a64cbd94bcf97642f459073385f
https://doaj.org/article/296e0a64cbd94bcf97642f459073385f
Autor:
Pouria Mashouri, Jason Fischer, Anna Goldenberg, Devin Singh, Michael Brudno, Sujay Nagaraj, Erik Drysdale
Publikováno v:
SSRN Electronic Journal.
Background: Increased patient volumes, wait-times, and long lengths of stay in emergency departments (EDs) are common healthcare challenges associated with poor patient outcomes. We propose a practical machine learning (ML) approach to autonomously o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05e99ff79db1963a3cefb2df16d8984f
https://doi.org/10.2139/ssrn.3857668
https://doi.org/10.2139/ssrn.3857668
Autor:
Brad Wouters, Michael Garrels, Myron I. Cybulsky, Victor H Ferreira, Krista M. Pace, Pouria Mashouri, Matthew Ierullo, Michael Brudno, Deepali Kumar, Andrzej Chruscinski, Atul Humar, Bernard Lam, Beata Majchrzak-Kita, Ilinca Lungu, Tony Mazzulli, Tamara Dus, Amit M. Oza, Trevor J. Pugh, Natalia Pinzon, Ilona Bahinskaya, Lawrence E. Heisler, Dorin Manase, Vathany Kulasingam, Sonika T. Humar, Paul M. Krzyzanowski, Terrance J.Y. Ku, Jianhua Zhang
We screened three separate cohorts of healthcare workers for SARS-CoV-2 via nasopharyngeal swab PCR. A seroprevalence analysis using multiple assays was performed in a subgroup. The asymptomatic health care worker cohorts had a combined swap positivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a834d260730124a4d6bd0db6e5177c7b
Autor:
Andrei L. Turinsky, Pouria Mashouri, Michael Brudno, Sanaa Choufani, Da Liu, Daniel Min, Rosanna Weksberg, Kevin N. Lu
Publikováno v:
Human mutationREFERENCES. 41(10)
Epigenetic processes play a key role in regulating gene expression. Genetic variants that disrupt chromatin-modifying proteins are associated with a broad range of diseases, some of which have specific epigenetic patterns, such as aberrant DNA methyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f03348de3d6b21e2afaf76d5a04aeb5d
https://pubmed.ncbi.nlm.nih.gov/32623772
https://pubmed.ncbi.nlm.nih.gov/32623772
Autor:
Devin, Singh, Sujay, Nagaraj, Pouria, Mashouri, Erik, Drysdale, Jason, Fischer, Anna, Goldenberg, Michael, Brudno
Publikováno v:
JAMA Network Open. 5:e222599
Increased wait times and long lengths of stay in emergency departments (EDs) are associated with poor patient outcomes. Systems to improve ED efficiency would be useful. Specifically, minimizing the time to diagnosis by developing novel workflows tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c3f8c8c4d7a42681287262452585b34
https://doi.org/10.1001/jamanetworkopen.2022.2599
https://doi.org/10.1001/jamanetworkopen.2022.2599