Zobrazeno 1 - 10
of 928
pro vyhledávání: '"Potter, BVL"'
Autor:
Liu X; Tianjin Key Laboratory of Metabolic Diseases, Department of Physiology and Pathophysiology, The Province and Ministry Co-Sponsored Collaborative Innovation Center for Medical Epigenetics, Tianjin Medical University, 22 Qixiangtai Road, Tianjin 300070, China., Zhang Z; Tianjin Key Laboratory of Metabolic Diseases, Department of Physiology and Pathophysiology, The Province and Ministry Co-Sponsored Collaborative Innovation Center for Medical Epigenetics, Tianjin Medical University, 22 Qixiangtai Road, Tianjin 300070, China., Aguirre T; Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin 13125, Germany., Shipton ML; Medicinal Chemistry & Drug Discovery, Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, UK., Fu L; Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, Tianjin 300211, China., Du J; Tianjin Key Laboratory of Metabolic Diseases, Department of Physiology and Pathophysiology, The Province and Ministry Co-Sponsored Collaborative Innovation Center for Medical Epigenetics, Tianjin Medical University, 22 Qixiangtai Road, Tianjin 300070, China., Furkert D; Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin 13125, Germany., Qi J; Institute for Developmental and Regenerative Cardiovascular Medicine, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200092, China., Chin AC; Weill Cornell/Rockefeller/Sloan Kettering Tri-Institutional MD-PhD Program, New York, NY 10065, USA., Riley AM; Medicinal Chemistry & Drug Discovery, Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, UK., Liu T; Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, Tianjin 300211, China., Zhang X; Tianjin Key Laboratory of Metabolic Diseases, Department of Physiology and Pathophysiology, The Province and Ministry Co-Sponsored Collaborative Innovation Center for Medical Epigenetics, Tianjin Medical University, 22 Qixiangtai Road, Tianjin 300070, China., Potter BVL; Medicinal Chemistry & Drug Discovery, Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, UK., Fiedler D; Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin 13125, Germany., Zhu Y; Tianjin Key Laboratory of Metabolic Diseases, Department of Physiology and Pathophysiology, The Province and Ministry Co-Sponsored Collaborative Innovation Center for Medical Epigenetics, Tianjin Medical University, 22 Qixiangtai Road, Tianjin 300070, China. Electronic address: zhuyi@tmu.edu.cn., Fu C; Tianjin Key Laboratory of Metabolic Diseases, Department of Physiology and Pathophysiology, The Province and Ministry Co-Sponsored Collaborative Innovation Center for Medical Epigenetics, Tianjin Medical University, 22 Qixiangtai Road, Tianjin 300070, China; Institute for Developmental and Regenerative Cardiovascular Medicine, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200092, China. Electronic address: fuchenglai@xinhuamed.com.cn.
Publikováno v:
Metabolism: clinical and experimental [Metabolism] 2024 Dec 04, pp. 156098. Date of Electronic Publication: 2024 Dec 04.
Autor:
Fu L; Tianjin Key Laboratory of Metabolic Diseases, Department of Physiology and Pathophysiology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Tianjin Medical University, 22 Qixiangtai Road, Heping District, Tianjin 300070, China., Du J; Tianjin Key Laboratory of Metabolic Diseases, Department of Physiology and Pathophysiology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Tianjin Medical University, 22 Qixiangtai Road, Heping District, Tianjin 300070, China., Furkert D; Leibniz-Forschungsinstitut für Molekulare Pharmakologie, Berlin, Germany., Shipton ML; Medicinal Chemistry and Drug Discovery, Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, UK., Liu X; Tianjin Key Laboratory of Metabolic Diseases, Department of Physiology and Pathophysiology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Tianjin Medical University, 22 Qixiangtai Road, Heping District, Tianjin 300070, China., Aguirre T; Leibniz-Forschungsinstitut für Molekulare Pharmakologie, Berlin, Germany., Chin AC; Weill Cornell/Rockefeller/Sloan Kettering Tri-Institutional MD-PhD Program, New York, NY, USA., Riley AM; Medicinal Chemistry and Drug Discovery, Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, UK., Potter BVL; Medicinal Chemistry and Drug Discovery, Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, UK., Fiedler D; Leibniz-Forschungsinstitut für Molekulare Pharmakologie, Berlin, Germany., Zhang X; Tianjin Key Laboratory of Metabolic Diseases, Department of Physiology and Pathophysiology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Tianjin Medical University, 22 Qixiangtai Road, Heping District, Tianjin 300070, China., Zhu Y; Tianjin Key Laboratory of Metabolic Diseases, Department of Physiology and Pathophysiology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Tianjin Medical University, 22 Qixiangtai Road, Heping District, Tianjin 300070, China., Fu C; Tianjin Key Laboratory of Metabolic Diseases, Department of Physiology and Pathophysiology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Tianjin Medical University, 22 Qixiangtai Road, Heping District, Tianjin 300070, China.; Institute for Developmental and Regenerative Cardiovascular Medicine, Xinhua Hospital affiliated to Shanghai Jiao Tong University School of Medicine, 1665 Kongjiang Road, Yangpu District, Shanghai 200092, China.
