Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Potchanapond Graidist"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Binding affinity is an important factor in drug design to improve drug-target selectivity and specificity. In this study, in silico techniques based on molecular docking followed by molecular dynamics (MD) simulations were utilized to identi
Externí odkaz:
https://doaj.org/article/0cf4a57ed9e546a495981047a784be80
Autor:
Jirakrit Saetang, Aman Tedasen, Surasak Sangkhathat, Natnaree Sangkaew, Sirinapa Dokduang, Napat Prompat, Siriporn Taraporn, Potchanapond Graidist
Publikováno v:
Pharmaceutical Biology, Vol 60, Iss 1, Pp 96-107 (2022)
Context Many natural extracts have been shown to minimize the toxicity of doxorubicin (Dox). Low piperine Piper nigrum L. (Piperaceae) extract (PFPE) is a natural extract containing many types of antioxidants that may reduce Dox toxicities. Objective
Externí odkaz:
https://doaj.org/article/e229faa548ed45d689f9207f314eb135
Autor:
Thidarath Rattanaburee, Chompunud Chompunud Na Ayudhya, Tienthong Thongpanchang, Varomyalin Tipmanee, Potchanapond Graidist
Publikováno v:
Molecules, Vol 28, Iss 21, p 7342 (2023)
This research aimed to determine the target protein and molecular mechanism of trans-(±)-kusunokinin ((±)-KU) derivatives (trans-(±)-ARC and trans-(±)-TTPG-B). Molecular docking was used to predict potential synthesized (±)-KU targets among 22 p
Externí odkaz:
https://doaj.org/article/676cf14276ec455e80768fbe7ba462b3
Autor:
Saowanee Maungchanburi, Thidarath Rattanaburee, Yaowapa Sukpondma, Aman Tedasen, Varomyalin Tipmanee, Potchanapond Graidist
Publikováno v:
Journal of Pharmacy & Pharmacognosy Research, Vol 10, Iss 1, Pp 39-51 (2022)
Context: Piper cubeba L. (family Piperaceae) is used traditionally for the treatment of many diseases, including cancer. Aims: To determine the anticancer activity of P. cubeba crude extracts on cancer cells and identify chemical constituents of t
Externí odkaz:
https://doaj.org/article/a3e467617d6b4518aca217982349ca77
Publikováno v:
Foods, Vol 12, Iss 10, p 2053 (2023)
A low piperine fractional Piper nigrum extract (PFPE) was prepared by mixing cold-pressed coconut oil and honey in distilled water, namely, PFPE-CH. In this study, PFPE-CH was orally administered as a dietary supplement to decrease the risk of tumor
Externí odkaz:
https://doaj.org/article/f4919f9f06e2402187dbfa664552dea4
Autor:
Tanotnon Tanawattanasuntorn, Tienthong Thongpanchang, Thanyada Rungrotmongkol, Chonnikan Hanpaibool, Potchanapond Graidist, Varomyalin Tipmanee
Publikováno v:
ACS Omega, Vol 6, Iss 1, Pp 606-614 (2020)
Externí odkaz:
https://doaj.org/article/50bf860425674b0e90e9595ee35d6675
Autor:
Tanotnon Tanawattanasuntorn, Thidarath Rattanaburee, Tienthong Thongpanchang, Potchanapond Graidist
Publikováno v:
Antioxidants, Vol 11, Iss 12, p 2347 (2022)
Synthetic trans-(±)-kusunokinin ((±)KU), a potential anticancer substance, was revealed to have an inhibitory effect on breast cancer. According to the computational modeling prediction, AKR1B1, an oxidative stress and cancer migration protein, cou
Externí odkaz:
https://doaj.org/article/8d14bdce8fc74a1da60d3a5cde5ba3b8
Autor:
Thidarath Rattanaburee, Patpanat Sermmai, Kornthip Tangthana-umrung, Tienthong Thongpanchang, Potchanapond Graidist
Publikováno v:
Molecules, Vol 27, Iss 23, p 8291 (2022)
This study aimed to investigate the cytotoxicity and anticancer activity of (±)-kusunokinin derivatives ((±)-TTPG-A and (±)-TTPG-B). The cytotoxicity effect was performed on human cancer cells, including breast cancer, cholangiocarcinoma, colon an
Externí odkaz:
https://doaj.org/article/eb957a3555e64bf6bb593c86c586d473
Publikováno v:
Molecules, Vol 27, Iss 13, p 4194 (2022)
Breast cancer cell proliferation and migration are inhibited by naturally extracted trans-(−)-kusunokinin. However, three additional enantiomers of kusunokinin have yet to be investigated: trans-(+)-kusunokinin, cis-(−)-isomer and cis-(+)-isomer.
Externí odkaz:
https://doaj.org/article/7b2f40e56fb4479a98dbe9d92ee1fb39
Autor:
Siriphorn Chimplee, Sittiruk Roytrakul, Suchada Sukrong, Theera Srisawat, Potchanapond Graidist, Kanyanatt Kanokwiroon
Publikováno v:
Molecules, Vol 27, Iss 2, p 407 (2022)
Triple negative breast cancer (TNBC) is a breast cancer subtype characterized by the absence of estrogen receptor, progesterone receptor and human epidermal growth factor receptor 2 expression. TNBC cells respond poorly to targeted chemotherapies cur
Externí odkaz:
https://doaj.org/article/6d60f43305244898a06d2c87699a914c