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Zinc Complexes with Nitrogen Donor Ligands as Anticancer Agents

Autor: Porchia M., Pellei M., Del Bello F., Santini C.

Publikováno v: Prime Archives in Molecular Sciences: 2nd Edition., edited by Letizia Giampietro, 2021
info:cnr-pdr/source/autori:Porchia M.; Pellei M., Del Bello F.; Santini C./titolo:Zinc Complexes with Nitrogen Donor Ligands as Anticancer Agents/titolo_volume:Prime Archives in Molecular Sciences: 2nd Edition./curatori_volume:Letizia Giampietro/editore:/anno:2021

The search for anticancer metal-based drugs alternative to platinum derivatives could not exclude zinc derivatives due to the importance of this metal for the correct functioning of the human body. Zinc, the second most abundant trace element in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::84806ecf5f2c10a1314cca8fabe789fa
https://publications.cnr.it/doc/453630

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Zinc coordination complexes as anticancer agents

Autor: Pellei M., Del Bello F., Porchia M., Santini C.

Publikováno v: Coordination chemistry reviews
445 (2021). doi:10.1016/j.ccr.2021.214088 0010-8545
info:cnr-pdr/source/autori:Pellei M.;Del Bello F.; Porchia M.; Santini C./titolo:Zinc coordination complexes as anticancer agents/doi:10.1016%2Fj.ccr.2021.214088 0010-8545/rivista:Coordination chemistry reviews (Print)/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:445

Zinc, present in all forms of life, is an essential element for humans. It is one of the most abundant metals in our body. Because of its importance, any malfunctions of its homeostasis can lead to different disease states, also related to the develo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::8e1661d35909c16325aa6b4cb3ed62cf
https://publications.cnr.it/doc/455352

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From tetrahedrical homoleptic phosphino copper (I) complexes [CuP4]+ to low coordinated species: effect on the antiproliferative activity

Autor: Porchia M., Tisato F., Marzano C., Gandin V., De Franco M.

Publikováno v: XIX Workshop su PharmacoBioMetallics-BioMet 2020, Ancona (Italy), 20-21/02/2020
info:cnr-pdr/source/autori:Porchia M.; Tisato F.; Marzano C.; Gandin V.; De Franco M./congresso_nome:XIX Workshop su PharmacoBioMetallics-BioMet 2020/congresso_luogo:Ancona (Italy)/congresso_data:20-21%2F02%2F2020/anno:2020/pagina_da:/pagina_a:/intervallo_pagine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::0b6b7f5cebe2d6a57c91d6b5e235b386
https://www.biomet2020.it/

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Gold nanorods - copper(I) complexes conjugates as anticancer drug-delivery system

Autor: Venditti I., Battocchio C., Tortora L., Iucci G., Marsotto M., Porchia M., Tisato F., Pellei M., Santini C.

Publikováno v: XIX Workshop su PharmacoBioMetallics-BioMet 2020, Ancona (Italy), 20-21/02/2020
info:cnr-pdr/source/autori:Venditti I.; Battocchio C.; Tortora L.; Iucci G.; Marsotto M.; Porchia M.; Tisato F.; Pellei M.; Santini C./congresso_nome:XIX Workshop su PharmacoBioMetallics-BioMet 2020/congresso_luogo:Ancona (Italy)/congresso_data:20-21%2F02%2F2020/anno:2020/pagina_da:/pagina_a:/intervallo_pagine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::de22122e1439c81301b0f087331746a5
https://www.biomet2020.it/

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ESI(+)MS and DFT studies on the internalization of copper in tumour cells: copper(II)/copper(I) interplay at the hCtr1 substrate

Autor: Tisato F., Porchia M., Carlotto S., Casarin M., Bonna B., Bossak-Ahmad K., Bal W., Traldi P.

Publikováno v: 37th Informal Meeting on Mass Spectrometry---37th IMMS 2019, pp. 20–21, Fiera di Primiero (TN), 05-08/05/2019
info:cnr-pdr/source/autori:Tisato F.; Porchia M.; Carlotto S.; Casarin M.; Bonna B.; Bossak-Ahmad K.; Bal W. ; Traldi P./congresso_nome:37th Informal Meeting on Mass Spectrometry---37th IMMS 2019/congresso_luogo:Fiera di Primiero (TN)/congresso_data:05-08%2F05%2F2019/anno:2019/pagina_da:20/pagina_a:21/intervallo_pagine:20–21

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::abeffd89b0ba0cb9476b9b28c2156025
http://www.cnr.it/prodotto/i/405049

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Cu(I) Complexes Bearing Phosphines Derived From Hydrophilic SarGly -Physicochemical and Biological Characteristics

Autor: Komarnicka U. K., Kozie? S., Zabierowski P., Kruszy?ski R., Lesiów M. K., Tisato F., Porchia M., Kyzio? A.

Publikováno v: ISABC15-15th International Symposium on Applied Bioinorganic Chemistry, Nara (Japan), 02-05/05/2019
info:cnr-pdr/source/autori:Komarnicka U. K.; Kozie? S.; Zabierowski P.; Kruszy?ski R.; Lesiów M. K.; Tisato F.; Porchia M.; Kyzio? A./congresso_nome:ISABC15-15th International Symposium on Applied Bioinorganic Chemistry/congresso_luogo:Nara (Japan)/congresso_data:02-05%2F05%2F2019/anno:2019/pagina_da:/pagina_a:/intervallo_pagine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::65f2b4f474c3fc090cf1176007c97acd
http://www.cnr.it/prodotto/i/405754

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Neutral and charged copper(I) complexes on hydrophilic gold nanoparticles and nanorods: loading and structural studies for biomedical applications

Autor: Venditti, I., Battocchio, C., Fratoddi, I., Iucci, G., Secchi, V., Porchia, M., Tisato, F., Pellei, M., Santini, C.

