Circuit-based interventions in the dentate gyrus rescue epilepsy-associated cognitive dysfunction.

Autor: Kahn JB; Department of Neuroscience, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Port RG; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.; The Research Institute of the Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA., Yue C; The Research Institute of the Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA., Takano H; The Research Institute of the Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Coulter DA; Department of Neuroscience, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.; The Research Institute of the Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

Publikováno v: Brain : a journal of neurology [Brain] 2019 Sep 01; Vol. 142 (9), pp. 2705-2721.

Children with Autism Spectrum Disorder Demonstrate Regionally Specific Altered Resting-State Phase-Amplitude Coupling.

Autor: Port RG; 1 Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.; 2 Department of Radiology, Lurie Family Foundations MEG Imaging Center, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Dipiero MA; 2 Department of Radiology, Lurie Family Foundations MEG Imaging Center, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Ku M; 2 Department of Radiology, Lurie Family Foundations MEG Imaging Center, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Liu S; 2 Department of Radiology, Lurie Family Foundations MEG Imaging Center, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Blaskey L; 2 Department of Radiology, Lurie Family Foundations MEG Imaging Center, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.; 3 Department of Pediatrics, Center for Autism Research, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Kuschner ES; 1 Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.; 2 Department of Radiology, Lurie Family Foundations MEG Imaging Center, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Edgar JC; 2 Department of Radiology, Lurie Family Foundations MEG Imaging Center, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.; 4 Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Roberts TPL; 2 Department of Radiology, Lurie Family Foundations MEG Imaging Center, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.; 4 Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Berman JI; 2 Department of Radiology, Lurie Family Foundations MEG Imaging Center, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.; 4 Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

Publikováno v: Brain connectivity [Brain Connect] 2019 Jun; Vol. 9 (5), pp. 425-436. Date of Electronic Publication: 2019 Apr 24.

Protocadherin 10 alters γ oscillations, amino acid levels, and their coupling; baclofen partially restores these oscillatory deficits.

Autor: Port RG; Department of Psychiatry, University of Pennsylvania Perelman, School of Medicine, Philadelphia, PA 19104, USA; Lurie Family Foundations MEG Imaging Center, Department of Radiology, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA., Gajewski C; Department of Psychiatry, University of Pennsylvania Perelman, School of Medicine, Philadelphia, PA 19104, USA., Krizman E; Children's Hospital of Philadelphia Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Pediatric, University of Pennsylvania, Philadelphia, PA 19104, USA., Dow HC; Department of Psychiatry, University of Pennsylvania Perelman, School of Medicine, Philadelphia, PA 19104, USA., Hirano S; Department of Cell Biology, Kansai Medical University, 2-5-1 Shinmachi, Hirakata, Osaka 573-1010, Japan., Brodkin ES; Department of Psychiatry, University of Pennsylvania Perelman, School of Medicine, Philadelphia, PA 19104, USA., Carlson GC; Department of Psychiatry, University of Pennsylvania Perelman, School of Medicine, Philadelphia, PA 19104, USA., Robinson MB; Children's Hospital of Philadelphia Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Pediatric, University of Pennsylvania, Philadelphia, PA 19104, USA; Systems Pharmacology and Experimental Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, USA., Roberts TPL; Lurie Family Foundations MEG Imaging Center, Department of Radiology, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA., Siegel SJ; Department of Psychiatry, University of Pennsylvania Perelman, School of Medicine, Philadelphia, PA 19104, USA. Electronic address: Steven.Siegel@med.usc.edu.

Publikováno v: Neurobiology of disease [Neurobiol Dis] 2017 Dec; Vol. 108, pp. 324-338. Date of Electronic Publication: 2017 Aug 24.

Sociability Deficits and Altered Amygdala Circuits in Mice Lacking Pcdh10, an Autism Associated Gene.

