Unveiling the dynamics and molecular landscape of a rare chronic lymphocytic leukemia subpopulation driving refractoriness: insights from single-cell RNA sequencing.

Autor: Kurucova T; Central European Institute of Technology, Center of Molecular Medicine, Masaryk University, Brno, Czech Republic.; Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic., Reblova K; Central European Institute of Technology, Center of Molecular Medicine, Masaryk University, Brno, Czech Republic.; Department of Internal Medicine, Hematology and Oncology, Faculty of Medicine, Masaryk University and University Hospital Brno, Czech Republic., Janovska P; Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic., Porc JP; Central European Institute of Technology, Center of Molecular Medicine, Masaryk University, Brno, Czech Republic.; Institute of Medical Genetics and Genomics, Faculty of Medicine, Masaryk University and University Hospital Brno, Czech Republic., Navrkalova V; Central European Institute of Technology, Center of Molecular Medicine, Masaryk University, Brno, Czech Republic.; Department of Internal Medicine, Hematology and Oncology, Faculty of Medicine, Masaryk University and University Hospital Brno, Czech Republic.; Institute of Medical Genetics and Genomics, Faculty of Medicine, Masaryk University and University Hospital Brno, Czech Republic., Pavlova S; Central European Institute of Technology, Center of Molecular Medicine, Masaryk University, Brno, Czech Republic.; Department of Internal Medicine, Hematology and Oncology, Faculty of Medicine, Masaryk University and University Hospital Brno, Czech Republic.; Institute of Medical Genetics and Genomics, Faculty of Medicine, Masaryk University and University Hospital Brno, Czech Republic., Malcikova J; Central European Institute of Technology, Center of Molecular Medicine, Masaryk University, Brno, Czech Republic.; Department of Internal Medicine, Hematology and Oncology, Faculty of Medicine, Masaryk University and University Hospital Brno, Czech Republic.; Institute of Medical Genetics and Genomics, Faculty of Medicine, Masaryk University and University Hospital Brno, Czech Republic., Plevova K; Central European Institute of Technology, Center of Molecular Medicine, Masaryk University, Brno, Czech Republic.; Department of Internal Medicine, Hematology and Oncology, Faculty of Medicine, Masaryk University and University Hospital Brno, Czech Republic.; Institute of Medical Genetics and Genomics, Faculty of Medicine, Masaryk University and University Hospital Brno, Czech Republic., Tichy B; Central European Institute of Technology, Center of Molecular Medicine, Masaryk University, Brno, Czech Republic.; Institute of Medical Genetics and Genomics, Faculty of Medicine, Masaryk University and University Hospital Brno, Czech Republic., Doubek M; Central European Institute of Technology, Center of Molecular Medicine, Masaryk University, Brno, Czech Republic.; Department of Internal Medicine, Hematology and Oncology, Faculty of Medicine, Masaryk University and University Hospital Brno, Czech Republic.; Institute of Medical Genetics and Genomics, Faculty of Medicine, Masaryk University and University Hospital Brno, Czech Republic., Bryja V; Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic., Kotaskova J; Central European Institute of Technology, Center of Molecular Medicine, Masaryk University, Brno, Czech Republic.; Department of Internal Medicine, Hematology and Oncology, Faculty of Medicine, Masaryk University and University Hospital Brno, Czech Republic.; Institute of Medical Genetics and Genomics, Faculty of Medicine, Masaryk University and University Hospital Brno, Czech Republic., Pospisilova S; Central European Institute of Technology, Center of Molecular Medicine, Masaryk University, Brno, Czech Republic.; Department of Internal Medicine, Hematology and Oncology, Faculty of Medicine, Masaryk University and University Hospital Brno, Czech Republic.; Institute of Medical Genetics and Genomics, Faculty of Medicine, Masaryk University and University Hospital Brno, Czech Republic.

Publikováno v: Molecular oncology [Mol Oncol] 2024 Oct; Vol. 18 (10), pp. 2541-2553. Date of Electronic Publication: 2024 May 21.