Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Portia S. Lombardo"'
Autor:
William B. Kinlaw, William B. Coleman, Burton L. Eisenberg, Catherine J. Fricano, Leila Chaychi, Luika A. Timmerman, Johannes V. Swinnen, Peter M. Morganelli, Vincent A. Memoli, Heather M. Froehlich, Jason R. Pettus, Wendy A. Wells, Brea C. Lipe, Alison J. Flanagan, Portia S. Lombardo, Evelien Rysman, Nancy B. Kuemmerle
Supplementary Figures 1-3, Table 1 from Lipoprotein Lipase Links Dietary Fat to Solid Tumor Cell Proliferation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6929d33ad0a836799c3868e6b04bde6e
https://doi.org/10.1158/1535-7163.22496952.v1
https://doi.org/10.1158/1535-7163.22496952.v1
Autor:
William B. Kinlaw, William B. Coleman, Burton L. Eisenberg, Catherine J. Fricano, Leila Chaychi, Luika A. Timmerman, Johannes V. Swinnen, Peter M. Morganelli, Vincent A. Memoli, Heather M. Froehlich, Jason R. Pettus, Wendy A. Wells, Brea C. Lipe, Alison J. Flanagan, Portia S. Lombardo, Evelien Rysman, Nancy B. Kuemmerle
Many types of cancer cells require a supply of fatty acids (FA) for growth and survival, and interrupting de novo FA synthesis in model systems causes potent anticancer effects. We hypothesized that, in addition to synthesis, cancer cells may obtain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9693758c3b02e567cbc18d60a872ff17
https://doi.org/10.1158/1535-7163.c.6535440
https://doi.org/10.1158/1535-7163.c.6535440
Autor:
Reuben J. Shaw, Sathesh Bhat, Seth J. Parker, H. James Harwood, Jeremy R. Greenwood, Portia S. Lombardo, Sonja N. Brun, Robert U. Svensson, Matthew J. Kolar, Christian M. Metallo, William F. Westlin, Amanda Hutchins, Jeanine L. Van Nostrand, Martina Wallace, Rosana Kapeller, Lillian J. Eichner, Alan Saghatelian, Laurie Gerken, Lilliana Vera, Geraldine Harriman
Publikováno v:
Nature medicine, vol 22, iss 10
Continuous de novo fatty acid synthesis is a common feature of cancer that is required to meet the biosynthetic demands of a growing tumor. This process is controlled by the rate-limiting enzyme acetyl-CoA carboxylase (ACC), an attractive but traditi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f0d60dab900558853c35c1c76c67eb3
https://pubmed.ncbi.nlm.nih.gov/27807350
https://pubmed.ncbi.nlm.nih.gov/27807350
Autor:
Luika A. Timmerman, William B. Coleman, Jason R. Pettus, Vincent A. Memoli, Heather M. Froehlich, Johannes V. Swinnen, Peter M. Morganelli, Nancy B. Kuemmerle, Wendy A. Wells, William B. Kinlaw, Alison J. Flanagan, Leila Chaychi, Burton L. Eisenberg, Brea Lipe, Portia S. Lombardo, Catherine J. Fricano, Evelien Rysman
Publikováno v:
Molecular Cancer Therapeutics. 10:427-436
Many types of cancer cells require a supply of fatty acids (FA) for growth and survival, and interrupting de novo FA synthesis in model systems causes potent anticancer effects. We hypothesized that, in addition to synthesis, cancer cells may obtain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64b4defa67bfa73e97f6311ee76991ec
https://doi.org/10.1158/1535-7163.mct-10-0802
https://doi.org/10.1158/1535-7163.mct-10-0802
Autor:
Peter M. Morganelli, Portia S. Lombardo, Burton L. Eisenberg, William B. Kinlaw, Johannes V. Swinnen, Arne M Olsen, Nancy B. Kuemmerle, Alison J. Flanagan
Publikováno v:
International Journal of Oncology. 36
Liposarcomas (LS) are mesenchymal tumors that can recur after surgical resection and often do not respond to presently available medical therapies. This study demonstrates the dependence of LS on de novo long-chain fatty acid synthesis for growth. Li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8111d45f73e433e3589b859ee35540ea
https://doi.org/10.3892/ijo_00000616
https://doi.org/10.3892/ijo_00000616