Autor: Schoch H; Cell and Molecular Biology Graduate Group, Perelman School of Medicine at the University of Pennsylvania, Philadelphia., Kreibich AS; Center for Neurobiology and Behavior, Perelman School of Medicine at the University of Pennsylvania, Philadelphia., Ferri SL; Department of Biology, University of Pennsylvania, Philadelphia., White RS; Center for Neurobiology and Behavior, Perelman School of Medicine at the University of Pennsylvania, Philadelphia., Bohorquez D; Center for Neurobiology and Behavior, Perelman School of Medicine at the University of Pennsylvania, Philadelphia., Banerjee A; Center for Neurobiology and Behavior, Perelman School of Medicine at the University of Pennsylvania, Philadelphia., Port RG; Center for Neurobiology and Behavior, Perelman School of Medicine at the University of Pennsylvania, Philadelphia., Dow HC; Center for Neurobiology and Behavior, Perelman School of Medicine at the University of Pennsylvania, Philadelphia., Cordero L; Center for Neurobiology and Behavior, Perelman School of Medicine at the University of Pennsylvania, Philadelphia., Pallathra AA; Center for Neurobiology and Behavior, Perelman School of Medicine at the University of Pennsylvania, Philadelphia., Kim H; Center for Neurobiology and Behavior, Perelman School of Medicine at the University of Pennsylvania, Philadelphia., Li H; Department of Biostatistics and Epidemiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia., Bilker WB; Department of Biostatistics and Epidemiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia., Hirano S; Department of Cell Biology, Kansai Medical University, Osaka, Japan., Schultz RT; Department of Psychiatry,Perelman School of Medicine at the University of Pennsylvania, Philadelphia; Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia; Center for Autism Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Borgmann-Winter K; Center for Neurobiology and Behavior, Perelman School of Medicine at the University of Pennsylvania, Philadelphia; Department of Child and Adolescent Psychiatry, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Hahn CG; Center for Neurobiology and Behavior, Perelman School of Medicine at the University of Pennsylvania, Philadelphia., Feldmeyer D; Institute of Neuroscience and Medicine, Forschungzentrum Julich, Julich; Department of Psychiatry, Psychotherapy and Psychosomatics, Medical School, RWTH Aachen University, Aachen, Germany., Carlson GC; Center for Neurobiology and Behavior, Perelman School of Medicine at the University of Pennsylvania, Philadelphia., Abel T; Department of Biology, University of Pennsylvania, Philadelphia., Brodkin ES; Center for Neurobiology and Behavior, Perelman School of Medicine at the University of Pennsylvania, Philadelphia. Electronic address: ebrodkin@mail.med.upenn.edu.

Publikováno v: Biological psychiatry [Biol Psychiatry] 2017 Feb 01; Vol. 81 (3), pp. 193-202. Date of Electronic Publication: 2016 Jun 16.

Auditory encoding abnormalities in children with autism spectrum disorder suggest delayed development of auditory cortex.

Autor: Edgar JC; Lurie Family Foundations MEG Imaging Center, Department of Radiology, Children's Hospital of Philadelphia, 34th and Civic Center Blvd, Wood Building, Suite 2115, Philadelphia, PA 19104 USA., Fisk Iv CL; Lurie Family Foundations MEG Imaging Center, Department of Radiology, Children's Hospital of Philadelphia, 34th and Civic Center Blvd, Wood Building, Suite 2115, Philadelphia, PA 19104 USA., Berman JI; Lurie Family Foundations MEG Imaging Center, Department of Radiology, Children's Hospital of Philadelphia, 34th and Civic Center Blvd, Wood Building, Suite 2115, Philadelphia, PA 19104 USA., Chudnovskaya D; Lurie Family Foundations MEG Imaging Center, Department of Radiology, Children's Hospital of Philadelphia, 34th and Civic Center Blvd, Wood Building, Suite 2115, Philadelphia, PA 19104 USA., Liu S; Lurie Family Foundations MEG Imaging Center, Department of Radiology, Children's Hospital of Philadelphia, 34th and Civic Center Blvd, Wood Building, Suite 2115, Philadelphia, PA 19104 USA., Pandey J; Center for Autism Research, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA USA., Herrington JD; Center for Autism Research, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA USA., Port RG; Lurie Family Foundations MEG Imaging Center, Department of Radiology, Children's Hospital of Philadelphia, 34th and Civic Center Blvd, Wood Building, Suite 2115, Philadelphia, PA 19104 USA., Schultz RT; Center for Autism Research, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA USA., Roberts TP; Lurie Family Foundations MEG Imaging Center, Department of Radiology, Children's Hospital of Philadelphia, 34th and Civic Center Blvd, Wood Building, Suite 2115, Philadelphia, PA 19104 USA.

Publikováno v: Molecular autism [Mol Autism] 2015 Dec 30; Vol. 6, pp. 69. Date of Electronic Publication: 2015 Dec 30 (Print Publication: 2015).