Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Poster Abstracts: Bioinfomatics"'
A number of protein and peptide identification software tools based on MS data are available to the proteomics researchers. They all share a common functionality: they process MS data and present in their output peptides and proteins that best match
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d8986c01e4fd590b02c0a82db978700d
https://europepmc.org/articles/PMC2291883/
https://europepmc.org/articles/PMC2291883/
Autor:
Li, G., Golick, D., Dyson, B., Silva, J. C., Liu, H., Vissers, J. P. C., Gebler, J. C., Gorenstein, M. V., Geromanos, S. J.
A novel, “Ion Accounting” algorithm has been developed for protein identification using time-resolved, LC-MSE data from 1D and 2D LC-MS experiments. The data from a 1D LC-MS analysis generate a series of precursor-product tables that are initiall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::87285081b220d48eb6db7c0f46e77112
https://europepmc.org/articles/PMC2292061/
https://europepmc.org/articles/PMC2292061/
The Mouse Genome Informatics (MGI; http://www.informatics.jax.org/) database integrates genetic and genomic data with the primary mission of facilitating the use of the mouse as a model system for understanding human biology and disease processes. MG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::12ecab510ea0d593a7096c122862f67e
https://europepmc.org/articles/PMC2291881/
https://europepmc.org/articles/PMC2291881/
Autor:
Chamrad, D. C., Blueggel, M., Koerting, G., Glandorf, J., Vagts, J., Hufnagel, P., Thiele, H.
Proteomics inherently deals with huge amounts of data. Current mass spectrometers acquire hundreds of thousands of spectra within a single project. Thus, data management and data analysis are a challenge. We have developed a software platform (Protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::fe6c0ccca90a071932e2b27d7705cb8d
https://europepmc.org/articles/PMC2291826/
https://europepmc.org/articles/PMC2291826/
Autor:
Sadygov, R. G., Zabrouskov, V.
The work describes modifications to and application of Sequest database search algorithms to identify peptides from their high mass accuracy tandem mass spectra. We show the technical problems encountered when attempting to use high mass accuracy dat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::41b93e6cb8feb0ac94fcb65b42743844
https://europepmc.org/articles/PMC2292005/
https://europepmc.org/articles/PMC2292005/
In the course of a full-scale proteomics experiment, the handling of the data as well as the retrieval of the relevant information from the results is a major challenge due to the massive amount of generated data (gel images, chromatograms, and spect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::df600d222feb288d28c1832aa2a201f2
https://europepmc.org/articles/PMC2291897/
https://europepmc.org/articles/PMC2291897/
We analyzed mRNAs regulated during differentiation of rat neural stem cells using the ABI1700 microarray platform. This microarray, while technically advanced, suffers from the difficulty of integrating hybridization results into public databases for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::7dbeb7f10927c6f2783d38b3289da631
https://europepmc.org/articles/PMC2291861/
https://europepmc.org/articles/PMC2291861/
The application of multireaction monitoring (MRM) for proteomics analysis is a quite recent development. The sensitivity of four orders of magnitude, reproducibility, and the option of quantification as well as high throughput make MRM a valuable too
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::5fc90435187e5c28eaf1497fb1cf1845
https://europepmc.org/articles/PMC2291962/
https://europepmc.org/articles/PMC2291962/
Proteomic analyses typically produce massive amounts of mass spectrometric data, which are analyzed in an automated way by database search engines for retrieval of peptide sequences and subsequent inference on the corresponding protein sequences. How
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::d79142b5ceaace4a39328e6e930dbd9e
https://europepmc.org/articles/PMC2291870/
https://europepmc.org/articles/PMC2291870/
Autor:
Falkner, J. A., Andrews, P. C.
The number, size, and format variation for proteomics data files (both raw and processed), annotation, as well as challenges in designing a robust data repository are some of the major factors inhibiting public dissemination of proteomics data. Shari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::400cf21ba0d31c2aab824d43a3394f56
https://europepmc.org/articles/PMC2292060/
https://europepmc.org/articles/PMC2292060/