DNMT3A Harboring Leukemia-Associated Mutations Directs Sensitivity to DNA Damage at Replication Forks.

Autor: Venugopal K; Department of Pharmacology and Therapeutics, University of Florida College of Medicine, Gainesville, Florida., Feng Y; Department of Pharmacology and Therapeutics, University of Florida College of Medicine, Gainesville, Florida., Nowialis P; Department of Anatomy and Cell Biology, University of Florida College of Medicine, Gainesville, Florida., Xu H; Department of Pediatrics, Division of Infectious Diseases, University of Florida College of Medicine, Gainesville, Florida., Shabashvili DE; Department of Pharmacology and Therapeutics, University of Florida College of Medicine, Gainesville, Florida., Berntsen CM; Department of Pharmacology and Therapeutics, University of Florida College of Medicine, Gainesville, Florida., Kaur P; Department of Pharmacology and Therapeutics, University of Florida College of Medicine, Gainesville, Florida., Krajcik KI; Department of Pharmacology and Therapeutics, University of Florida College of Medicine, Gainesville, Florida., Taragjini C; Department of Pharmacology and Therapeutics, University of Florida College of Medicine, Gainesville, Florida., Zaroogian Z; Department of Pharmacology and Therapeutics, University of Florida College of Medicine, Gainesville, Florida., Casellas Román HL; Department of Pharmacology and Therapeutics, University of Florida College of Medicine, Gainesville, Florida., Posada LM; Department of Pharmacology and Therapeutics, University of Florida College of Medicine, Gainesville, Florida., Gunaratne C; Department of Pharmacology and Therapeutics, University of Florida College of Medicine, Gainesville, Florida., Li J; Department of Medicine, Division of Hematology/ Oncology, University of Florida College of Medicine, Gainesville, Florida., Dupéré-Richer D; Department of Medicine, Division of Hematology/ Oncology, University of Florida College of Medicine, Gainesville, Florida., Bennett RL; Department of Medicine, Division of Hematology/ Oncology, University of Florida College of Medicine, Gainesville, Florida.; University of Florida Health Cancer Center, Gainesville, Florida., Pondugula S; Department of Pharmacology and Therapeutics, University of Florida College of Medicine, Gainesville, Florida., Riva A; University of Florida Health Cancer Center, Gainesville, Florida.; Bioinformatics Core, Interdisciplinary Center for Biotechnology Research, University of Florida, Gainesville, Florida., Cogle CR; Department of Medicine, Division of Hematology/ Oncology, University of Florida College of Medicine, Gainesville, Florida.; University of Florida Health Cancer Center, Gainesville, Florida., Opavsky R; Department of Anatomy and Cell Biology, University of Florida College of Medicine, Gainesville, Florida.; University of Florida Health Cancer Center, Gainesville, Florida., Law BK; Department of Pharmacology and Therapeutics, University of Florida College of Medicine, Gainesville, Florida.; University of Florida Health Cancer Center, Gainesville, Florida., Bhaduri-McIntosh S; Department of Pediatrics, Division of Infectious Diseases, University of Florida College of Medicine, Gainesville, Florida.; University of Florida Health Cancer Center, Gainesville, Florida.; Department of Molecular Genetics and Microbiology, University of Florida College of Medicine, Gainesville, Florida., Kubicek S; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Staber PB; Division of Hematology and Hemostaseology, Department of Medicine 1, Comprehensive Cancer Center Vienna, Medical University of Vienna, Vienna, Austria., Licht JD; Department of Medicine, Division of Hematology/ Oncology, University of Florida College of Medicine, Gainesville, Florida.; University of Florida Health Cancer Center, Gainesville, Florida., Bird JE; Department of Pharmacology and Therapeutics, University of Florida College of Medicine, Gainesville, Florida., Guryanova OA; Department of Pharmacology and Therapeutics, University of Florida College of Medicine, Gainesville, Florida.; University of Florida Health Cancer Center, Gainesville, Florida.

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2022 Feb 15; Vol. 28 (4), pp. 756-769.