Zobrazeno 1 - 10 of 2 468 pro vyhledávání: '"Porrino LJ"'
1
Akademický článek
Prolonged exposure to cocaine self-administration results in a continued progression of alterations in functional activity in a nonhuman primate model.
Autor: Porrino LJ; Center for the Neurobiology of Addiction Treatment, Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston Salem, NC, USA., Smith HR; Center for the Neurobiology of Addiction Treatment, Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston Salem, NC, USA., Beveridge TJR; Center for the Neurobiology of Addiction Treatment, Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston Salem, NC, USA., Miller MD; Center for the Neurobiology of Addiction Treatment, Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston Salem, NC, USA., Nader SH; Center for the Neurobiology of Addiction Treatment, Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston Salem, NC, USA., Nader MA; Center for the Neurobiology of Addiction Treatment, Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston Salem, NC, USA.
Publikováno v: Drug and alcohol dependence reports [Drug Alcohol Depend Rep] 2023 Mar 18; Vol. 7, pp. 100148. Date of Electronic Publication: 2023 Mar 18 (Print Publication: 2023).
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2
Akademický článek
The Effects of the Dopamine Transporter Ligands JJC8-088 and JJC8-091 on Cocaine versus Food Choice in Rhesus Monkeys.
Autor: Rahimi O; Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston-Salem, North Carolina (O.R., S.R.C., L.J.P., M.A.N.); Medicinal Chemistry Section, Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, Maryland (J.C., J.L., A.H.N.); Department of Neurology, Johns Hopkins Drug Discovery, The Johns Hopkins University School of Medicine, Baltimore, Maryland (J.L., R.R.); and EncepHeal Therapeutics, Inc., Winston-Salem, North Carolina (O.R., S.R.C.)., Cao J; Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston-Salem, North Carolina (O.R., S.R.C., L.J.P., M.A.N.); Medicinal Chemistry Section, Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, Maryland (J.C., J.L., A.H.N.); Department of Neurology, Johns Hopkins Drug Discovery, The Johns Hopkins University School of Medicine, Baltimore, Maryland (J.L., R.R.); and EncepHeal Therapeutics, Inc., Winston-Salem, North Carolina (O.R., S.R.C.)., Lam J; Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston-Salem, North Carolina (O.R., S.R.C., L.J.P., M.A.N.); Medicinal Chemistry Section, Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, Maryland (J.C., J.L., A.H.N.); Department of Neurology, Johns Hopkins Drug Discovery, The Johns Hopkins University School of Medicine, Baltimore, Maryland (J.L., R.R.); and EncepHeal Therapeutics, Inc., Winston-Salem, North Carolina (O.R., S.R.C.)., Childers SR; Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston-Salem, North Carolina (O.R., S.R.C., L.J.P., M.A.N.); Medicinal Chemistry Section, Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, Maryland (J.C., J.L., A.H.N.); Department of Neurology, Johns Hopkins Drug Discovery, The Johns Hopkins University School of Medicine, Baltimore, Maryland (J.L., R.R.); and EncepHeal Therapeutics, Inc., Winston-Salem, North Carolina (O.R., S.R.C.)., Rais R; Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston-Salem, North Carolina (O.R., S.R.C., L.J.P., M.A.N.); Medicinal Chemistry Section, Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, Maryland (J.C., J.L., A.H.N.); Department of Neurology, Johns Hopkins Drug Discovery, The Johns Hopkins University School of Medicine, Baltimore, Maryland (J.L., R.R.); and EncepHeal Therapeutics, Inc., Winston-Salem, North Carolina (O.R., S.R.C.)., Porrino LJ; Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston-Salem, North Carolina (O.R., S.R.C., L.J.P., M.A.N.); Medicinal Chemistry Section, Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, Maryland (J.C., J.L., A.H.N.); Department of Neurology, Johns Hopkins Drug Discovery, The Johns Hopkins University School of Medicine, Baltimore, Maryland (J.L., R.R.); and EncepHeal Therapeutics, Inc., Winston-Salem, North Carolina (O.R., S.R.C.)., Newman AH; Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston-Salem, North Carolina (O.R., S.R.C., L.J.P., M.A.N.); Medicinal Chemistry Section, Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, Maryland (J.C., J.L., A.H.N.); Department of Neurology, Johns Hopkins Drug Discovery, The Johns Hopkins University School of Medicine, Baltimore, Maryland (J.L., R.R.); and EncepHeal Therapeutics, Inc., Winston-Salem, North Carolina (O.R., S.R.C.)., Nader MA; Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston-Salem, North Carolina (O.R., S.R.C., L.J.P., M.A.N.); Medicinal Chemistry Section, Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, Maryland (J.C., J.L., A.H.N.); Department of Neurology, Johns Hopkins Drug Discovery, The Johns Hopkins University School of Medicine, Baltimore, Maryland (J.L., R.R.); and EncepHeal Therapeutics, Inc., Winston-Salem, North Carolina (O.R., S.R.C.) mnader@wakehealth.edu.
