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Akademický článek

Nitrogen-Containing Heterocyclic Compounds Obtained from Monoterpenes or Their Derivatives: Synthesis and Properties.

Autor: Chernyshov VV; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, Lavrent'ev av., 9, Novosibirsk, 630090, Russian Federation. vladimir.chernyshov2012@yandex.ru.; Novosibirsk State University, Pirogova St. 1, 630090, Novosibirsk, Russian Federation. vladimir.chernyshov2012@yandex.ru., Popadyuk II; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, Lavrent'ev av., 9, Novosibirsk, 630090, Russian Federation.; Novosibirsk State University, Pirogova St. 1, 630090, Novosibirsk, Russian Federation., Yarovaya OI; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, Lavrent'ev av., 9, Novosibirsk, 630090, Russian Federation.; Novosibirsk State University, Pirogova St. 1, 630090, Novosibirsk, Russian Federation., Salakhutdinov NF; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, Lavrent'ev av., 9, Novosibirsk, 630090, Russian Federation.; Novosibirsk State University, Pirogova St. 1, 630090, Novosibirsk, Russian Federation.

Publikováno v: Topics in current chemistry (Cham) [Top Curr Chem (Cham)] 2022 Aug 11; Vol. 380 (5), pp. 42. Date of Electronic Publication: 2022 Aug 11.

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Akademický článek

Novel O-acylated amidoximes and substituted 1,2,4-oxadiazoles synthesised from (+)-ketopinic acid possessing potent virus-inhibiting activity against phylogenetically distinct influenza A viruses.

Autor: Chernyshov VV; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, Lavrent'ev av., 9, Novosibirsk 630090, Russia., Yarovaya OI; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, Lavrent'ev av., 9, Novosibirsk 630090, Russia. Electronic address: ooo@nioch.nsc.ru., Esaulkova IL; Saint-Petersburg Pasteur Institute, 14 Mira str., 197101 St. Petersburg, Russia., Sinegubova E; Saint-Petersburg Pasteur Institute, 14 Mira str., 197101 St. Petersburg, Russia., Borisevich SS; Ufa Institute of Chemistry, Ufa Federal Research Center, RAS, Octyabrya pr., 71, Ufa 450054, Russia., Popadyuk II; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, Lavrent'ev av., 9, Novosibirsk 630090, Russia., Zarubaev VV; Saint-Petersburg Pasteur Institute, 14 Mira str., 197101 St. Petersburg, Russia., Salakhutdinov NF; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, Lavrent'ev av., 9, Novosibirsk 630090, Russia.

Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2022 Jan 01; Vol. 55, pp. 128465. Date of Electronic Publication: 2021 Nov 19.

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Akademický článek

New Deoxycholic Acid Derived Tyrosyl-DNA Phosphodiesterase 1 Inhibitors Also Inhibit Tyrosyl-DNA Phosphodiesterase 2.

Autor: Salomatina OV; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, SB RAS, 9, Lavrent'ev Ave., 630090 Novosibirsk, Russia., Dyrkheeva NS; Institute of Chemical Biology and Fundamental Medicine, SB RAS, 8, Lavrent'ev Ave., 630090 Novosibirsk, Russia., Popadyuk II; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, SB RAS, 9, Lavrent'ev Ave., 630090 Novosibirsk, Russia., Zakharenko AL; Institute of Chemical Biology and Fundamental Medicine, SB RAS, 8, Lavrent'ev Ave., 630090 Novosibirsk, Russia., Ilina ES; Institute of Chemical Biology and Fundamental Medicine, SB RAS, 8, Lavrent'ev Ave., 630090 Novosibirsk, Russia., Komarova NI; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, SB RAS, 9, Lavrent'ev Ave., 630090 Novosibirsk, Russia., Reynisson J; School of Pharmacy and Bioengineering, Keele University, Staffordshire ST5 5BG, UK., Salakhutdinov NF; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, SB RAS, 9, Lavrent'ev Ave., 630090 Novosibirsk, Russia., Lavrik OI; Institute of Chemical Biology and Fundamental Medicine, SB RAS, 8, Lavrent'ev Ave., 630090 Novosibirsk, Russia., Volcho KP; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, SB RAS, 9, Lavrent'ev Ave., 630090 Novosibirsk, Russia.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2021 Dec 23; Vol. 27 (1). Date of Electronic Publication: 2021 Dec 23.

