Population pharmacokinetic-pharmacodynamic model of propofol in adolescents undergoing scoliosis surgery with intraoperative wake-up test: a study using Bispectral index and composite auditory evoked potentials as pharmacodynamic endpoints

Autor: Heleen J. Blussé van Oud-Alblas, Margreke J. E. Brill, Mariska Y. M. Peeters, Dick Tibboel, Meindert Danhof, Catherijne A. J. Knibbe

Publikováno v: BMC Anesthesiology, Vol 19, Iss 1, Pp 1-12 (2019)

Abstract Background In adolescents limited data are available on the pharmacokinetics (PK) and pharmacodynamics (PD) of propofol. In this study we derived a PK-PD model for propofol in adolescents undergoing idiopathic scoliosis surgery with an intra

Externí odkaz: https://doaj.org/article/2e21509f15884249a1bf9c8f16b20547

Population pharmacokinetic-pharmacodynamic model of propofol in adolescents undergoing scoliosis surgery with intraoperative wake-up test: a study using Bispectral index and composite auditory evoked potentials as pharmacodynamic endpoints

Autor: Margreke J. E. Brill, Heleen J. Blussé van Oud-Alblas, Meindert Danhof, Mariska Y. M. Peeters, Catherijne A. J. Knibbe, Dick Tibboel

Publikováno v: BMC Anesthesiology, 19, 15. BMC
BMC Anesthesiology, Vol 19, Iss 1, Pp 1-12 (2019)
BMC Anesthesiology, 19(1). BioMed Central Ltd.
BMC Anesthesiology

Background: In adolescents limited data are available on the pharmacokinetics (PK) and pharmacodynamics (PD) of propofol. In this study we derived a PK-PD model for propofol in adolescents undergoing idiopathic scoliosis surgery with an intraoperativ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f50f191e2f26f90b50364d7a823f07
https://pure.eur.nl/en/publications/22441164-3719-4cbf-a64e-bab7a43e866d

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