Exploring the heterogeneous transcriptional response of the CNS to systemic LPS and Poly(I:C)

Autor: Bormann, Daniel, Copic, Dragan, Klas, Katharina, Direder, Martin, Riedl, Christian J., Testa, Giulia, Kühtreiber, Hannes, Poreba, Emilia, Hametner, Simon, Golabi, Bahar, Salek, Melanie, Haider, Carmen, Endmayr, Verena, Shaw, Lisa E., Höftberger, Romana, Ankersmit, Hendrik J., Mildner, Michael

Publikováno v: In Neurobiology of Disease November 2023 188

Single nucleus RNA sequencing reveals glial cell type-specific responses to ischemic stroke.

Autor: Bormann D; Applied Immunology Laboratory, Department of Thoracic Surgery, Medical University of Vienna, 1090 Vienna, Austria.; Aposcience AG, 1200 Vienna, Austria., Knoflach M; Department of Neurology, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.; VASCage, Research Centre on Vascular Ageing and Stroke, 6020 Innsbruck, Austria., Poreba E; Department of Dermatology, Medical University of Vienna, 1090 Vienna, Austria., Riedl CJ; Division of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna, 1090 Vienna, Austria., Testa G; Division of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna, 1090 Vienna, Austria., Orset C; Normandie University, UNICAEN, ESR3P, INSERM UMR-S U1237, Physiopathology and Imaging of Neurological Disorders (PhIND), GIP Cyceron, Institut Blood and Brain @ Caen-Normandie (BB@C), Caen, France.; Department of Clinical Research, Caen-Normandie University Hospital, Caen, France., Levilly A; Normandie University, UNICAEN, ESR3P, INSERM UMR-S U1237, Physiopathology and Imaging of Neurological Disorders (PhIND), GIP Cyceron, Institut Blood and Brain @ Caen-Normandie (BB@C), Caen, France.; Department of Clinical Research, Caen-Normandie University Hospital, Caen, France., Cottereau A; Normandie University, UNICAEN, ESR3P, INSERM UMR-S U1237, Physiopathology and Imaging of Neurological Disorders (PhIND), GIP Cyceron, Institut Blood and Brain @ Caen-Normandie (BB@C), Caen, France.; Department of Clinical Research, Caen-Normandie University Hospital, Caen, France., Jauk P; Division of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna, 1090 Vienna, Austria.; Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, 1090 Vienna, Austria., Hametner S; Division of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna, 1090 Vienna, Austria., Golabi B; Department of Dermatology, Medical University of Vienna, 1090 Vienna, Austria., Copic D; Applied Immunology Laboratory, Department of Thoracic Surgery, Medical University of Vienna, 1090 Vienna, Austria.; Aposcience AG, 1200 Vienna, Austria.; Division of Nephrology and Dialysis, Department of Internal Medicine III, Medical University of Vienna, 1090 Vienna, Austria., Klas K; Applied Immunology Laboratory, Department of Thoracic Surgery, Medical University of Vienna, 1090 Vienna, Austria.; Aposcience AG, 1200 Vienna, Austria., Direder M; Applied Immunology Laboratory, Department of Thoracic Surgery, Medical University of Vienna, 1090 Vienna, Austria.; Aposcience AG, 1200 Vienna, Austria.; Department of Orthopedics and Trauma Surgery, Medical University of Vienna, 1090 Vienna, Austria., Kühtreiber H; Applied Immunology Laboratory, Department of Thoracic Surgery, Medical University of Vienna, 1090 Vienna, Austria.; Aposcience AG, 1200 Vienna, Austria., Salek M; Applied Immunology Laboratory, Department of Thoracic Surgery, Medical University of Vienna, 1090 Vienna, Austria.; Aposcience AG, 1200 Vienna, Austria., Zur Nedden S; Institute of Neurobiochemistry, CCB-Biocenter, Medical University of Innsbruck, 6020 Innsbruck, Austria., Baier-Bitterlich G; Institute of Neurobiochemistry, CCB-Biocenter, Medical University of Innsbruck, 6020 Innsbruck, Austria., Kiechl S; Department of Neurology, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.; VASCage, Research Centre on Vascular Ageing and Stroke, 6020 Innsbruck, Austria., Haider C; Division of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna, 1090 Vienna, Austria., Endmayr V; Division of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna, 1090 Vienna, Austria., Höftberger R; Division of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna, 1090 Vienna, Austria., Ankersmit HJ; Applied Immunology Laboratory, Department of Thoracic Surgery, Medical University of Vienna, 1090 Vienna, Austria.; Aposcience AG, 1200 Vienna, Austria., Mildner M; Department of Dermatology, Medical University of Vienna, 1090 Vienna, Austria.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Dec 26. Date of Electronic Publication: 2023 Dec 26.