Zobrazeno 1 - 10
of 324
pro vyhledávání: '"Positive-strand RNA virus"'
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Infection by flaviviruses leads to dramatic remodeling of the endoplasmic reticulum (ER). Viral replication occurs within virus-induced vesicular invaginations in the ER membrane. A hallmark of flavivirus infection is expansion of the ER membrane whi
Externí odkaz:
https://doaj.org/article/e985647e65024424814e1c24746654c3
Autor:
Karoline Metzger, Cyrine Bentaleb, Kévin Hervouet, Virginie Alexandre, Claire Montpellier, Jean-Michel Saliou, Martin Ferrié, Charline Camuzet, Yves Rouillé, Cécile Lecoeur, Jean Dubuisson, Laurence Cocquerel, Cécile-Marie Aliouat-Denis
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Hepatitis E virus (HEV) is the major cause of acute hepatitis worldwide. HEV is a positive-sense RNA virus expressing three open reading frames (ORFs). ORF1 encodes the ORF1 non–structural polyprotein, the viral replicase which transcribes the full
Externí odkaz:
https://doaj.org/article/aacad7b61099488d88253d8395cff855
Publikováno v:
Viruses, Vol 15, Iss 2, p 275 (2023)
Flaviviruses represent a large group of globally significant, insect-borne pathogens. For many of these viruses, there is a lack of antivirals and vaccines. Thus, there is a need to continue the development of tools to further advance our efforts to
Externí odkaz:
https://doaj.org/article/eda290a7b70b49058f41745f1f8d72ce
Autor:
Johan A. den Boon, Hong Zhan, Nuruddin Unchwaniwala, Mark Horswill, Kailey Slavik, Janice Pennington, Amanda Navine, Paul Ahlquist
Publikováno v:
Viruses, Vol 14, Iss 12, p 2711 (2022)
Positive-strand RNA virus RNA genome replication occurs in membrane-associated RNA replication complexes (RCs). Nodavirus RCs are outer mitochondrial membrane invaginations whose necked openings to the cytosol are “crowned” by a 12-fold symmetric
Externí odkaz:
https://doaj.org/article/7d63f1c257934b36a62f4f9c5ac7751a
Publikováno v:
Viruses, Vol 14, Iss 12, p 2615 (2022)
The 3′ untranslated regions (UTRs) of positive-strand RNA plant viruses commonly contain elements that promote viral replication and translation. The ~700 nt 3′UTR of umbravirus pea enation mosaic virus 2 (PEMV2) contains three 3′ cap-independe
Externí odkaz:
https://doaj.org/article/076b05cbad2444f0ae26f3689c0b6faf
Akademický článek
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Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2017 Feb . 114(7), E1282-E1290.
Externí odkaz:
https://www.jstor.org/stable/26479438
Akademický článek
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Autor:
Hengxia Jia, Peng Gong
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
The RNA-dependent RNA polymerases (RdRPs) encoded by the RNA viruses are a unique class of nucleic acid polymerases. Each viral RdRP contains a 500–600 residue catalytic module with palm, fingers, and thumb domains forming an encircled human right
Externí odkaz:
https://doaj.org/article/141d0335649c4631934044b15c7c6bd4
Autor:
Zhenlu Zhang, Guijuan He, Natalie A. Filipowicz, Glenn Randall, George A. Belov, Benjamin G. Kopek, Xiaofeng Wang
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Membrane association is a hallmark of the genome replication of positive-strand RNA viruses [(+)RNA viruses]. All well-studied (+)RNA viruses remodel host membranes and lipid metabolism through orchestrated virus-host interactions to create a suitabl
Externí odkaz:
https://doaj.org/article/d3da6809f2f24909b8d31bebde299d65