Výsledky vyhledávání - "Pothoulakis C"

Akademický článek

Review article: anti-inflammatory mechanisms of action of Saccharomyces boulardii.

Autor: POTHOULAKIS, C.¹ (AUTHOR)

Publikováno v: Alimentary Pharmacology & Therapeutics. Oct2009, Vol. 30 Issue 8, p826-833. 8p. 1 Diagram.

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Neurotensin Promotes the Development of Colitis and Intestinal Angiogenesis via Hif-1 alpha-miR-210 Signaling

Autor: Bakirtzi, K, Law, IKM, Xue, X, Iliopoulos, D, Shah, YM, Pothoulakis, C

Publikováno v: Bakirtzi, K; Law, IKM; Xue, X; Iliopoulos, D; Shah, YM; & Pothoulakis, C. (2016). Neurotensin Promotes the Development of Colitis and Intestinal Angiogenesis via Hif-1 alpha-miR-210 Signaling. JOURNAL OF IMMUNOLOGY, 196(10), 4311-4321. doi: 10.4049/jimmunol.1501443. UCLA: Retrieved from: http://www.escholarship.org/uc/item/91b831w9

Neurotensin (NT) via its receptor 1 (NTR1) modulates the development of colitis, decreases HIF-1α/PHD2 interaction, stabilizes and increases HIF-1α transcriptional activity, and promotes intestinal angiogenesis. HIF-1α induces miR-210 expression,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::c11e225ef55090270535dfa8b7584b06
http://www.escholarship.org/uc/item/91b831w9

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Neurotensin-induced miR-133 alpha expression regulates neurotensin receptor 1 recycling through its downstream target aftiphilin

Autor: Law, IKM, Jensen, D, Bunnett, NW, Pothoulakis, C

Publikováno v: Law, IKM; Jensen, D; Bunnett, NW; & Pothoulakis, C. (2016). Neurotensin-induced miR-133 alpha expression regulates neurotensin receptor 1 recycling through its downstream target aftiphilin. SCIENTIFIC REPORTS, 6. doi: 10.1038/srep22195. UCLA: Retrieved from: http://www.escholarship.org/uc/item/8wt7s68n

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http://www.escholarship.org/uc/item/8wt7s68n

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Identification of a novel interaction between corticotropin releasing hormone (Crh) and macroautophagy

Autor: Giannogonas, P. Apostolou, A. Manousopoulou, A. Theocharis, S. MacAri, S.A. Psarras, S. Garbis, S.D. Pothoulakis, C. Karalis, K.P.

In inflammatory bowel disease (IBD), compromised restitution of the epithelial barrier contributes to disease severity. Owing to the complexity in the pathogenesis of IBD, a variety of factors have been implicated in its progress. In this study, we r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::d203fab8f83ada2062986bb69f38da47
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3056812

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Novel approaches to treating Clostridium difficile-associated colitis

Autor: Padua, D, Pothoulakis, C

Publikováno v: Expert review of gastroenterology & hepatology, vol 10, iss 2
Padua, D; & Pothoulakis, C. (2015). Novel approaches to treating Clostridium difficile-associated colitis. Expert Review of Gastroenterology and Hepatology, 1-12. doi: 10.1586/17474124.2016.1109444. UCLA: Retrieved from: http://www.escholarship.org/uc/item/1w43q6dd

© 2015 Taylor & Francis Clostridium difficile is being recognized as a growing threat to many health-care systems. Epidemiology data shows that infection rates are soaring and the disease burden is increasing. Despite the efficacy of standard treatm

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https://escholarship.org/uc/item/1w43q6dd

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Akademický článek

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Reciprocal Regulation of Substance P and IL-12/IL-23 and the Associated Cytokines, IFNγ/IL-17: A Perspective on the Relevance of This Interaction to Multiple Sclerosis

Autor: Vilisaar, J, Kawabe, K, Braitch, M, Aram, J, Furtun, Y, Fahey, AJ, Chopra, M, Tanasescu, R, Tighe, PJ, Gran, B, Pothoulakis, C, Constantinescu, CS

Publikováno v: Vilisaar, J; Kawabe, K; Braitch, M; Aram, J; Furtun, Y; Fahey, AJ; et al.(2015). Reciprocal Regulation of Substance P and IL-12/IL-23 and the Associated Cytokines, IFNγ/IL-17: A Perspective on the Relevance of This Interaction to Multiple Sclerosis. Journal of Neuroimmune Pharmacology. doi: 10.1007/s11481-015-9589-x. UCLA: Retrieved from: http://www.escholarship.org/uc/item/4qf0r4r7

© 2015 The Author(s) The neuropeptide substance P (SP) exhibits cytokine-like properties and exerts different effects in autoimmune inflammation. Various immune cells express SP and its neurokinin-1 receptor (NK1R) isoforms. A role for SP has been d

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http://www.escholarship.org/uc/item/4qf0r4r7

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MicroRNA214 Is Associated With Progression of Ulcerative Colitis, and Inhibition Reduces Development of Colitis and Colitis-Associated Cancer in Mice

Autor: Polytarchou, C, Hommes, DW, Palumbo, T, Hatziapostolou, M, Koutsioumpa, M, Koukos, G, van der Meulen-de Jong, AE, Oikonomopoulos, A, van Deen, WK, Vorvis, C, Serebrennikova, OB, Birli, E, Choi, J, Chang, L, Anton, PA, Tsichlis, PN, Pothoulakis, C, Verspaget, HW, Iliopoulos, D

Publikováno v: Polytarchou, C; Hommes, DW; Hommes, DW; Palumbo, T; Hatziapostolou, M; Koutsioumpa, M; et al.(2015). MicroRNA214 Is Associated With Progression of Ulcerative Colitis, and Inhibition Reduces Development of Colitis and Colitis-Associated Cancer in Mice. Gastroenterology. doi: 10.1053/j.gastro.2015.05.057. UCLA: Retrieved from: http://www.escholarship.org/uc/item/6c5661g0

© 2015 AGA Institute. Background & Aims: Persistent activation of the inflammatory response contributes to the development of inflammatory bowel diseases, which increase the risk of colorectal cancer. We aimed to identify microRNAs that regulate inf

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http://www.escholarship.org/uc/item/6c5661g0

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MicroRNA-133α regulates neurotensin-associated colonic inflammation in colonic epithelial cells and experimental colitis

Autor: Law, IKM, Pothoulakis, C

Publikováno v: Law, IKM; & Pothoulakis, C. (2015). MicroRNA-133α regulates neurotensin-associated colonic inflammation in colonic epithelial cells and experimental colitis.. RNA & disease (Houston, Tex.), 2(1). doi: 10.14800/rd.472. UCLA: Retrieved from: http://www.escholarship.org/uc/item/4mq107qs

Ulcerative colitis (UC) and Crohn's Disease (CD) are the two most common forms of Inflammatory Bowel Diseases (IBD) marked by chronic and persistent inflammation. Neurotensin (NT), together with its receptor, NT receptor 1 (NTR1), are important media

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