Zobrazeno 1 - 10 of 79 pro vyhledávání: '"Pornpimol, Rongnoparut"'
1
Akademický článek
Inhibition of human cytochromes P450 2A6 and 2A13 by flavonoids, acetylenic thiophenes and sesquiterpene lactones from Pluchea indica and Vernonia cinerea
Autor: Supattra Boonruang, Khanistha Prakobsri, Phisit Pouyfung, Ekaruth Srisook, Aruna Prasopthum, Pornpimol Rongnoparut, Songklod Sarapusit
Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 1136-1142 (2017)
The human liver cytochrome P450 (CYP) 2A6 and the respiratory CYP2A13 enzymes play role in nicotine metabolism and activation of tobacco-specific nitrosamine carcinogens. Inhibition of both enzymes could offer a strategy for smoking abstinence and de
Externí odkaz: https://doaj.org/article/75f09d2a437d4acba2d87cedfbba1e00
Zobrazit plný text záznamu
2
Structure–activity relationship and in vitro inhibition of human cytochrome CYP2A6 and CYP2A13 by flavonoids
Autor: Khanistha Prakobsri, Aruna Prasopthum, Phisit Pouyfung, Supattra Boonruang, Songklod Sarapusit, Pornpimol Rongnoparut
Publikováno v: Xenobiotica. 50:630-639
Cigarette smoking is one of the major risk factors of various diseases including respiratory diseases and lung cancer. While the liver-specific CYP2A6 is associated with the nicotine clearance and ...
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ed73a7e3afd5ab685d2bad2544725e2c
https://doi.org/10.1080/00498254.2019.1675101
Zobrazit plný text záznamu
3
Anti-proliferative effect of 8α-tigloyloxyhirsutinolide-13-O-acetate (8αTGH) isolated from Vernonia cinerea on oral squamous cell carcinoma through inhibition of STAT3 and STAT2 phosphorylation
Autor: Ariyaphong Wongnoppavich, Pornpimol Rongnoparut, Sirinthip Choonate, Phisit Pouyfung, Kongthawat Chairatvit
Publikováno v: Phytomedicine. 52:238-246
Background The high mortality rate of oral cancers has stimulated the search for effective herbal medicines and their pharmacological targets. Vernonia cinerea, a perennial tropical herb, is wildly used as a traditional folk medicine for treatment of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8498ddb0656efbd1e0f93afa1e0e475
https://doi.org/10.1016/j.phymed.2018.09.211
Zobrazit plný text záznamu
4
Akademický článek
Distal effect of amino acid substitutions in CYP2C9 polymorphic variants causes differences in interatomic interactions against (S)-warfarin.
Autor: Panida Lertkiatmongkol, Anunchai Assawamakin, George White, Gaurav Chopra, Pornpimol Rongnoparut, Ram Samudrala, Sissades Tongsima
Publikováno v: PLoS ONE, Vol 8, Iss 9, p e74053 (2013)
Cytochrome P450 2C9 (CYP2C9) is crucial in excretion of commonly prescribed drugs. However, changes in metabolic activity caused by CYP2C9 polymorphisms inevitably result in adverse drug effects. CYP2C9*2 and *3 are prevalent in Caucasian populations
Externí odkaz: https://doaj.org/article/b583c5c17ecb45ccb1f8645a180f99eb
Zobrazit plný text záznamu
6
Effects of Vernonia cinerea Compounds on Drug-metabolizing Cytochrome P450s in Human Liver Microsomes
Autor: Songklod Sarapusit, Pornpimol Rongnoparut, Phisit Pouyfung
Publikováno v: Phytotherapy Research. 31:1916-1925
Vernonia cinerea has been widely used in traditional medicines for various diseases and shown to aid in smoking abstinence and has anticancer properties. V. cinerea bioactive compounds, including flavonoids and hirsutinolide-type sesquiterpene lacton
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d83c23387e1265848cf359dc315e3d37
https://doi.org/10.1002/ptr.5939
Zobrazit plný text záznamu
7
Inhibition of human cytochromes P450 2A6 and 2A13 by flavonoids, acetylenic thiophenes and sesquiterpene lactones from Pluchea indica and Vernonia cinerea
Autor: Phisit Pouyfung, Khanistha Prakobsri, Supattra Boonruang, Ekaruth Srisook, Aruna Prasopthum, Songklod Sarapusit, Pornpimol Rongnoparut
Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 1136-1142 (2017)
Journal of Enzyme Inhibition and Medicinal Chemistry
The human liver cytochrome P450 (CYP) 2A6 and the respiratory CYP2A13 enzymes play role in nicotine metabolism and activation of tobacco-specific nitrosamine carcinogens. Inhibition of both enzymes could offer a strategy for smoking abstinence and de
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbb30893fd6f67dc691ceefa0234c053
https://doaj.org/article/75f09d2a437d4acba2d87cedfbba1e00
Zobrazit plný text záznamu
8
Structure-activity relationship and
Autor: Supattra, Boonruang, Khanistha, Prakobsri, Phisit, Pouyfung, Aruna, Prasopthum, Pornpimol, Rongnoparut, Songklod, Sarapusit
Publikováno v: Xenobiotica; the fate of foreign compounds in biological systems. 50(6)
Cigarette smoking is one of the major risk factors of various diseases including respiratory diseases and lung cancer. While the liver-specific CYP2A6 is associated with the nicotine clearance and smoking addiction, the metabolic activation of the to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4a9408e7b42d5c786743b65a1bc5aa0a
https://pubmed.ncbi.nlm.nih.gov/31578905
Zobrazit plný text záznamu
9
Structural and Functional Studies of the Membrane-Binding Domain of NADPH-Cytochrome P450 Oxidoreductase
Autor: Jung-Ja P. Kim, Panida Duangkaew, Chuanwu Xia, Anna L. Shen, Jimmy B. Feix, Rattanawadee Kotewong, Pornpimol Rongnoparut
Publikováno v: Biochemistry. 58(19)
NADPH-cytochrome P450 oxidoreductase (CYPOR), the essential flavoprotein of the microsomal cytochrome P450 monooxygenase system, is anchored in the phospholipid bilayer by its amino-terminal membrane-binding domain (MBD), which is necessary for effic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e37d1dc7fa2234434a5a64362d58b325
https://pubmed.ncbi.nlm.nih.gov/31009206
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje