Chitooligomer-Immobilized Biointerfaces with Micropatterned Geometries for Unidirectional Alignment of Myoblast Cells

Autor: Pornthida Poosala, Takuya Kitaoka

Publikováno v: Biomolecules, Vol 6, Iss 1, p 12 (2016)

Skeletal muscle possesses a robust capacity to regenerate functional architectures with a unidirectional orientation. In this study, we successfully arranged skeletal myoblast (C2C12) cells along micropatterned gold strips on which chitohexaose was d

Externí odkaz: https://doaj.org/article/c66a00b358ec4bb094dfb5fa0672e416

Abstract 235: A Micropeptide Regulator of Voltage-gated Potassium Channels Controls Cardiac Rhythm

Autor: Pornthida Poosala, Douglas M Anderson, Sean Lindley, Xiaorong Xu Parks, Kelly M Anderson, Coeli M. Lopes

Publikováno v: Circulation Research. 125

Voltage-gated potassium (K + ) channels (VGKCs) are essential regulators of the cardiac action potential and are required to maintain normal heart rhythm and contractility. Voltage-dependent activation, conductance and membrane trafficking of K + cha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4c30384e0c9b9a1a357757bcfbda5623
https://doi.org/10.1161/res.125.suppl_1.235

Spatial Geometries of Self-Assembled Chitohexaose Monolayers Regulate Myoblast Fusion

Autor: Hirofumi Ichinose, Takuya Kitaoka, Pornthida Poosala

Publikováno v: International Journal of Molecular Sciences, Vol 17, Iss 5, p 686 (2016)
International Journal of Molecular Sciences; Volume 17; Issue 5; Pages: 686
International Journal of Molecular Sciences

Myoblast fusion into functionally-distinct myotubes to form in vitro skeletal muscle constructs under differentiation serum-free conditions still remains a challenge. Herein, we report that our microtopographical carbohydrate substrates composed of b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c9cc8f5fbe78bda7a9c6dc0ad1118c6
http://www.mdpi.com/1422-0067/17/5/686