Zobrazeno 1 - 10
of 823
pro vyhledávání: '"Post transplant cyclophosphamide"'
Autor:
Christopher Graham, Mark Litzow
Publikováno v:
Hematology, Vol 29, Iss 1 (2024)
Introduction The likelihood of finding HLA-matched unrelated donors for rare HLA types and non-white European ancestry continues to be a challenge with less than a 70% chance of finding a full match. Mismatched transplants continue to have high rates
Externí odkaz:
https://doaj.org/article/87a988b3f2654840adde5a420f289cf1
Publikováno v:
Hematology, Vol 29, Iss 1 (2024)
Background One major limitation for broader applicability of allogeneic hematopoietic cell transplantation (allo-HCT) in the past was the lack of HLA-matched histocompatible donors. Preclinical mouse studies using T-cell depleted haploidentical graft
Externí odkaz:
https://doaj.org/article/0d5342cfd0f34d9eab336b1de19c2b48
Autor:
Dong Hyun Kim, Dong-Yeop Shin, Youngil Koh, Inho Kim, Sung-Soo Yoon, Ja Min Byun, Junshik Hong
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract This study aimed to assess the efficacy of dual T-cell suppression using individually tailored doses of antithymocyte globulin (ATG) and attenuated dose of post-transplant cyclophosphamide (PTCy) in haploidentical hematopoietic stem cell tra
Externí odkaz:
https://doaj.org/article/9e6b3a6008c745668dcce82783a22d7a
Autor:
Hirohisa Nakamae
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Post-transplant cyclophosphamide (PTCy) is becoming the standard prophylaxis for graft-versus-host disease (GVHD) in HLA-haploidentical allogeneic hematopoietic cell transplantation (allo-HCT) and in HLA-matched allo-HCT. Immune reconstitution in the
Externí odkaz:
https://doaj.org/article/49ccd20adfd947daa15da51f77739770
Autor:
Alexandra Ionete, Alexandru Bardas, Zsofia Varady, Madalina Vasilica, Orsolya Szegedi, Daniel Coriu
Publikováno v:
Diseases, Vol 12, Iss 9, p 210 (2024)
Adult T-cell Leukemia/Lymphoma (ATLL) is a rare but aggressive malignancy associated with the human T-cell lymphotropic virus type 1 (HTLV-1). ATLL is a challenging malignancy characterized by its aggressive nature and poor prognosis. Despite advance
Externí odkaz:
https://doaj.org/article/bf7cdfe4e45a408da2b06b1a0b7d685f
Autor:
Naoki Okada, Ryusuke Yamamoto, Hayato Maruoka, Mayuko Himeno, Nobuhiro Hiramoto, Takayuki Ishikawa
Publikováno v:
Case Reports in Oncology, Vol 16, Iss 1, Pp 604-612 (2023)
T-cell prolymphocytic leukemia (T-PLL) is a rare aggressive disease with a poor prognosis. Allogeneic stem cell transplantation (allo-SCT) followed by alemtuzumab administration is the most promising treatment for T-PLL but is associated with a high
Externí odkaz:
https://doaj.org/article/46dc5f994c1a435e8bf84e4556da82fd
Autor:
Chloe Sligar, Ellie Reilly, Peter Cuthbertson, Kara L Vine, Katrina M Bird, Amal Elhage, Stephen I Alexander, Ronald Sluyter, Debbie Watson
Publikováno v:
Clinical & Translational Immunology, Vol 13, Iss 3, Pp n/a-n/a (2024)
Abstract Objectives Donor haematopoietic stem cell transplantation treats leukaemia by inducing graft‐versus‐leukaemia (GVL) immunity. However, this benefit is often mitigated by graft‐versus‐host disease (GVHD), which is reduced by post‐tr
Externí odkaz:
https://doaj.org/article/ff78bb68913b4966b944916c5799b624
Autor:
Tahereh Bakhtiari, Mohammad Ahmadvand, Marjan Yaghmaie, Alireza Sadeghi, Seied Asadollah Mousavi, Tahereh Rostami, Mazdak Ganjalikhani-Hakemi
Publikováno v:
BMC Immunology, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Background KIR/HLA mismatch in hematopoietic stem cell transplantation (HSCT), particularly in patients with acute myeloid leukemia (AML), was related to decreased recurrence rates, improved engraftment, and a reduction in graft-versus-host
Externí odkaz:
https://doaj.org/article/6a112b111e154687bb440c2aa30301fb
Autor:
Yu Lung Lau, Andrew Gennery
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/617343e7c3c24ed09a3d81a2a10feacf
Autor:
Frédéric Baron, Myriam Labopin, Johanna Tischer, Anna Maria Raiola, Jan Vydra, Didier Blaise, Patrizia Chiusolo, Friedrich Stölzel, Renato Fanin, Patrice Chevallier, Arnon Nagler, Fabio Ciceri, Mohamad Mohty
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-5 (2023)
Abstract The association between graft-versus-host disease (GVHD) occurrence and acute myeloid leukemia (AML) relapse in patients treated with HLA-haploidentical allogeneic hematopoietic stem cell transplantation (Haplo-HCT) with post-transplant cycl
Externí odkaz:
https://doaj.org/article/e846149530f94e79a96d37ec3420549b