Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Porntip Supavilai"'
Publikováno v:
Trends in Sciences. 19:4587
Alzheimer’s disease (AD) is a major public health problem worldwide due to an increase in the elderly population. The current pharmacotherapy for the early stages of AD is mainly dependent on cholinesterase inhibitors. Two of the most commonly used
Autor:
Darawan Pinthong, Porntip Supavilai, Sittichai Sillapapongwarakorn, Somchai Yanarojana, Jiraporn Ungwitayatorn, Amnuay Thithapandha
Publikováno v:
Bioinformation
Triterpenoids isolated from Ganoderma lucidum (GLTs) exhibit a broad spectrum of anti-cancer properties, including anti-proliferative, anti-metastatic and anti-angiogenic activities. Current research studies revealed the role by GLTs in inducing apop
Autor:
Kant Sangpairoj, Christopher Power, Pannaree Piromkraipak, Supeenun Unchern, Pornpun Vivithanaporn, Porntip Supavilai, Wuttipong Tirakotai, Kulathida Chaithirayanon
Publikováno v:
Cellular and Molecular Neurobiology. 38:559-573
Glioblastoma is one of the most malignant and aggressive types of brain tumors. 5-lipoxygenase and cysteinyl leukotriene receptor 1 (CysLT1) play a role in human carcinogenesis. Leukotriene receptor antagonists (LTRAs), anti-asthmatic drugs with mild
Autor:
Supeenun Unchern, Natsalil Pongthanaracht, Amnuay Thithapandha, Prasert Assantachai, Porntip Supavilai, Darawan Pinthong, Somchai Yanarojana
Publikováno v:
Clinical Interventions in Aging
Natsalil Pongthanaracht,1 Somchai Yanarojana,1 Darawan Pinthong,1 Supeenun Unchern,1 Amnuay Thithapandha,1 Prasert Assantachai,2 Porntip Supavilai11Department of Pharmacology, Faculty of Science, 2Department of Preventive and Social Medicine, Faculty
Autor:
Pannaree, Piromkraipak, Kant, Sangpairoj, Wuttipong, Tirakotai, Kulathida, Chaithirayanon, Supeenun, Unchern, Porntip, Supavilai, Christopher, Power, Pornpun, Vivithanaporn
Publikováno v:
Cellular and molecular neurobiology. 38(2)
Glioblastoma is one of the most malignant and aggressive types of brain tumors. 5-lipoxygenase and cysteinyl leukotriene receptor 1 (CysLT1) play a role in human carcinogenesis. Leukotriene receptor antagonists (LTRAs), anti-asthmatic drugs with mild
Autor:
N. Trachu, Ekawat Pasomsub, Darawan Pinthong, Insee Sensorn, Ekaphop Sirachainan, Chonlaphat Sukasem, Porntip Supavilai, Montri Chamnanphon, Sansanee Wongwaisayawan
Publikováno v:
OncoTargets and therapy
Insee Sensorn,1,* Chonlaphat Sukasem,2,* Ekaphop Sirachainan,3 Montri Chamnanphon,2 Ekawat Pasomsub,4 Narumol Trachu,5 Porntip Supavilai,1 Darawan Pinthong,1 Sansanee Wongwaisayawan6 1Department of Pharmacology, Faculty of Science, Mahidol University
Autor:
Anusorn Thampithak, Pawinee Piyachaturawat, Benjawan Meesarapee, Porntip Supavilai, Yupin Sanvarinda, Yamaratee Jaisin, Piyarat Govitrapong, Sukumal Chongthammakun
Publikováno v:
Neuroscience Letters. 462:171-175
Overproduction of pro-inflammatory mediators resulting from chronic activation of microglia has been implicated in many neurodegenerative disorders, such as Parkinson's disease and Alzheimer's disease. In this study, we investigated the effects of (3
Autor:
Porntip Supavilai, Chonlaphat Sukasem, Insee Sensorn, N. Trachu, Ekawat Pasomsub, Ekaphop Sirachainan, Darawan Pinthong, Montri Chamnanphon
Publikováno v:
Pharmacogenomics and Personalized Medicine
Insee Sensorn,1 Ekaphop Sirachainan,2 Montri Chamnanphon,3 Ekawat Pasomsub,4 Narumol Trachu,5 Porntip Supavilai,1 Chonlaphat Sukasem,3 Darawan Pinthong11Department of Pharmacology, Faculty of Science, Mahidol University, Bangkok, Thailand; 2Division
Autor:
Hendrikus Boddeke, JoséM. Palacios, Karl-Heinz Wiederhold, Esteban Pombo-Villar, Guadalupe Mengod, Porntip Supavilai
Publikováno v:
European journal of pharmacology-Molecular pharmacology section, 226(4), 317-325
The preparation and the biological activities of the four stereoisomers of 3-[5-(3-amino-1,2,4-oxadiazol)yl]-1-azabicyclo [2.2.1]heptane are described. The most potent stereoisomer, 3a, has the 3R, 4R configuration, and in vitro activities in (pD 2 (
Publikováno v:
Bioorganic and Medicinal Chemistry Letters, 2(5), 501-504. American Chemical Society
(IR,4R,6R)-(−)-6-Carbomethoxy-2-azabicyclo[2.2.1]heptane 8a, (1R,4R,6R)-(−)-6-carbomethoxy-2-methyl-2-zabicyclo[2.2.1]heptane 2a and their enantiomers 8b and 2b have been prepared as rigid analogues of the enantiomorphic conformations of arecolin