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The structure of the Shiga toxin 2a A‐subunit dictates the interactions of the toxin with blood components

Autor: Brigotti M., Orth-Holler D., Carnicelli D., Porcellini E., Galassi E., Tazzari P. L., Ricci F., Manoli F., Manet I., Talasz H., Lindner H. H., Speth C., Erbeznik T., Fuchs S., Posch W., Chatterjee S., Wurzner R.

Publikováno v: Cellular Microbiology
Cellular microbiology
(2019). doi:10.1111/cmi.13000
info:cnr-pdr/source/autori:Brigotti M.; Orth-Holler D.; Carnicelli D.; Porcellini E.; Galassi E.; Tazzari P.L.; Ricci F.; Manoli F.; Manet I.; Talasz H.; Lindner H.H.; Speth C.; Erbeznik T.; Fuchs S.; Posch W.; Chatterjee S.; Wurzner R./titolo:The structure of the Shiga toxin 2a A-subunit dictates the interactions of the toxin with blood components/doi:10.1111%2Fcmi.13000/rivista:Cellular microbiology (Print)/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume

Hemolytic uremic syndrome (eHUS) is a severe complication of human infections with Shiga toxins (Stxs)‐producing Escherichia coli. A key step in the pathogenesis of eHUS is the interaction of Stxs with blood components before the targeting of renal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::52af7ab0d9bda8eee7dde384162e2d5d
http://europepmc.org/articles/PMC6492301

Genome-wide association study indentifies variants at CLU and CR1 associated with Alzheimer’s disease

Autor: Lambert JC, Heath S, Even G, Campion D, Sleegers K, Hiltunen M, Combarros O, Zelenika D, Bullido MJ, Tavernier B, Letenneur L, Bettens K, Berr C, Pasquier F, Fiévet N, Barberger-Gateau P, Engelborghs S, De Deyn P, Mateo I, Franck A, Helisalmi S, Porcellini E, Hanon O, European Alzheimer's Disease Initiative Investigators, de Pancorbo MM, Lendon C, Dufouil C, Jaillard C, Leveillard T, Alvarez V, Bosco P, Mancuso M, Panza F, Nacmias B, Bossù P, Piccardi P, Annoni G, Seripa D, Galimberti D, Hannequin D, Licastro F, Soininen H, Ritchie K, Blanché H, Dartigues JF, Tzourio C, Gut I, Van Broeckhoven C, Alpérovitch A, Lathrop M, Amouyel P, FORTI, PAOLA

Publikováno v: Nature genetics

The gene encoding apolipoprotein E (APOE) on chromosome 19 is the only confirmed susceptibility locus for late-onset Alzheimer's disease. To identify other risk loci, we conducted a large genome-wide association study of 2,032 individuals from France

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e16990d3e5991d9bc0ff2e91a3e3ebd
http://hdl.handle.net/10281/9031

The CALHM1 P86L polymorphism is a genetic modifier of age at onset in Alzheimer's disease: a meta-analysis study

Autor: Lambert, J., Sleegers, K., Gonzalez-Perez, A., Ingelsson, M., Beecham, G., Hiltunen, M., Combarros, O., Bullido, M., Brouwers, N., Bettens, K., Berr, C., Pasquier, F., Richard, F., Dekosky, S., Hannequin, D., Haines, J., Tognoni, G., Fievet, N., Dartigues, J., Tzourio, C., Engelborghs, S., Arosio, B., Coto, E., De Deyn, P., Del Zompo, M., Mateo, I., Boada, M., Antunez, C., Lopez-Arrieta, J., Epelbaum, J., Schjeide, B., Frank-Garcia, A., Giedraitis, V., Helisalmi, S., Porcellini, E., Pilotto, A., Forti, P., Ferri, R., Delepine, M., Zelenika, D., Lathrop, M., Scarpini, E., Siciliano, G., Solfrizzi, V., Sorbi, S., Spalletta, G., Ravaglia, G., Valdivieso, F., Vepsalainen, S., Alvarez, V., Bosco, P., Mancuso, M., Panza, F., Nacmias, B., Bossu, P., Hanon, O., Piccardi, P., Annoni, G., Mann, D., Marambaud, P., Seripa, D., Galimberti, D., Tanzi, R., Bertram, L., Lendon, C., Lannfelt, L., Licastro, F., Campion, D., Pericak-Vance, M., Soininen, H., Van Broeckhoven, C., Alperovitch, A., Ruiz, A., Kamboh, M., Amouyel, P.

Publikováno v: J Alzheimers Dis

The only established genetic determinant of non-Mendelian forms of Alzheimer's disease (AD) is the epsilon4 allele of the apolipoprotein E gene (APOE). Recently, it has been reported that the P86L polymorphism of the calcium homeostasis modulator 1 g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1874::7aa92d6380c3b3df95280a808e920a4b
https://hdl.handle.net/11858/00-001M-0000-0010-7C98-911858/00-001M-0000-0010-7C97-B

Dal PDM al QFM-27: un tentativo di sistematizzazione della valutazione del funzionamento mentale e dei livelli evolutivi della personalità secondo il manuale diagnostico psicodinamico (PDM)

Autor: Albasi, Cesare, Lasorsa, Claudia, Porcellini, E.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______970::a8d5e62a1bf0910e76584b06ca81639b
http://hdl.handle.net/2318/60008