Mapping interactions of calmodulin and neuronal NO synthase by crosslinking and mass spectrometry

Autor: Felker, Dana, Lee, Kanghyun, Pospiech, Thomas H., Morishima, Yoshihiro, Zhang, Haoming, Lau, Miranda, Southworth, Daniel R., Osawa, Yoichi

Publikováno v: In Journal of Biological Chemistry January 2024 300(1)

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms

Autor: Gordon, David E., Hiatt, Joseph, Bouhaddou, Mehdi, Rezelj, Veronica V., Ulferts, Svenja, Braberg, Hannes, Jureka, Alexander S., Obernier, Kirsten, Guo, Jeffrey Z., Batra, Jyoti, Kaake, Robyn M., Weckstein, Andrew R., Owens, Tristan W., Gupta, Meghna, Pourmal, Sergei, Titus, Erron W., Cakir, Merve, Soucheray, Margaret, McGregor, Michael, Cakir, Zeynep, Jang, Gwendolyn, O’Meara, Matthew J., Tummino, Tia A., Zhang, Ziyang, Foussard, Helene, Rojc, Ajda, Zhou, Yuan, Kuchenov, Dmitry, Hüttenhain, Ruth, Xu, Jiewei, Eckhardt, Manon, Swaney, Danielle L., Fabius, Jacqueline M., Ummadi, Manisha, Tutuncuoglu, Beril, Rathore, Ujjwal, Modak, Maya, Haas, Paige, Haas, Kelsey M., Naing, Zun Zar Chi, Pulido, Ernst H., Shi, Ying, Barrio-Hernandez, Inigo, Memon, Danish, Petsalaki, Eirini, Dunham, Alistair, Marrero, Miguel Correa, Burke, David, Koh, Cassandra, Vallet, Thomas, Silvas, Jesus A., Azumaya, Caleigh M., Billesbølle, Christian, Brilot, Axel F., Campbell, Melody G., Diallo, Amy, Dickinson, Miles Sasha, Diwanji, Devan, Herrera, Nadia, Hoppe, Nick, Kratochvil, Huong T., Liu, Yanxin, Merz, Gregory E., Moritz, Michelle, Nguyen, Henry C., Nowotny, Carlos, Puchades, Cristina, Rizo, Alexandrea N., Schulze-Gahmen, Ursula, Smith, Amber M., Sun, Ming, Young, Iris D., Zhao, Jianhua, Asarnow, Daniel, Biel, Justin, Bowen, Alisa, Braxton, Julian R., Chen, Jen, Chio, Cynthia M., Chio, Un Seng, Deshpande, Ishan, Doan, Loan, Faust, Bryan, Flores, Sebastian, Jin, Mingliang, Kim, Kate, Lam, Victor L., Li, Fei, Li, Junrui, Li, Yen-Li, Li, Yang, Liu, Xi, Lo, Megan, Lopez, Kyle E., Melo, Arthur A., Moss, Frank R., Nguyen, Phuong, Paulino, Joana, Pawar, Komal Ishwar, Peters, Jessica K., Pospiech, Thomas H., Safari, Maliheh, Sangwan, Smriti, Schaefer, Kaitlin, Thomas, Paul V., Thwin, Aye C., Trenker, Raphael, Tse, Eric, Tsui, Tsz Kin Martin, Wang, Feng, Whitis, Natalie, Yu, Zanlin, Zhang, Kaihua, Zhang, Yang, Zhou, Fengbo, Saltzberg, Daniel, Hodder, Anthony J., Shun-Shion, Amber S., Williams, Daniel M., White, Kris M., Rosales, Romel, Kehrer, Thomas, Miorin, Lisa, Moreno, Elena, Patel, Arvind H., Rihn, Suzannah, Khalid, Mir M., Vallejo-Gracia, Albert, Fozouni, Parinaz, Simoneau, Camille R., Roth, Theodore L., Wu, David, Karim, Mohd Anisul, Ghoussaini, Maya, Dunham, Ian, Berardi, Francesco, Weigang, Sebastian, Chazal, Maxime, Park, Jisoo, Logue, James, McGrath, Marisa, Weston, Stuart, Haupt, Robert, Hastie, C. James, Elliott, Matthew, Brown, Fiona, Burness, Kerry A., Reid, Elaine, Dorward, Mark, Johnson, Clare, Wilkinson, Stuart G., Geyer, Anna, Giesel, Daniel M., Baillie, Carla, Raggett, Samantha, Leech, Hannah, Toth, Rachel, Goodman, Nicola, Keough, Kathleen C., Lind, Abigail L., Klesh, Reyna J., Hemphill, Kafi R., Carlson-Stevermer, Jared, Oki, Jennifer, Holden, Kevin, Maures, Travis, Pollard, Katherine S., Sali, Andrej, Agard, David A., Cheng, Yifan, Fraser, James S., Frost, Adam, Jura, Natalia, Kortemme, Tanja, Manglik, Aashish, Southworth, Daniel R., Stroud, Robert M., Alessi, Dario R., Davies, Paul, Frieman, Matthew B., Ideker, Trey, Abate, Carmen, Jouvenet, Nolwenn, Kochs, Georg, Shoichet, Brian, Ott, Melanie, Palmarini, Massimo, Shokat, Kevan M., García-Sastre, Adolfo, Rassen, Jeremy A., Grosse, Robert, Rosenberg, Oren S., Verba, Kliment A., Basler, Christopher F., Vignuzzi, Marco, Peden, Andrew A., Beltrao, Pedro, Krogan, Nevan J., Trinidad, Donovan, Damas, Joana, Hughes, Graham M., Painter, Corrie A., Persky, Nicole S., Corbo, Marco, Kirilenko, Bodgan, Hiller, Michael, Koepfli, Klaus-Peter, Kaplow, Irene, Wirthlin, Morgan, Pfenning, Andreas R., Zhao, Huabin, Genereux, Diane P., Swofford, Ross, Lind, Abigail, Ryderq, Oliver A., Nweeia, Martin T., Meadows, Jennifer, Dong, Michael, Wallerman, Ola, Marinescu, Vikki, Lindblad-Toh, Kerstin, Ray, David A., Power, Sarahjane, Teeling, Emma C., Chauhan, Gaurav, Li, Shirley Xue, Karlsson, Elinor K., Lewin, Harris A.