Publikováno v: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2023 Mar; Vol. 384 (3), pp. 372-381. Date of Electronic Publication: 2022 Dec 06.
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3
Akademický článek
Residual deficits in functional brain activity after chronic cocaine self-administration in rhesus monkeys.
Autor: Porrino LJ; Department of Physiology and Pharmacology, Wake Forest School of Medicine, Winston Salem, NC, USA. lporrino@wakehealth.edu., Smith HR; Department of Physiology and Pharmacology, Wake Forest School of Medicine, Winston Salem, NC, USA., Beveridge TJR; Department of Physiology and Pharmacology, Wake Forest School of Medicine, Winston Salem, NC, USA., Miller MD; Department of Physiology and Pharmacology, Wake Forest School of Medicine, Winston Salem, NC, USA., Nader SH; Department of Physiology and Pharmacology, Wake Forest School of Medicine, Winston Salem, NC, USA., Nader MA; Department of Physiology and Pharmacology, Wake Forest School of Medicine, Winston Salem, NC, USA.
Publikováno v: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology [Neuropsychopharmacology] 2023 Jan; Vol. 48 (2), pp. 290-298. Date of Electronic Publication: 2021 Aug 12.
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4
Akademický článek
The thalamus encodes and updates context representations during hierarchical cognitive control.
Autor: Chen, Xitong1,2,3 (AUTHOR) xitong-chen@uiowa.edu, Leach, Stephanie C.1,2,3 (AUTHOR), Hollis, Juniper1,2,3 (AUTHOR), Cellier, Dillan1,2,3 (AUTHOR), Hwang, Kai1,2,3 (AUTHOR)
Publikováno v: PLoS Biology. 12/2/2024, Vol. 22 Issue 12, p1-28. 28p.
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5
Akademický článek
Chronic phenmetrazine treatment promotes D 2 dopaminergic and α2-adrenergic receptor desensitization and alters phosphorylation of signaling proteins and local cerebral glucose metabolism in the rat brain.
Autor: Keegan BM; Center for the Neurobiology of Addiction Treatment, Department of Physiology and Pharmacology, Wake Forest School of Medicine, Medical Center Blvd., Winston-Salem, NC 27157, USA., Dreitzler AL; Center for the Neurobiology of Addiction Treatment, Department of Physiology and Pharmacology, Wake Forest School of Medicine, Medical Center Blvd., Winston-Salem, NC 27157, USA., Sexton T; Center for the Neurobiology of Addiction Treatment, Department of Physiology and Pharmacology, Wake Forest School of Medicine, Medical Center Blvd., Winston-Salem, NC 27157, USA., Beveridge TJR; Center for the Neurobiology of Addiction Treatment, Department of Physiology and Pharmacology, Wake Forest School of Medicine, Medical Center Blvd., Winston-Salem, NC 27157, USA., Smith HR; Center for the Neurobiology of Addiction Treatment, Department of Physiology and Pharmacology, Wake Forest School of Medicine, Medical Center Blvd., Winston-Salem, NC 27157, USA., Miller MD; Center for the Neurobiology of Addiction Treatment, Department of Physiology and Pharmacology, Wake Forest School of Medicine, Medical Center Blvd., Winston-Salem, NC 27157, USA., Blough BE; Center for Drug Discovery, RTI International, Research Triangle Park, NC 27709, USA., Porrino LJ; Center for the Neurobiology of Addiction Treatment, Department of Physiology and Pharmacology, Wake Forest School of Medicine, Medical Center Blvd., Winston-Salem, NC 27157, USA., Childers SR; Center for the Neurobiology of Addiction Treatment, Department of Physiology and Pharmacology, Wake Forest School of Medicine, Medical Center Blvd., Winston-Salem, NC 27157, USA., Howlett AC; Center for the Neurobiology of Addiction Treatment, Department of Physiology and Pharmacology, Wake Forest School of Medicine, Medical Center Blvd., Winston-Salem, NC 27157, USA. Electronic address: ahowlett@wakehealth.edu.
Publikováno v: Brain research [Brain Res] 2021 Feb 23; Vol. 1761, pp. 147387. Date of Electronic Publication: 2021 Feb 23.
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6
Akademický článek
Functional brain activity is globally elevated by dopamine D2 receptor knockdown in the ventral tegmental area.
