Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Porntipa Korprasertthaworn"'
Publikováno v:
Toxicology Reports, Vol 9, Iss , Pp 1846-1852 (2022)
Herbal products are widely used in cancer patients via co−administration with chemotherapy. Previous studies have demonstrated that pharmacokinetic interactions between herbs and anticancer drugs exist due to inhibition of drug−metabolizing enzym
Externí odkaz:
https://doaj.org/article/fac47667ba22412b90045a110713435e
Autor:
Titus Mohan, Michael D. Wiese, Porntipa Korprasertthaworn, Geoffrey T. Tucker, Andrew Rowland, Thomas M. Polasek, Michael J. Sorich, Amin Rostami-Hodjegan, Vidya Perera
Publikováno v:
British Journal of Clinical Pharmacology
Aim: The aim of the present study was to predict olanzapine (OLZ) exposure in individual patients using physiologically based pharmacokinetic modelling and simulation (PBPK M & S). Methods: A 'bottom-up' PBPK model for OLZ was constructed in Simcyp®
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d900b2c796dd2b1c641ac76fe5a24f39
https://doi.org/10.1111/bcp.13480
https://doi.org/10.1111/bcp.13480
Publikováno v:
Pharmacogenetics and Genomics. 26:453-461
To extend our understanding of how interindividual variability mediates the efficacy of cancer treatment.The kinetics of dacarbazine (DTIC) N-demethylation by the most frequent polymorphic variants of CYP1A1 (T461N, I462V) and CYP1A2 (F186L, D348N, I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f54e1b1de8e49bbe9322ac405309df70
https://doi.org/10.1097/fpc.0000000000000236
https://doi.org/10.1097/fpc.0000000000000236
Autor:
Benjamin C. Lewis, Porntipa Korprasertthaworn, Peter I. Mackenzie, Andrew Rowland, Krongtong Yoovathaworn, John O. Miners
Publikováno v:
Biochemical Pharmacology. 84:1511-1521
This article appeared in a journal published by Elsevier Ltd. Under Elsevier's copyright, mandated authors are not permitted to make work available in an institutional repository.
UGT1A9 contributes to the glucuronidation of numerous drugs and x
UGT1A9 contributes to the glucuronidation of numerous drugs and x
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b41054e2e78bc7b279bfb0723c6006fc
https://doi.org/10.1016/j.bcp.2012.08.026
https://doi.org/10.1016/j.bcp.2012.08.026
Publikováno v:
Drug Metabolism and Pharmacokinetics. 24:482-485
Summary: The human UDP-glucuronosyltransferase, UGT1A9, catalyzes glucuronidation of various endobiotics and xenobiotics. In this study, we sequenced the promoter and exon 1 regions of the UGT1A9 gene in 93 Thai individuals and identified 7 genetic p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::261d16e88b0a88019b968c5c7fdaf952
https://doi.org/10.2133/dmpk.24.482
https://doi.org/10.2133/dmpk.24.482
Autor:
Peter I. Mackenzie, Nuy Chau, John O. Miners, Kushari Burns, Porntipa Korprasertthaworn, Andrew Rowland, Kathleen M. Knights
Publikováno v:
Drug Metabolism and Pharmacokinetics. 32:S53
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32a6553b4340fc250c0bdf2eb6cd83fc
https://doi.org/10.1016/j.dmpk.2016.10.220
https://doi.org/10.1016/j.dmpk.2016.10.220