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Akademický článek

Deoxycholic acid as a molecular scaffold for tyrosyl-DNA phosphodiesterase 1 inhibition: A synthesis, structure-activity relationship and molecular modeling study.

Autor: Salomatina OV; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, SB RAS, 9, Lavrent'ev Ave., Novosibirsk 630090, Russian Federation. Electronic address: ana@nioch.nsc.ru., Popadyuk II; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, SB RAS, 9, Lavrent'ev Ave., Novosibirsk 630090, Russian Federation., Zakharenko AL; Institute of Chemical Biology and Fundamental Medicine, SB RAS, 8, Lavrent'ev Ave., Novosibirsk 630090, Russian Federation., Zakharova OD; Institute of Chemical Biology and Fundamental Medicine, SB RAS, 8, Lavrent'ev Ave., Novosibirsk 630090, Russian Federation., Chepanova AA; Institute of Chemical Biology and Fundamental Medicine, SB RAS, 8, Lavrent'ev Ave., Novosibirsk 630090, Russian Federation., Dyrkheeva NS; Institute of Chemical Biology and Fundamental Medicine, SB RAS, 8, Lavrent'ev Ave., Novosibirsk 630090, Russian Federation., Komarova NI; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, SB RAS, 9, Lavrent'ev Ave., Novosibirsk 630090, Russian Federation., Reynisson J; School of Pharmacy and Bioengineering, Keele University, Hornbeam Building, Staffordshire ST5 5BG, UK., Anarbaev RO; Institute of Chemical Biology and Fundamental Medicine, SB RAS, 8, Lavrent'ev Ave., Novosibirsk 630090, Russian Federation., Salakhutdinov NF; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, SB RAS, 9, Lavrent'ev Ave., Novosibirsk 630090, Russian Federation., Lavrik OI; Institute of Chemical Biology and Fundamental Medicine, SB RAS, 8, Lavrent'ev Ave., Novosibirsk 630090, Russian Federation., Volcho KP; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, SB RAS, 9, Lavrent'ev Ave., Novosibirsk 630090, Russian Federation.

Publikováno v: Steroids [Steroids] 2021 Jan; Vol. 165, pp. 108771. Date of Electronic Publication: 2020 Nov 19.

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Akademický článek

Novel 3'-Substituted-1',2',4'-Oxadiazole Derivatives of 18βH-Glycyrrhetinic Acid and Their O -Acylated Amidoximes: Synthesis and Evaluation of Antitumor and Anti-Inflammatory Potential In Vitro and In Vivo.

Autor: Markov AV; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Lavrent'ev ave., 8, 630090 Novosibirsk, Russia., Sen'kova AV; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Lavrent'ev ave., 8, 630090 Novosibirsk, Russia., Popadyuk II; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, Lavrent'ev ave., 9, 630090 Novosibirsk, Russia., Salomatina OV; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Lavrent'ev ave., 8, 630090 Novosibirsk, Russia.; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, Lavrent'ev ave., 9, 630090 Novosibirsk, Russia., Logashenko EB; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Lavrent'ev ave., 8, 630090 Novosibirsk, Russia., Komarova NI; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, Lavrent'ev ave., 9, 630090 Novosibirsk, Russia., Ilyina AA; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Lavrent'ev ave., 8, 630090 Novosibirsk, Russia., Salakhutdinov NF; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, Lavrent'ev ave., 9, 630090 Novosibirsk, Russia., Zenkova MA; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Lavrent'ev ave., 8, 630090 Novosibirsk, Russia.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2020 May 15; Vol. 21 (10). Date of Electronic Publication: 2020 May 15.