Publikováno v: Science
Science, American Association for the Advancement of Science, 2020, 370 (6521), pp.eabe9403. ⟨10.1126/science.abe9403⟩
Science, 2020, 370 (6521), pp.eabe9403. ⟨10.1126/science.abe9403⟩

INTRODUCTION The emergence of three lethal coronaviruses in Jennifer Meadows, Michael Dong, Ola Wallerman, Vikki Marinescu & Kerstin Lindblad-Toh ingår i gruppen Zoonomia Consortium

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70a2ec1706b39252a68e729af326d9d2

Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps.

Autor: Remesh, Soumya G.^1,2 (AUTHOR), Merz, Gregory E.² (AUTHOR), Brilot, Axel F.² (AUTHOR), Chio, Un Seng² (AUTHOR), Rizo, Alexandrea N.² (AUTHOR), Pospiech, Thomas H.² (AUTHOR), Lui, Irene¹ (AUTHOR), Laurie, Mathew T.³ (AUTHOR), Glasgow, Jeff¹ (AUTHOR), Le, Chau Q.¹ (AUTHOR), Zhang, Yun¹ (AUTHOR), Diwanji, Devan² (AUTHOR), Hernandez, Evelyn² (AUTHOR), Lopez, Jocelyne² (AUTHOR), Mehmood, Hevatib² (AUTHOR), Pawar, Komal Ishwar² (AUTHOR), Pourmal, Sergei² (AUTHOR), Smith, Amber M.² (AUTHOR), Zhou, Fengbo² (AUTHOR), DeRisi, Joseph^3,4 (AUTHOR)

Publikováno v: Structure. Mar2023, Vol. 31 Issue 3, p253-253. 1p.

CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.

