Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Pornthep Sompornpisut"'
Autor:
Ashok R. Nayak, Warin Rangubpit, Alex H. Will, Yifan Hu, Pablo Castro-Hartmann, Joshua J. Lobo, Kelly Dryden, Graham D. Lamb, Pornthep Sompornpisut, Montserrat Samsó
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract RyR1 is an intracellular Ca2+ channel important in excitable cells such as neurons and muscle fibers. Ca2+ activates it at low concentrations and inhibits it at high concentrations. Mg2+ is the main physiological RyR1 inhibitor, an effect th
Externí odkaz:
https://doaj.org/article/84e456c577cc459aa27a8ef47bfa4340
Publikováno v:
AIMS Biophysics, Vol 9, Iss 4, Pp 330-340 (2022)
Thermal response of an envelope protein conformation from coronavirus-2 (CoVE) is studied by a coarse-grained Monte Carlo simulation. Three distinct segments, the N-terminal, Trans-membrane, and C-terminal are verified from its specific contact profi
Externí odkaz:
https://doaj.org/article/aad1521b5538426ab4e9d0cea14b2d13
Publikováno v:
AIP Advances, Vol 12, Iss 10, Pp 105027-105027-6 (2022)
Large-scale Monte Carlo simulations are performed to investigate local and global thermodynamic properties of the main protease in SARS (MP1) and COVID-19 (MP2) coronaviruses using a bond-fluctuating coarse-grained protein model for a range of temper
Externí odkaz:
https://doaj.org/article/45539f03a5c64f23b9c13bf68c76b8e1
Publikováno v:
AIMS Biophysics, Vol 8, Iss 1, Pp 103-110 (2021)
>Unfolding of a coarse-grained COVN protein from its native configuration shows a linear response with increasing temperature followed by non-monotonic double peaks in its radius of gyration. The protein conforms to a random coil of folded segments i
Externí odkaz:
https://doaj.org/article/a551df0326184b9e9b5d966ab9ddf1ed
Globular bundles and entangled network of proteins (CorA) by a coarse-grained Monte Carlo simulation
Publikováno v:
AIMS Biophysics, Vol 6, Iss 2, Pp 68-82 (2019)
Using a coarse-grained model, self-organized assembly of proteins (e.g., CorA and its inner segment iCorA) is studied by examining quantities such as contact profile, radius of gyration, and structure factor as a function of protein concentration at
Externí odkaz:
https://doaj.org/article/0776cf4c202745aba3d6a5555042b5f8
Autor:
Rudramani Pokhrel, Pornthep Sompornpisut, Prem Chapagain, Brian Olson, Bernard Gerstman, R. B. Pandey
Publikováno v:
AIP Advances, Vol 8, Iss 12, Pp 125129-125129-8 (2018)
The VP40 protein plays a critical role in coordinating the virion assembly, budding, and replication of the Ebola virus. Efforts have been made in recent years to understand various aspects of VP40 structure, dynamics, and function such as assembly o
Externí odkaz:
https://doaj.org/article/6fd57b7fff6f448f9259e5573ee67043
Publikováno v:
The Scientific World Journal, Vol 2013 (2013)
Dicoumarols and coumarin derivatives have shown a variety of pharmaceutical activities and have been found to be potent inhibitor for the NAD(P)H-dependent flavoproteins. In this report, dicoumarol and its derivatives containing the substituted benze
Externí odkaz:
https://doaj.org/article/91b207d214d04fd2baf97568affc5ade
Autor:
Ras B. Pandey, Pornthep Sompornpisut
Publikováno v:
Jom (Warrendale, Pa. : 1989)
Self-organizing structures of CoVE proteins have been investigated using a coarse-grained model in Monte Carlo simulations as a function of temperature (T) in a range covering the native (low T) to denatured (high T) phases. The presence of even a fe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dae6bcdfb7b27ce6602f6174bd433414
http://europepmc.org/articles/PMC8153093
http://europepmc.org/articles/PMC8153093
Publikováno v:
Science Proceedings Series. 2:34-38
Site-directed spin labeling (SDSL) combined with continuous-wave electron paramagnetic resonance (CW-EPR) spectroscopy has become a useful approach to investigate the structural and dynamical properties of biomolecules, especially membrane protein. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39980f02f936d9d9dab2105d3b0b156f
https://doi.org/10.31580/sps.v2i1.1239
https://doi.org/10.31580/sps.v2i1.1239