Publikováno v:
Cardiovascular research [Cardiovasc Res] 2024 Jul 02; Vol. 120 (8), pp. 954-970.
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 12, Pp 1881-1904 (2018)
Marcel Nel,1 Anna M Joubert,1 Wolfgang Dohle,2 Barry VL Potter,2 Anne E Theron1 1Department of Physiology, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa; 2Medicinal Chemistry & Drug Discovery, Department of Pharmacology,
Externí odkaz:
https://doaj.org/article/a95953f43bf04b979573d463e71d4ee6
Autor:
Hosang, L, Löhndorf, A, Dohle, W, Rosche, A, Marry, S, Diercks, B-P, Müller-Kirschbaum, LC, Flügel, LT, Potter, BVL, Odoardi, F, Guse, AH, Flügel, A
Ca2+ signaling is one of the essential signaling systems for T lymphocyte activation, the latter being an essential step in the pathogenesis of autoimmune diseases such as multiple sclerosis (MS). Store-operated Ca2+ entry (SOCE) ensures long lasting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eadf1508427103e83fb5eba23c448ad
https://doi.org/10.1016/j.bbamcr.2023.119485
https://doi.org/10.1016/j.bbamcr.2023.119485
The antifungal drug itraconazole has been repurposed to anti-angiogenic agent, but the mechanisms of action have been elusive. Here we report that itraconazole disrupts focal adhesion dynamics and cytoskeletal remodeling, which requires 5-diphosphoin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::da6523c3b60e16be773251c10e7cb60d
https://doi.org/10.1016/j.biopha.2023.114449
https://doi.org/10.1016/j.biopha.2023.114449
Autor:
Zaraei SO; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah 27272, United Arab Emirates., Dohle W; Medicinal Chemistry and Drug Discovery, Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, United Kingdom., Anbar HS; Department of Pharmaceutical Sciences, Dubai Pharmacy College for Girls, Dubai 19099, United Arab Emirates., El-Gamal R; Department of Medical Biochemistry, Faculty of Medicine, Mansoura University, Mansoura 35516, Egypt., Leblond B; Medicinal Chemistry, Department of Life Sciences, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom., Foster PA; Institute of Metabolism and Systems Research, 2(nd) Floor IBR Tower, University of Birmingham, Birmingham B15 2TT, United Kingdom; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham B15 2TH, United Kingdom., Al-Tel TH; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah 27272, United Arab Emirates; Department of Medicinal Chemistry, College of Pharmacy, University of Sharjah, Sharjah 27272, United Arab Emirates., Potter BVL; Medicinal Chemistry and Drug Discovery, Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, United Kingdom; Medicinal Chemistry, Department of Life Sciences, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom. Electronic address: barry.potter@pharm.ox.ac.uk., El-Gamal MI; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah 27272, United Arab Emirates; Department of Medicinal Chemistry, College of Pharmacy, University of Sharjah, Sharjah 27272, United Arab Emirates; Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt. Electronic address: drmelgamal2002@gmail.com.
Publikováno v:
Bioorganic & medicinal chemistry [Bioorg Med Chem] 2024 Mar 01; Vol. 101, pp. 117645. Date of Electronic Publication: 2024 Feb 16.
Autor:
Márquez-Moñino MÁ; Department of Crystallography and Structural Biology, Institute of Physical-Chemistry Blas Cabrera, CSIC, Serrano 119, 28006, Madrid, Spain., Ortega-García R; Department of Crystallography and Structural Biology, Institute of Physical-Chemistry Blas Cabrera, CSIC, Serrano 119, 28006, Madrid, Spain., Whitfield H; School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, UK., Riley AM; Drug Discovery and Medicinal Chemistry, Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK., Infantes L; Department of Crystallography and Structural Biology, Institute of Physical-Chemistry Blas Cabrera, CSIC, Serrano 119, 28006, Madrid, Spain., Garrett SW; Wolfson Laboratory of Medicinal Chemistry, Department of Life Sciences, University of Bath, Claverton Down, Bath, BA2 7AY, UK., Shipton ML; Drug Discovery and Medicinal Chemistry, Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK., Brearley CA; School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, UK., Potter BVL; Drug Discovery and Medicinal Chemistry, Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK. barry.potter@pharm.ox.ac.uk.; Wolfson Laboratory of Medicinal Chemistry, Department of Life Sciences, University of Bath, Claverton Down, Bath, BA2 7AY, UK. barry.potter@pharm.ox.ac.uk., González B; Department of Crystallography and Structural Biology, Institute of Physical-Chemistry Blas Cabrera, CSIC, Serrano 119, 28006, Madrid, Spain. xbeatriz@iqf.csic.es.