Autor: Gupta M; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Azumaya CM; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Moritz M; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Pourmal S; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Diallo A; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Merz GE; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Jang G; Quantitative Biosciences Institute (QBI) COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA.; QBI, University of California, San Francisco, CA 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA.; J. David Gladstone Institutes, San Francisco, CA 94158, USA., Bouhaddou M; Quantitative Biosciences Institute (QBI) COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA.; QBI, University of California, San Francisco, CA 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA.; J. David Gladstone Institutes, San Francisco, CA 94158, USA., Fossati A; Quantitative Biosciences Institute (QBI) COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA.; QBI, University of California, San Francisco, CA 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA.; J. David Gladstone Institutes, San Francisco, CA 94158, USA., Brilot AF; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Diwanji D; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Hernandez E; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Herrera N; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Kratochvil HT; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Lam VL; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Li F; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Li Y; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Nguyen HC; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Nowotny C; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Owens TW; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Peters JK; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Rizo AN; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Schulze-Gahmen U; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Smith AM; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Young ID; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Yu Z; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Asarnow D; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Billesbølle C; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Campbell MG; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA.; Current affiliation: Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA., Chen J; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Chen KH; Quantitative Biosciences Institute (QBI) COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA.; QBI, University of California, San Francisco, CA 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA.; J. David Gladstone Institutes, San Francisco, CA 94158, USA., Chio US; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Dickinson MS; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Doan L; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Jin M; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Kim K; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Li J; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Li YL; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Linossi E; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Liu Y; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Lo M; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Lopez J; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Lopez KE; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Mancino A; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Moss FR 3rd; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Paul MD; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Pawar KI; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Pelin A; Quantitative Biosciences Institute (QBI) COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA.; QBI, University of California, San Francisco, CA 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA.; J. David Gladstone Institutes, San Francisco, CA 94158, USA., Pospiech TH Jr; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Puchades C; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Remesh SG; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Safari M; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Schaefer K; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Sun M; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA.; Current affiliation: Beam Therapeutics, Cambridge, MA 02139, USA., Tabios MC; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Thwin AC; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Titus EW; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Trenker R; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Tse E; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Tsui TKM; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Wang F; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Zhang K; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Zhang Y; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Zhao J; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Zhou F; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA., Zhou Y; Quantitative Biosciences Institute (QBI) COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA.; QBI, University of California, San Francisco, CA 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA.; J. David Gladstone Institutes, San Francisco, CA 94158, USA., Zuliani-Alvarez L; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA.; Quantitative Biosciences Institute (QBI) COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA.; QBI, University of California, San Francisco, CA 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA.; J. David Gladstone Institutes, San Francisco, CA 94158, USA., Agard DA; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA.; Quantitative Biosciences Institute (QBI) COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA.; QBI, University of California, San Francisco, CA 94158, USA.; Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94158, USA., Cheng Y; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA.; Quantitative Biosciences Institute (QBI) COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA.; QBI, University of California, San Francisco, CA 94158, USA.; Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94158, USA.; Howard Hughes Medical Institute, San Francisco, CA 94158, USA., Fraser JS; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA.; Quantitative Biosciences Institute (QBI) COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA.; QBI, University of California, San Francisco, CA 94158, USA.; Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94158, USA., Jura N; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA.; Quantitative Biosciences Institute (QBI) COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA.; QBI, University of California, San Francisco, CA 94158, USA.; Cardiovascular Research Institute, University of California, San Francisco, CA 94158, USA., Kortemme T; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA.; Quantitative Biosciences Institute (QBI) COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA.; QBI, University of California, San Francisco, CA 94158, USA.; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, CA 94158, USA.; The University of California, Berkeley-University of California, San Francisco Graduate Program in Bioengineering, University of California, San Francisco, CA 94158, USA., Manglik A; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA.; Quantitative Biosciences Institute (QBI) COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA.; QBI, University of California, San Francisco, CA 94158, USA.; Department of Pharmaceutical Chemistry, University of California, San Francisco, CA 94158, USA., Southworth DR; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA.; Quantitative Biosciences Institute (QBI) COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA.; QBI, University of California, San Francisco, CA 94158, USA.; Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94158, USA., Stroud RM; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA.; Quantitative Biosciences Institute (QBI) COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA.; QBI, University of California, San Francisco, CA 94158, USA.; Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94158, USA., Swaney DL; Quantitative Biosciences Institute (QBI) COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA.; QBI, University of California, San Francisco, CA 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA.; J. David Gladstone Institutes, San Francisco, CA 94158, USA., Krogan NJ; Quantitative Biosciences Institute (QBI) COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA.; QBI, University of California, San Francisco, CA 94158, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA.; J. David Gladstone Institutes, San Francisco, CA 94158, USA.; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Frost A; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA.; Quantitative Biosciences Institute (QBI) COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA.; QBI, University of California, San Francisco, CA 94158, USA.; Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94158, USA.; Chan-Zuckerberg Biohub, San Francisco, CA 94158, USA., Rosenberg OS; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA.; Quantitative Biosciences Institute (QBI) COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA.; QBI, University of California, San Francisco, CA 94158, USA.; Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94158, USA.; Chan-Zuckerberg Biohub, San Francisco, CA 94158, USA.; Department of Medicine, University of California, San Francisco, CA 94143, USA., Verba KA; QBI Coronavirus Research Group Structural Biology Consortium, University of California, San Francisco, CA 94158, USA.; Quantitative Biosciences Institute (QBI) COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA.; QBI, University of California, San Francisco, CA 94158, USA.; Department of Pharmaceutical Chemistry, University of California, San Francisco, CA 94158, USA.

Publikováno v: Research square [Res Sq] 2021 May 19. Date of Electronic Publication: 2021 May 19.