Zobrazeno 1 - 10
of 1 413
pro vyhledávání: '"Postsynaptic currents"'
Autor:
Hyosang Kim, Eunjoon Kim
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2024)
ARID1B, a chromatin remodeler, is strongly implicated in autism spectrum disorders (ASD). Two previous studies on Arid1b-mutant mice with the same exon 5 deletion in different genetic backgrounds revealed distinct synaptic phenotypes underlying the b
Externí odkaz:
https://doaj.org/article/00e7a9283f53467480f05e0bd70632b3
Autor:
Stuart M. Cain, Sascha R. A. Alles, Ray Gopaul, Louis-Philippe Bernier, Andrew C. Yung, Andrew Bauman, Yi Yang, Glen B. Baker, Piotr Kozlowski, Brian A. MacVicar, Terrance P. Snutch
Publikováno v:
Molecular Brain, Vol 16, Iss 1, Pp 1-14 (2023)
Abstract Familial hemiplegic migraine type-1 (FHM-1) is a form of migraine with aura caused by mutations in the P/Q-type (Cav2.1) voltage-gated calcium channel. Pregabalin, used clinically in the treatment of chronic pain and epilepsy, inhibits P/Q-t
Externí odkaz:
https://doaj.org/article/7f60fbce64114253a4fc70c967d52dd5
Autor:
Ke Cheng, Yue Wang, Yong He, Yu Tian, Junjie Li, Chong Chen, Xingzhe Xu, Zhonghao Wu, Heming Yu, Xiangyu Chen, Yili Wu, Weihong Song, Zhifang Dong, Huatai Xu, Peng Xie
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-14 (2023)
Abstract Carbonic Anhydrase 1 (CAR1) is a zinc-metalloenzyme that catalyzes the hydration of carbon dioxide, and the alteration of CAR1 has been implicated in neuropsychiatric disorders. However, the mechanism underlying the role of CAR1 in major dep
Externí odkaz:
https://doaj.org/article/40779fbd53c7457dadf7693a13944c94
Publikováno v:
Advanced Intelligent Systems, Vol 5, Iss 11, Pp n/a-n/a (2023)
The enhancement of long‐term memory properties in optical synaptic devices based on ZnO nanoparticles (NPs) is investigated. High‐temperature annealing improves crystal quality and carrier mobility, leading to efficient carrier generation and tra
Externí odkaz:
https://doaj.org/article/c2b26ce10737429c8d301611128b4424
Autor:
Marcus S. Dyer, G. Lorenzo Odierna, Rosemary M. Clark, Adele Woodhouse, Catherine A. Blizzard
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Amyotrophic Lateral Sclerosis (ALS) is an incurable disease characterized by relentlessly progressive degeneration of the corticomotor system. Cortical hyperexcitability has been identified as an early pre-symptomatic biomarker of ALS. This suggests
Externí odkaz:
https://doaj.org/article/a373b867b43d4c239e7494e29d163436
Publikováno v:
Frontiers in Ophthalmology, Vol 3 (2023)
The retina is comprised of diverse neural networks, signaling from photoreceptors to ganglion cells to encode images. The synaptic connections between these retinal neurons are crucial points for information transfer; however, the input-output relati
Externí odkaz:
https://doaj.org/article/6f28d5177ff1404cbe47cd63b953d3ca
Autor:
Brandon J. Thio, Warren M. Grill
Publikováno v:
NeuroImage, Vol 275, Iss , Pp 120179- (2023)
Dogma dictates that the EEG signal is generated by postsynaptic currents (PSCs) because there are an enormous number of synapses in the brain, and PSCs have relatively long durations. However, PSCs are not the only potential source of electric fields
Externí odkaz:
https://doaj.org/article/cce31765754542a581479856cfd3a2ef
Autor:
Min-Yi Wu, Wen-Jun Zou, Pei Yu, Yuhua Yang, Shao-Jian Li, Qiang Liu, Jiatian Xie, Si-Qi Chen, Wei-Jye Lin, Yamei Tang
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 10, Pp 2253-2259 (2022)
Radiation therapy is a standard treatment for head and neck tumors. However, patients often exhibit cognitive impairments following radiation therapy. Previous studies have revealed that hippocampal dysfunction, specifically abnormal hippocampal neur
Externí odkaz:
https://doaj.org/article/3fd46700f7a84fbda2d36eb73af59fb9
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Hypoinsulinemia is a pathological consequence of diabetes mellitus that can cause a number of complications of the central and peripheral nervous system. Dysfunction of signaling cascades of insulin receptors under insulin deficiency can contribute t
Externí odkaz:
https://doaj.org/article/30cec3fb30c04af8b10c2514016f5ecf
Autor:
Hanna Dumanska, Nikolai Veselovsky
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
The identification of processes and mechanisms underlying the early stage of hypoxic injury of the retinocollicular pathway may be beneficial for the future prevention and treatment of navigation, orientation, and visual attention impairments. Previo
Externí odkaz:
https://doaj.org/article/0afe92fd493a48e6979d23c902ee896d