Autor: Martin TA; Department of Physiology and Pharmacology, Wake Forest School of Medicine, Winston-Salem, NC 27157, United States., Smith HR; Department of Physiology and Pharmacology, Wake Forest School of Medicine, Winston-Salem, NC 27157, United States., Luessen DJ; Department of Physiology and Pharmacology, Wake Forest School of Medicine, Winston-Salem, NC 27157, United States., Chen R; Department of Physiology and Pharmacology, Wake Forest School of Medicine, Winston-Salem, NC 27157, United States., Porrino LJ; Department of Physiology and Pharmacology, Wake Forest School of Medicine, Winston-Salem, NC 27157, United States. Electronic address: lporrino@wakehealth.edu.
Publikováno v: Brain research [Brain Res] 2020 Jan 15; Vol. 1727, pp. 146552. Date of Electronic Publication: 2019 Nov 11.
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7
Akademický článek
Retinoic acid-mediated homeostatic plasticity in the nucleus accumbens core contributes to incubation of cocaine craving.
Autor: Wunsch AM; Department of Behavioral Neuroscience, Oregon Health & Science University, Portland, OR, 97212, USA.; Department of Neuroscience, Rosalind Franklin University of Medicine and Science, North Chicago, IL, 60064, USA., Hwang EK; Department of Behavioral Neuroscience, Oregon Health & Science University, Portland, OR, 97212, USA., Funke JR; Department of Behavioral Neuroscience, Oregon Health & Science University, Portland, OR, 97212, USA.; Department of Neuroscience, Rosalind Franklin University of Medicine and Science, North Chicago, IL, 60064, USA.; Graduate School of Biomedical Sciences, Tufts University, Boston, MA, 02111, USA., Baker R; Department of Behavioral Neuroscience, Oregon Health & Science University, Portland, OR, 97212, USA.; College of Education, Health, and Human Sciences, Florida State University, Tallahassee, FL, 32306, USA., Moutier A; Department of Behavioral Neuroscience, Oregon Health & Science University, Portland, OR, 97212, USA.; Yecuris Corporation, Tualatin, OR, 97062, USA., Milovanovic M; Department of Neuroscience, Rosalind Franklin University of Medicine and Science, North Chicago, IL, 60064, USA., Green TA; Department of Pharmacology & Toxicology, University of Texas Medical Branch, Galveston, TX, 77555, USA., Wolf ME; Department of Behavioral Neuroscience, Oregon Health & Science University, Portland, OR, 97212, USA. wolfmar@ohsu.edu.; Department of Neuroscience, Rosalind Franklin University of Medicine and Science, North Chicago, IL, 60064, USA. wolfmar@ohsu.edu.
Publikováno v: Psychopharmacology [Psychopharmacology (Berl)] 2024 Oct; Vol. 241 (10), pp. 1983-2001. Date of Electronic Publication: 2024 Jun 27.
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8
Akademický článek
Regional elevations in microglial activation and cerebral glucose utilization in frontal white matter tracts of rhesus monkeys following prolonged cocaine self-administration.
Autor: Smith HR; Department of Physiology and Pharmacology, Wake Forest School of Medicine, Center for the Neurobiology of Addiction Treatment, One Medical Center Boulevard, Winston-Salem, NC, 27157-1083, USA., Beveridge TJR; Department of Physiology and Pharmacology, Wake Forest School of Medicine, Center for the Neurobiology of Addiction Treatment, One Medical Center Boulevard, Winston-Salem, NC, 27157-1083, USA.; Medical Affairs-Oncology, Ipsen Biopharmaceuticals Inc., 106 Allen Road, Basking Ridge, NJ, 07920, USA., Nader SH; Department of Physiology and Pharmacology, Wake Forest School of Medicine, Center for the Neurobiology of Addiction Treatment, One Medical Center Boulevard, Winston-Salem, NC, 27157-1083, USA., Nader MA; Department of Physiology and Pharmacology, Wake Forest School of Medicine, Center for the Neurobiology of Addiction Treatment, One Medical Center Boulevard, Winston-Salem, NC, 27157-1083, USA., Porrino LJ; Department of Physiology and Pharmacology, Wake Forest School of Medicine, Center for the Neurobiology of Addiction Treatment, One Medical Center Boulevard, Winston-Salem, NC, 27157-1083, USA. lporrino@wakehealth.edu.
Publikováno v: Brain structure & function [Brain Struct Funct] 2019 May; Vol. 224 (4), pp. 1417-1428. Date of Electronic Publication: 2019 Feb 12.
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9
Akademický článek
Brain activity associated with social exclusion overlaps with drug-related frontal-striatal circuitry in cocaine users: A pilot study.
Autor: Hanlon CA; Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston-Salem, NC, 27157, USA.; Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, 29425, USA., Shannon EE; Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston-Salem, NC, 27157, USA., Porrino LJ; Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston-Salem, NC, 27157, USA.
Publikováno v: Neurobiology of stress [Neurobiol Stress] 2018 Oct 30; Vol. 10, pp. 100137. Date of Electronic Publication: 2018 Oct 30 (Print Publication: 2019).
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