Publikováno v:
Nature communications [Nat Commun] 2024 Feb 19; Vol. 15 (1), pp. 1502. Date of Electronic Publication: 2024 Feb 19.
Autor:
Whitfield HL; School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich NR4 7TJ, U.K., Rodriguez RF; School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich NR4 7TJ, U.K.; School of Chemistry, University of East Anglia, Norwich Research Park, Norwich NR4 7TJ, U.K., Shipton ML; Medicinal Chemistry & Drug Discovery, Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, U.K., Li AWH; School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich NR4 7TJ, U.K.; School of Chemistry, University of East Anglia, Norwich Research Park, Norwich NR4 7TJ, U.K., Riley AM; Medicinal Chemistry & Drug Discovery, Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, U.K., Potter BVL; Medicinal Chemistry & Drug Discovery, Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, U.K., Hemmings AM; School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich NR4 7TJ, U.K.; School of Chemistry, University of East Anglia, Norwich Research Park, Norwich NR4 7TJ, U.K.; College of Food Science and Technology, Shanghai Ocean University, Shanghai 201306, China., Brearley CA; School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich NR4 7TJ, U.K.
Publikováno v:
Biochemistry [Biochemistry] 2024 Jan 02; Vol. 63 (1), pp. 42-52. Date of Electronic Publication: 2023 Dec 26.
Autor:
Anbar HS; Department of Clinical Pharmacy and Pharmacotherapeutics, Dubai Pharmacy College for Girls, Dubai, 19099, United Arab Emirates. Electronic address: dr.hanan@dpc.edu., Vahora NY; Dubai Pharmacy College for Girls, Dubai, 19099, United Arab Emirates., Shah HL; Dubai Pharmacy College for Girls, Dubai, 19099, United Arab Emirates., Azam MM; Dubai Pharmacy College for Girls, Dubai, 19099, United Arab Emirates., Islam T; Dubai Pharmacy College for Girls, Dubai, 19099, United Arab Emirates., Hersi F; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates., Omar HA; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates; Department of Pharmacy Practice and Pharmacotherapeutics, College of Pharmacy, University of Sharjah, Sharjah, 27272, United Arab Emirates; Faculty of Pharmacy, Beni-Suef University, Beni-Suef, 62514, Egypt., Dohle W; Medicinal Chemistry & Drug Discovery, Department of Pharmacology, University of Oxford, Oxford, OX1 3QT, United Kingdom., Potter BVL; Medicinal Chemistry & Drug Discovery, Department of Pharmacology, University of Oxford, Oxford, OX1 3QT, United Kingdom., El-Gamal MI; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates; Department of Medicinal Chemistry, College of Pharmacy, University of Sharjah, Sharjah, 27272, United Arab Emirates; Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt.
Publikováno v:
European journal of pharmacology [Eur J Pharmacol] 2023 Dec 05; Vol. 960, pp. 176119. Date of Electronic Publication: 2023 Oct 16.
Autor:
Hostachy S; Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Rössle-Straße 10, 13125, Berlin, Germany., Wang H; Inositol Signaling Group, National Institutes of Health, Research Triangle Park, North Carolina, 27709, USA., Zong G; Inositol Signaling Group, National Institutes of Health, Research Triangle Park, North Carolina, 27709, USA., Franke K; Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Rössle-Straße 10, 13125, Berlin, Germany., Riley AM; Medicinal Chemistry & Drug Discovery Department of Pharmacology, University of Oxford, Oxford, OX1 3QT, UK., Schmieder P; Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Rössle-Straße 10, 13125, Berlin, Germany., Potter BVL; Medicinal Chemistry & Drug Discovery Department of Pharmacology, University of Oxford, Oxford, OX1 3QT, UK., Shears SB; Inositol Signaling Group, National Institutes of Health, Research Triangle Park, North Carolina, 27709, USA., Fiedler D; Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Rössle-Straße 10, 13125, Berlin, Germany.; Institut für Chemie, Humboldt-Universität zu Berlin, Brook-Taylor-Str. 2, 12489, Berlin, Germany.
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2023 Dec 01; Vol. 29 (67), pp. e202302426. Date of Electronic Publication: 2023 Oct 19.