Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Pounami Samadder"'
Autor:
Victoria Marini, Fedor Nikulenkov, Pounami Samadder, Sissel Juul, Birgitta R. Knudsen, Lumir Krejci
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background DNA-protein cross-links (DPCs) are one of the most deleterious DNA lesions, originating from various sources, including enzymatic activity. For instance, topoisomerases, which play a fundamental role in DNA metabolic processes suc
Externí odkaz:
https://doaj.org/article/f27960dd49134ebbb90288484d64163e
Autor:
Karel Souček, Kamil Paruch, Lumír Krejčí, Aleš Hampl, Josef Jaroš, Milan Ešner, Radek Fedr, Peter Kollár, Petra Ovesná, Miroslava Bittová, Lucia Binó, Hana Kolářová, Kateřina Vašíčková, Petr Vaňhara, Nicol Straková, Stanislav Drápela, Fedor Nikulenkov, Prashant Khirsariya, Ondřej Hylse, Tereza Suchánková, Pounami Samadder
Detail description of synthesis and supporting data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::621a022e094e2d4ba0700755c1671825
https://doi.org/10.1158/1535-7163.22508934
https://doi.org/10.1158/1535-7163.22508934
Autor:
Karel Souček, Kamil Paruch, Lumír Krejčí, Aleš Hampl, Josef Jaroš, Milan Ešner, Radek Fedr, Peter Kollár, Petra Ovesná, Miroslava Bittová, Lucia Binó, Hana Kolářová, Kateřina Vašíčková, Petr Vaňhara, Nicol Straková, Stanislav Drápela, Fedor Nikulenkov, Prashant Khirsariya, Ondřej Hylse, Tereza Suchánková, Pounami Samadder
Figure S1. In vitro profiling of SCH900776 and its selected analogs. Figure S2. Analogs of MU380 with the N-trifluoromethylpyrazol pharmacophore. Figure S3. Dot plots of flow cytometric analysis using γH2AX and Annexin V staining related to Figure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c6e17c5a7b71ad8e67d5f9f5705156b
https://doi.org/10.1158/1535-7163.22508946
https://doi.org/10.1158/1535-7163.22508946
Autor:
Karel Souček, Kamil Paruch, Lumír Krejčí, Aleš Hampl, Josef Jaroš, Milan Ešner, Radek Fedr, Peter Kollár, Petra Ovesná, Miroslava Bittová, Lucia Binó, Hana Kolářová, Kateřina Vašíčková, Petr Vaňhara, Nicol Straková, Stanislav Drápela, Fedor Nikulenkov, Prashant Khirsariya, Ondřej Hylse, Tereza Suchánková, Pounami Samadder
Detail description of Material and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca2af450a9710cf2c3505b94fce584e3
https://doi.org/10.1158/1535-7163.22508937
https://doi.org/10.1158/1535-7163.22508937
Autor:
Karel Souček, Kamil Paruch, Lumír Krejčí, Aleš Hampl, Josef Jaroš, Milan Ešner, Radek Fedr, Peter Kollár, Petra Ovesná, Miroslava Bittová, Lucia Binó, Hana Kolářová, Kateřina Vašíčková, Petr Vaňhara, Nicol Straková, Stanislav Drápela, Fedor Nikulenkov, Prashant Khirsariya, Ondřej Hylse, Tereza Suchánková, Pounami Samadder
Supplementary Legends for Supplemetary Figure S1 - S11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b70d35fe48e8779e16a93830d0eae56
https://doi.org/10.1158/1535-7163.22508940
https://doi.org/10.1158/1535-7163.22508940
Publikováno v:
Pharmacologytherapeutics. 161
Cancer is a disease attributed to the accumulation of DNA damages due to incapacitation of DNA repair pathways resulting in genomic instability and a mutator phenotype. Among the DNA lesions, double stranded breaks (DSBs) are the most toxic forms of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc32ff5abe226935f3c722db277cf396
https://pubmed.ncbi.nlm.nih.gov/26899499
https://pubmed.ncbi.nlm.nih.gov/26899499