Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Poster Abstracts: Identification of Post-Translational Modifications"'
As altered epigenetic regulation is a common feature of cancer, a greater understanding is required of the role of histone post-translational modifications as epigenetic regulators of changes in chromatin structure. Chromatin remodeling may also be i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::3dacd30079f2d285354c53c4fe8b6014
https://europepmc.org/articles/PMC2291944/
https://europepmc.org/articles/PMC2291944/
Autor:
Rauh-Adelmann, C., Gordon, N. F., Graham, J. R., Murphy, C. E., Boucher, J. I., Yen, L. G., Nadler, T. K.
We have developed a sandwich immunoassay method for quantitatively measuring site-specific phosphorylation of multiple proteins and at multiple sites within a protein simultaneously, without the need for multiple, phospho-site-specific detection anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::6080260c6263e9bc8aff43d2c12f51eb
https://europepmc.org/articles/PMC2291900/
https://europepmc.org/articles/PMC2291900/
The evolution of proteomics-based technologies has led to the development of powerful analytical methods for the analysis of post-translational modifications such as phosphorylation. Chemical derivatization strategies that involve beta-elimination an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::c63a69dba9e3d6be2faad6079d09ea3b
https://europepmc.org/articles/PMC2292004/
https://europepmc.org/articles/PMC2292004/
Autor:
Tsuchiya, F., Matsubara, M.
Introduction: Protein phosphorylation is one of the most important post-translational modifications that regulate the function, localization, and binding specificity of target proteins. Specifically, protein phosphorylation works as a switch to turn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::5e419c1ca6fc5216aac5178ea231450a
https://europepmc.org/articles/PMC2291885/
https://europepmc.org/articles/PMC2291885/
The reversible phophorylation of serine, threonine, and tyrosine is one of the most important post-translational modifications involved in various cellular functions. Identification of phophorylation sites by mass spectrometry is challenging due to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::a34ea4835767c06f4df80b94ed71df7a
https://europepmc.org/articles/PMC2291822/
https://europepmc.org/articles/PMC2291822/
Autor:
Buchanan, C. M., Cooper, G. J. S.
Here, we report the isolation and identification of a number of low-molecular-weight proteins (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::b2b8fb691982afae1e214659d2c80f7b
https://europepmc.org/articles/PMC2292003/
https://europepmc.org/articles/PMC2292003/
The Fms-interacting protein (FMIP, MW 78 kDa) acts as a shuttling protein during macrophage differentiation in the human immune system.1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::47aacb3e7f6d5280cc9f6660c1ab7479
https://europepmc.org/articles/PMC2291878/
https://europepmc.org/articles/PMC2291878/
Phosphorylation is one of the most common of the reversible post-translational modifications, but also one of the most challenging. During the last few years, phosphopeptide analysis has benefited from the rapid improvement in biological mass spectro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::38a90b4595bdffa5d1feaa0b2fd774c5
https://europepmc.org/articles/PMC2291992/
https://europepmc.org/articles/PMC2291992/
Protein modification by ubiquitin is an important event that represents a highly versatile means for regulation of protein function. Ubiquitination acts at multiple levels to regulate gene expression, including targeting for degradation, proteolytic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::a828f30de232e599c074a466625166e9
https://europepmc.org/articles/PMC2292063/
https://europepmc.org/articles/PMC2292063/
In order to elucidate the signaling pathway of the human mPR-α protein, a membrane progesterone receptor, a strain of S. cerevisiae overexpressing this protein was generated. Initial global screens using 2D gels, a phospho-specific stain, and tandem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::8a1e032e458049b7293db04a3a085c9e
https://europepmc.org/articles/PMC2291982/
https://europepmc.org/articles/PMC2291982/