Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Poppy Sephton-Clark"'
Autor:
Poppy Sephton-Clark, Jennifer L. Tenor, Dena L. Toffaletti, Nancy Meyers, Charles Giamberardino, Síle F. Molloy, Julia R. Palmucci, Adrienne Chan, Tarsizio Chikaonda, Robert Heyderman, Mina Hosseinipour, Newton Kalata, Cecilia Kanyama, Christopher Kukacha, Duncan Lupiya, Henry C. Mwandumba, Thomas Harrison, Tihana Bicanic, John R. Perfect, Christina A. Cuomo
Publikováno v:
mBio, Vol 13, Iss 6 (2022)
ABSTRACT Cryptococcus neoformans is the causative agent of cryptococcosis, a disease with poor patient outcomes that accounts for approximately 180,000 deaths each year. Patient outcomes may be impacted by the underlying genetics of the infecting iso
Externí odkaz:
https://doaj.org/article/2422d58ac858444989d662505ee09ad6
Autor:
Chen-Hsin Yu, Poppy Sephton-Clark, Jennifer L. Tenor, Dena L. Toffaletti, Charles Giamberardino, Miriam Haverkamp, Christina A. Cuomo, John R. Perfect
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
ABSTRACT Cryptococcus neoformans is a major human central nervous system (CNS) fungal pathogen causing considerable morbidity and mortality. In this study, we provide the widest view to date of the yeast transcriptome directly from the human subarach
Externí odkaz:
https://doaj.org/article/9b9ded657eed4fd6aa3fd551f0086496
Autor:
Poppy Sephton-Clark, Thu Nguyen, Ngo Thi Hoa, Philip Ashton, H. Rogier van Doorn, Vo Trieu Ly, Thuy Le, Christina A. Cuomo
Publikováno v:
bioRxiv
Talaromycosis, a severe and invasive fungal infection caused byTalaromyces marneffei, is difficult to treat and impacts those living in endemic regions of southeast Asia, India, and China. While 30% of infections result in mortality, our understandin
Autor:
Poppy, Sephton-Clark, Scott A, McConnell, Nina, Grossman, Rosanna P, Baker, Quigly, Dragotakes, Yunfan, Fan, Man Shun, Fu, Gracen, Gerbig, Seth, Greengo, J Marie, Hardwick, Madhura, Kulkarni, Stuart M, Levitz, Joshua D, Nosanchuk, Shmuel, Shoham, Daniel F Q, Smith, Piotr, Stempinski, Winston, Timp, Maggie P, Wear, Christina A, Cuomo, Arturo, Casadevall
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 120(2)
A pet cockatoo was the suspected source of
Autor:
Hans Carolus, Dimitrios Sofras, Poppy Sephton-Clark, Louise Goossens, Alicia Chen, Siebe Pierson, Celia Lobo Romero, Ana Subotić, Jacques F. Meis, Christina A. Cuomo, Patrick Van Dijck
Publikováno v:
Medical Mycology. 60
S2.5 Rare yeasts, September 21, 2022, 3:00 PM - 4:30 PM Candida auris (C. auris) is a recently emerged human fungal pathogen of growing concern due to its ability to acquire extensive multidrug resistance (MDR) to all four antifungal drug classes. Th
Autor:
Poppy Sephton-Clark, Scott A. McConnell, Nina Grossman, Rosanna Baker, Quigly Dragotakes, Yunfan Fan, Man Shun Fu, Gracen Gerbig, Seth Greengo, J. Marie Hardwick, Madhura Kulkarni, Stuart M. Levitz, Joshua D. Nosanchuk, Shmuel Shoham, Daniel Smith, Piotr Stempinski, Maggie Wear, Christina A. Cuomo, Arturo Casadevall
A pet cockatoo was the suspected source of Cryptococcus neoformans recovered from the cerebral spinal fluid (CSF) of an immunocompromised patient with cryptococcosis based on the molecular analyses available in 2000. Here we report whole genome seque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fb5576573f81bcdf0b286f1a2d45251
https://doi.org/10.1101/2022.04.12.487930
https://doi.org/10.1101/2022.04.12.487930
Autor:
Jennifer L. Tenor, Chen-Hsin Yu, Poppy Sephton-Clark, Dena L. Toffaletti, Charles Giamberardino, John R. Perfect, Miriam Haverkamp, Christina A. Cuomo
Publikováno v:
mBio
mBio, Vol 12, Iss 6 (2021)
mBio, Vol 12, Iss 6 (2021)
Cryptococcus neoformans is a major human central nervous system (CNS) fungal pathogen causing considerable morbidity and mortality. In this study, we provide the widest view to date of the yeast transcriptome directly from the human subarachnoid spac
Autor:
Xin Zhou, Hanna Zafar, Poppy Sephton-Clark, Sally H. Mohamed, Ambre Chapuis, Maria Makarova, Donna M. MacCallum, Rebecca A. Drummond, Ivy M. Dambuza, Elizabeth R. Ballou
Fungal morphology significantly impacts the host response. Filamentation and tissue penetration by Candida and Aspergillus species are essential for virulence, while growth as a yeast allows the thermal dimorphic fungi Coccidiodes, Histoplasma, and T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8b616ce2680abb868206efabe6ab2f4
https://doi.org/10.1101/2020.01.03.894709
https://doi.org/10.1101/2020.01.03.894709
Autor:
Christina A. Cuomo, Michelle E Matzko, Melanie A Martinsen, Roby P. Bhattacharyya, Poppy Sephton-Clark
Publikováno v:
Open Forum Infectious Diseases
Background A rapid and accurate diagnostic method for invasive fungal infections remains a critical clinical need. We recently reported a rapid molecular method for bacterial species identification directly from clinical samples that targets highly a
Rhizopus delemar is an invasive fungal pathogen, responsible for the frequently fatal disease mucormycosis. Germination, a crucial mechanism by which spores of Rhizopus delemar infect and cause disease, is a key developmental process that transforms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b754cc0d0cadca41af5eb6f3fddfe47
https://doi.org/10.1101/330969
https://doi.org/10.1101/330969