Zobrazeno 1 - 10
of 331
pro vyhledávání: '"Potter, BVL"'
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 12, Pp 1881-1904 (2018)
Marcel Nel,1 Anna M Joubert,1 Wolfgang Dohle,2 Barry VL Potter,2 Anne E Theron1 1Department of Physiology, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa; 2Medicinal Chemistry & Drug Discovery, Department of Pharmacology,
Externí odkaz:
https://doaj.org/article/a95953f43bf04b979573d463e71d4ee6
Autor:
Hosang, L, Löhndorf, A, Dohle, W, Rosche, A, Marry, S, Diercks, B-P, Müller-Kirschbaum, LC, Flügel, LT, Potter, BVL, Odoardi, F, Guse, AH, Flügel, A
Ca2+ signaling is one of the essential signaling systems for T lymphocyte activation, the latter being an essential step in the pathogenesis of autoimmune diseases such as multiple sclerosis (MS). Store-operated Ca2+ entry (SOCE) ensures long lasting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eadf1508427103e83fb5eba23c448ad
https://doi.org/10.1016/j.bbamcr.2023.119485
https://doi.org/10.1016/j.bbamcr.2023.119485
The antifungal drug itraconazole has been repurposed to anti-angiogenic agent, but the mechanisms of action have been elusive. Here we report that itraconazole disrupts focal adhesion dynamics and cytoskeletal remodeling, which requires 5-diphosphoin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::da6523c3b60e16be773251c10e7cb60d
https://doi.org/10.1016/j.biopha.2023.114449
https://doi.org/10.1016/j.biopha.2023.114449
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Cyclic adenosine 5′-diphosphate ribose (cADPR) is an emerging Ca2+-mobilising second messenger. cADPR analogues have been generated as chemical biology tools via both chemo-enzymatic and total synthetic routes. Both routes rely on the cyclisation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::674d46e9fcbe00316e125416ce61a5a0
http://link.springer.com/article/10.1038/s41598-018-33484-x
http://link.springer.com/article/10.1038/s41598-018-33484-x
Diphosphoinositol phosphates (PP-InsPs) are inositol phosphates (InsPs) that contain PP (diphosphate) groups. Converting a phosphate group in an InsP into a diphosphate has been reported to enhance affinity for some binding proteins. We synthesised 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0d9438fb2aa9ddbd7a987224e3485b06
https://ora.ox.ac.uk/objects/uuid:434ca48f-72f0-4d7b-a407-8d68ec74e976
https://ora.ox.ac.uk/objects/uuid:434ca48f-72f0-4d7b-a407-8d68ec74e976
Autor:
Raimondi, C, Calleja, V, Ferro, R, Fantin, A, Riley, AM, Potter, BVL, Brennan, CH, Maffucci, T, Larijani, B, Falasca, M
Publikováno v:
Scientific Reports. 6
Strong evidence suggests that phospholipase Cγ1 (PLCγ1) is a suitable target to counteract tumourigenesis and metastasis dissemination. We recently identified a novel signalling pathway required for PLCγ1 activation which involves formation of a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::d9a951e1d33514e1ea82a2cc1dfb7363
http://ora.ox.ac.uk/objects/uuid:
http://ora.ox.ac.uk/objects/uuid:
Autor:
L, MacCarthy-Morrogh, P A, Townsend, A, Purohit, Hejaz HAM, Potter BVL, M J, Reed, G, Packham
Publikováno v:
Cancer research. 60(19)
There is considerable interest in the potential use of estrogen derivatives for the treatment and prevention of breast cancer. We demonstrated previously that the sulfamoylated estrone derivative 2-methoxyestrone-3-O-sulfamate (2-MeOEMATE) induced G2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4e6e13a152b9dc2cc5eb4e3a23b42d18
https://pubmed.ncbi.nlm.nih.gov/11034086
https://pubmed.ncbi.nlm.nih.gov/11034086
Autor:
Potter Bvl.
Publikováno v:
ACS Symposium Series ISBN: 9780841220867
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb8c699fcc393c8370b6732ab10cd6c0
https://doi.org/10.1021/bk-1991-0463.ch014
https://doi.org/10.1021/bk-1991-0463.ch014
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Akademický článek
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