Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Positive inotropism"'
Publikováno v:
4.1 Clinical respiratory physiology, exercise and functional imaging.
Introduction: The apelin-APLNR system mediates positive inotropism and vasodilatation in the cardiolvascular vascular system. The complex regulatorymechanism of apelin-APJ together with its physiologic effects suggest that the levels of apelin may ch
Autor:
Javier Bordallo, Manuel Sánchez, Agustín Hidalgo, Rosario Cortina, Lorena Secades, Lucía Velasco
Publikováno v:
Pharmacology. 70:118-122
Pharmacological concentrations of androgens are known to elicit a rapid positive inotropism in isolated left atrium of male rats. Upon short-term exposure to androgens, an increase in intracellular cAMP levels has been observed, though delayed with r
Autor:
Luciana Siqueira Amorim, Manassés C. Fonteles, Cláudia F. Santos, Victor Martins Gomes, Nilberto R.F. Nascimento
Publikováno v:
The FASEB Journal. 27
Publikováno v:
International journal of cardiology. 168(2)
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 4:2585-2588
In 5-methyl-dihydropyridazinones, a stereoselectivity is observed only with respect to the phosphodiesterase III-inhibition. The (−)-enantiomers are very strong inhibitors whereas their (+)-counterparts exhibit only a weak activity. In the case of
Akademický článek
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Autor:
Monica Montopoli, Paola Dorigo, Guglielmina Froldi, Miriam Zanetti, Laura Caparrotta, Giampietro Galzignato
Publikováno v:
Pharmacology. 73(3)
Uridine 5′-triphosphate (UTP) and adenosine 5′-triphosphate (ATP) induce biphasic inotropic effects: first a decrease and then an increase in contractile tension were observed in isolated rat myocardial tissues. Inotropic effects were higher in a
Akademický článek
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Autor:
Guglielmina Froldi, Pier Andrea Borea, Eugenio Ragazzi, Laura Caparrotta, Alessandro Chinellato, Katia Varani
Positive inotropic effects of ATP and UTP (1 microM - 1mM) were studied in isolated rat and guinea pig cardiac tissues. The potency order obtained was ATPUTP in both species, suggesting possible interaction with P2X-purinoceptors. Binding studies usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02bcd84f70afae7ab2db48efc85fb28a
http://hdl.handle.net/11392/1197906
http://hdl.handle.net/11392/1197906
Publikováno v:
Heart and vessels. 9(3)
Ventricular ejection is known to have dual effects on the end-systolic pressure: the ejecting deactivation by a relatively large ejection against a low afterload versus the ejecting activation by a relatively small ejection against a high afterload.