Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Posterior Sex Combs"'
Publikováno v:
J Mol Biol
Polycomb Group proteins regulate gene expression by modifying chromatin. Polycomb Repressive Complex 1 (PRC1) has two activities: a ubiquitin ligase activity for histone H2A, and a chromatin compacting activity. In Drosophila, the Posterior Sex Combs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc202f32eafc419e821322b794359d47
https://doi.org/10.1016/j.jmb.2020.07.002
https://doi.org/10.1016/j.jmb.2020.07.002
Polycomb Group (PcG) proteins regulate gene expression by modifying chromatin. A key PcG complex, Polycomb Repressive Complex 1 (PRC1), has two activities: a ubiquitin ligase activity for histone H2A, and a chromatin compacting activity. InDrosophila
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e8dba4f087362e494853964bfb0dd29
https://doi.org/10.1101/2020.06.02.130492
https://doi.org/10.1101/2020.06.02.130492
Publikováno v:
Genetics. 205:551-558
Polycomb group (PcG) proteins are major chromatin-bound factors that can read and modify chromatin states to maintain gene silencing throughout development. Here we focus on a close homolog of the PcG protein Posterior sex combs to better understand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c6ffe0c340d10262de511781fadbce7
https://doi.org/10.1534/genetics.116.187849
https://doi.org/10.1534/genetics.116.187849
Autor:
Heather Collins, Nam Sung Moon
Publikováno v:
G3: Genes|Genomes|Genetics
A Polycomb group protein, Posterior sex combs (Psc), was identified in a genetic screen designed to find factors that can specifically induce morphological defects in rbf1 mutant eyes. We discovered that rbf1 mutations enhance developmental phenotype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da9bbc85bc9bd48c93b0e463f7157643
http://europepmc.org/articles/PMC3789789
http://europepmc.org/articles/PMC3789789
Publikováno v:
Epigenetics. 7:482-491
Polycomb repression controls the expression of hundreds of genes involved in development and is mediated by essentially two classes of chromatin-associated protein complexes. The Polycomb repressive complex 2 (PRC2) trimethylates histone H3 at lysine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::641777cb3813741c85e08058550c2548
https://doi.org/10.4161/epi.19741
https://doi.org/10.4161/epi.19741
Autor:
Stanley M. Lo, Nicole J. Francis
Publikováno v:
Biochemistry. 49:9438-9448
Polycomb Group (PcG) proteins are essential regulators of development that maintain gene silencing in Drosophila and mammals through alterations of chromatin structure. One key PcG protein, Posterior Sex Combs (PSC), is part of at least two complexes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c046ebdcdcf3016feb4d65b93eab0f46
https://doi.org/10.1021/bi100532a
https://doi.org/10.1021/bi100532a
Publikováno v:
The EMBO Journal
An important facet of transcriptional repression by Polycomb repressive complex 1 (PRC1) is the mono-ubiquitination of histone H2A by the combined action of the Posterior sex combs (Psc) and Sex combs extra (Sce) proteins. Here, we report that two ub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ea8d623fdaf4de28b7adb80aabf26b7
https://doi.org/10.1038/emboj.2010.129
https://doi.org/10.1038/emboj.2010.129
Publikováno v:
Genes & Development. 24:933-946
Stem cells are critical for maintaining tissue homeostasis and are commonly governed by their niche microenvironment, although the intrinsic mechanisms controlling their multipotency are poorly understood. Polycomb group (PcG) genes are epigenetic si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16e3c779910590070b6c39d8e8591464
https://doi.org/10.1101/gad.1901510
https://doi.org/10.1101/gad.1901510
Publikováno v:
Genetics. 182:999-1013
The Su(z)2 complex contains Posterior sex combs (Psc) and Suppressor 2 of zeste [Su(z)2], two paralogous genes that likely arose by gene duplication. Psc encodes a Polycomb group protein that functions as a central component of the PRC1 complex, whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9ede18b928909d0ee49ccca173ce3b4
https://doi.org/10.1534/genetics.108.097360
https://doi.org/10.1534/genetics.108.097360
Publikováno v:
Molecular and Cellular Biology. 29:515-525
The Drosophila melanogaster Polycomb group protein Posterior Sex Combs is a component of Polycomb repressive complex 1 and is central to Polycomb group-mediated silencing. A related Polycomb group gene, Suppressor 2 of zeste, is thought to be partial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca401a7207b0495dce3d967410eebf76
https://doi.org/10.1128/mcb.01044-08
https://doi.org/10.1128/mcb.01044-08