A method to study extracellular vesicles secreted in vitro by cultured cells with minimum sample processing and extracellular vesicle loss

Autor: Kadam, Anissa Viveiros, Aja M. Rieger, John Monyror, Simonetta Sipione, Luis Carlos Morales, Posse de Chaves E, Desmond Pink

Extracellular vesicles (EVs) are involved in a multitude of physiological functions and play important roles in health and disease. The study of EV secretion and EV characterization remains challenging due to the small size of these particles, a lack

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8621c92963d4688a7008df25515cf8a6
https://doi.org/10.1101/2021.06.18.447964

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Endosomal-Lysosomal Cholesterol Sequestration by U18666A Differentially Regulates Amyloid Precursor Protein (APP) Metabolism in Normal and APP-Overexpressing Cells.

Autor: Chung J; Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, Alberta, Canada.; Department of Psychiatry, University of Alberta, Edmonton, Alberta, Canada., Phukan G; Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, Alberta, Canada.; Department of Medicine, University of Alberta, Edmonton, Alberta, Canada., Vergote D; Faculté Saint-Jean, University of Alberta, Edmonton, Alberta, Canada., Mohamed A; Department of Pharmacology, University of Alberta, Edmonton, Alberta, Canada., Maulik M; Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, Alberta, Canada., Stahn M; Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, Alberta, Canada., Andrew RJ; Departments of Neurobiology, Neurology, and Pathology, The University of Chicago, Chicago, Illinois, USA., Thinakaran G; Departments of Neurobiology, Neurology, and Pathology, The University of Chicago, Chicago, Illinois, USA., Posse de Chaves E; Department of Pharmacology, University of Alberta, Edmonton, Alberta, Canada., Kar S; Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, Alberta, Canada skar@ualberta.ca.; Department of Psychiatry, University of Alberta, Edmonton, Alberta, Canada.; Faculté Saint-Jean, University of Alberta, Edmonton, Alberta, Canada.

Publikováno v: Molecular and cellular biology [Mol Cell Biol] 2018 May 15; Vol. 38 (11). Date of Electronic Publication: 2018 May 15 (Print Publication: 2018).