Publikováno v: XVIII Workshop Pharmabiometallics = BioMet2019, pp. 55–55, Arezzo, 22-23/02/2019
info:cnr-pdr/source/autori:Venditti I.; Battocchio C.; Fratoddi I.; Iucci G.; Secchi V.; Porchia M.; Tisato F.; Pellei M.; Santini C./congresso_nome:XVIII Workshop Pharmabiometallics = BioMet2019/congresso_luogo:Arezzo/congresso_data:22-23%2F02%2F2019/anno:2019/pagina_da:55/pagina_a:55/intervallo_pagine:55–55

In this framework AuNPs and AuNRs were synthetized with the aim to obtain strongly hydrophilic materials, suitable for drug delivery.[4-6] AuNPs were used as drug delivery systems for two different copper(I)-based anti-tumor complexes namely [Cu(PTA)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::885b24e7ab88d8db75d9c557b1bfafe2
https://publications.cnr.it/doc/401717

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Synthesis, reactivity and cytotoxic properties of water soluble coinage metal N-Heterocyclic Carbene complexes

Autor: Bagnarelli L., Santini C., Porchia M., Tisato F., Marzano C., Gandin V., Pellei M.

Publikováno v: XVIII Workshop Pharmabiometallics = BioMet2019, pp. 33–33, Arezzo, 22-23/02/2019
info:cnr-pdr/source/autori:Bagnarelli L.; Santini C.; Porchia M.; Tisato F.; Marzano C.; Gandin V.; Pellei M./congresso_nome:XVIII Workshop Pharmabiometallics = BioMet2019/congresso_luogo:Arezzo/congresso_data:22-23%2F02%2F2019/anno:2019/pagina_da:33/pagina_a:33/intervallo_pagine:33–33

Recently we have focused the research work on 11th group metal-NHCs complexes obtained from water soluble 1,3-symmetrically and 1,3-unsymmetrically substituted NHCs precursors based on imidazole and benzoimidazole scaffolds4-6...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::fca366117ebb8cf485195ea7ab0caa92
http://hdl.handle.net/11581/424135

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Synthesis and characterization of mixed-ligand Zn(II) and Cu(II) complexes including polyamines and dicyanodithiolate: in vitro cytotoxic activity of Cu(II) compounds

Autor: Porchia M., Adhikari S., Bhattacharjee T., Butcher R.J., Tisato F., Nodari L., De Franco M., Gandin V.

Publikováno v: XVIII Workshop Pharmabiometallics = BioMet2019, pp. 44–44, Arezzo, 22-23/02/2019
info:cnr-pdr/source/autori:Porchia M.; Adhikari S.; Bhattacharjee T.; Butcher R.J.; Tisato F.; Nodari L.; De Franco M.; Gandin V./congresso_nome:XVIII Workshop Pharmabiometallics = BioMet2019/congresso_luogo:Arezzo/congresso_data:22-23%2F02%2F2019/anno:2019/pagina_da:44/pagina_a:44/intervallo_pagine:44–44

Potentially bi-, tri- and tetra-dentate polyamines (1,3-diaminopropane (pn); diethylenetriamine (tren), tris(2-aminoethyl)amine (tetraen)) react with divalent zinc and copper nitrate salts in the presence of the 1,1-dicyano-2,2-ethylenedithiolate dip

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::d1fc8ce651bba51c12990952e87beee1
https://publications.cnr.it/doc/401718

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Hydrophilic gold nanoparticles and nanorods as drug delivery systems for anticancer copper complexes

Autor: Venditti, I., Porchia, M., Tisato, F., Santini, C., Pellei, M., Fratoddi, I, Testa, G., Iucci, G., Secchi, V., Battocchio, C.

Publikováno v: XVII Workshop su PharmacoBioMetallics-BioMet 2018, Napoli, 16-17/02/2018
info:cnr-pdr/source/autori:Venditti I.; Porchia M.; Tisato F.; Santini C.; Pellei M.; Fratoddi I.; Testa G.; Iucci G.; Secchi V.; Battocchio C/congresso_nome:XVII Workshop su PharmacoBioMetallics-BioMet 2018/congresso_luogo:Napoli/congresso_data:16-17%2F02%2F2018/anno:2018/pagina_da:/pagina_a:/intervallo_pagine
XVII Workshop Pharmabiometallics-BioMet2018, pp. 45, napoli, 16-17/02/2018
info:cnr-pdr/source/autori:Venditti I.; Porchia M.; Tisato F.; Santini C.; Pellei M.; Fratoddi I.; Testa G.; Iucci G.; Secchi V.; Battocchio C./congresso_nome:XVII Workshop Pharmabiometallics-BioMet2018/congresso_luogo:napoli/congresso_data:16-17%2F02%2F2018/anno:2018/pagina_da:45/pagina_a:/intervallo_pagine:45

In this framework we report a study about drug delivery systems based on functi onalized AuNPs or AuNRs.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1395bd3373796b01b98f304d5729294a
https://publications.cnr.it/doc/422856

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