Zobrazeno 1 - 10
of 371
pro vyhledávání: '"Positive inotropic effect"'
Autor:
Daniel Mota-Rojas, Dina Villanueva-García, Ismael Hernández-Ávalos, Alejandro Casas-Alvarado, Adriana Domínguez-Oliva, Karina Lezama-García, Agatha Miranda-Cortés, Julio Martínez-Burnes
Publikováno v:
Animals, Vol 13, Iss 11, p 1769 (2023)
Caffeine is widely used to improve neonatal health in animals with low vitality. Due to its pharmacokinetics and pharmacodynamics, caffeine stimulates the cardiorespiratory system by antagonism of adenosine receptors and alteration in Ca+2 ion channe
Externí odkaz:
https://doaj.org/article/07705c19d1ce4dea8dd6595f7be4c084
Akademický článek
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Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Previous studies showed that berberine, an alkaloid from Coptis Chinensis Franch, might exert a positive inotropic effect on the heart. However, the underlying mechanisms were unclear. Here, we reported that berberine at 10–20 µM increased the lef
Externí odkaz:
https://doaj.org/article/dc98198abce4419eb986f8c220655ab9
Autor:
R. Chaban, A. Kornberger, N. Branski, K. Buschmann, N. Stumpf, A. Beiras-Fernandez, C.F. Vahl
Publikováno v:
BMC Cardiovascular Disorders, Vol 17, Iss 1, Pp 1-8 (2017)
Abstract Background Our study aimed to evaluate changes in the contractile behavior of human myocardium after exposure to caffeine and taurine, the main active ingredients of energy drinks (EDs), and to evaluate whether taurine exhibits any inotropic
Externí odkaz:
https://doaj.org/article/a278e04bb5804e87a935442240acffbb
Autor:
Mitsui-Saitoh, Kumiko, Aoyagi, Yutaka, Hitotsuyanagi, Yukio, Takeya, Koichi, Sakai, Junichi, Hotta, Yoshihiro
Publikováno v:
名古屋学院大学論集 人文・自然科学篇 = THE NAGOYA GAKUIN DAIGAKU RONSHU; Journal of Nagoya Gakuin University; HUMANITIES and NATURAL SCIENCES. 57(2):29-35
A plant in the Lamiaceae family, rosemary ( Rosmarinus officinalis ) is a perennial shrub native to the Mediterranean region. The current study used right atrial specimens from guinea pigs to assess the biological activity of 3 catechol diterpenes wi
Autor:
Mitsui-Saitoh, Kumiko, Aoyagi, Yutaka, Hitotsuyanagi, Yukio, Takeya, Koichi, Ming-Yu, Gui, Yong-Ri, Jin, Xu-Wen, LI, Sakai, Junichi, Hotta, Yoshihiro
Publikováno v:
名古屋学院大学論集 人文・自然科学篇 = THE NAGOYA GAKUIN DAIGAKU RONSHU; Journal of Nagoya Gakuin University; HUMANITIES and NATURAL SCIENCES. 57(2):19-27
The medicinal plant Rabdosia excisa in the Lamiaceae family is found in Northeastern China and is used to treat a fever due to a cold, mastitis, arthralgia, and bruises[1]. A previous study reported that an aqueous extract from that plant yielded ent
Publikováno v:
Molecules, Vol 18, Iss 4, Pp 4561-4572 (2013)
Liguzinediol (LZDO) ester prodrugs 3–5 were synthesized and evaluated in vitro and in vivo for their potential use in prolonging the half-life of the parent drug LZDO (1a) in vivo. Prodrugs 3–5 were found to display a potent positive inotropic ef
Externí odkaz:
https://doaj.org/article/0b21c6ed33ae425ba3cee20a8df7b7a5
Autor:
Norbert Nagy, Kaisa Syrjänen, Piet Finckenberg, Gerd Wohlfahrt, Jouko Levijoki, Tuula Koskelainen, A. Koivisto, András Varró, Paul E. Miller, László Virág, Najah Abi-Gerges, Leena Otsomaa, Eero Mervaala, Andrea Ghetti, Hugh Chapman, Saara‐Elisa Peltokorpi, Aira Heikkilä, Norbert Jost, Guy Page, Julius Gy. Papp, Zsófia Kohajda
Publikováno v:
British Journal of Pharmacology
BACKGROUND AND PURPOSE: The lack of selective sodium-calcium exchanger (NCX) inhibitors has hampered the exploration of physiological and pathophysiological roles of cardiac NCX 1.1. We aimed to discover more potent and selective drug like NCX 1.1 in
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Previous studies showed that berberine, an alkaloid from Coptis Chinensis Franch, might exert a positive inotropic effect on the heart. However, the underlying mechanisms were unclear. Here, we reported that berberine at 10-20 µM increased the left