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Akademický článek

Novel Derivatives of Deoxycholic Acid Bearing Linear Aliphatic Diamine and Aminoalcohol Moieties and their Cyclic Analogs at the C3 Position: Synthesis and Evaluation of Their In Vitro Antitumor Potential.

Autor: Markov AV; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Lavrent'ev ave., 8, 630090 Novosibirsk, Russia. andmrkv@gmail.com., Babich VO; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Lavrent'ev ave., 8, 630090 Novosibirsk, Russia.; Novosibirsk State University, Pirogova str. 2, 630090 Novosibirsk, Russia., Popadyuk II; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, Lavrent'ev ave., 9, 630090 Novosibirsk, Russia., Salomatina OV; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Lavrent'ev ave., 8, 630090 Novosibirsk, Russia.; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, Lavrent'ev ave., 9, 630090 Novosibirsk, Russia., Logashenko EB; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Lavrent'ev ave., 8, 630090 Novosibirsk, Russia., Salakhutdinov NF; Novosibirsk State University, Pirogova str. 2, 630090 Novosibirsk, Russia.; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, Lavrent'ev ave., 9, 630090 Novosibirsk, Russia., Zenkova MA; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Lavrent'ev ave., 8, 630090 Novosibirsk, Russia.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2019 Jul 21; Vol. 24 (14). Date of Electronic Publication: 2019 Jul 21.

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Akademický článek

Novel Semisynthetic Derivatives of Bile Acids as Effective Tyrosyl-DNA Phosphodiesterase 1 Inhibitors.

Autor: Salomatina OV; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, SB RAS, acad. Lavrentjev ave. 9, Novosibirsk 630090, Russia. ana@nioch.nsc.ru., Popadyuk II; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, SB RAS, acad. Lavrentjev ave. 9, Novosibirsk 630090, Russia. popadyuk@nioch.nsc.ru., Zakharenko AL; Novosibirsk Institute of Chemical Biology and Fundamental Medicine, SB RAS, acad. Lavrentjev ave. 8, Novosibirsk 630090, Russia. sashaz@niboch.nsc.ru., Zakharova OD; Novosibirsk Institute of Chemical Biology and Fundamental Medicine, SB RAS, acad. Lavrentjev ave. 8, Novosibirsk 630090, Russia. isar@niboch.nsc.ru., Fadeev DS; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, SB RAS, acad. Lavrentjev ave. 9, Novosibirsk 630090, Russia. dsf@nioch.nsc.ru., Komarova NI; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, SB RAS, acad. Lavrentjev ave. 9, Novosibirsk 630090, Russia. komar@nioch.nsc.ru., Reynisson J; School of Chemical Sciences, University of Auckland, Auckland 1142, New Zealand. j.reynisson@auckland.ac.nz., Arabshahi HJ; School of Chemical Sciences, University of Auckland, Auckland 1142, New Zealand. j.arabshahi@auckland.ac.nz., Chand R; School of Chemical Sciences, University of Auckland, Auckland 1142, New Zealand. rcha387@aucklanduni.ac.nz., Volcho KP; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, SB RAS, acad. Lavrentjev ave. 9, Novosibirsk 630090, Russia. volcho@nioch.nsc.ru.; Novosibirsk State University, Pirogova str. 2, Novosibirsk 630090, Russia. volcho@nioch.nsc.ru., Salakhutdinov NF; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, SB RAS, acad. Lavrentjev ave. 9, Novosibirsk 630090, Russia. anvar@nioch.nsc.ru.; Novosibirsk State University, Pirogova str. 2, Novosibirsk 630090, Russia. anvar@nioch.nsc.ru., Lavrik OI; Novosibirsk Institute of Chemical Biology and Fundamental Medicine, SB RAS, acad. Lavrentjev ave. 8, Novosibirsk 630090, Russia. lavrik@niboch.nsc.ru.; Novosibirsk State University, Pirogova str. 2, Novosibirsk 630090, Russia. lavrik@niboch.nsc.ru.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2018 Mar 17; Vol. 23 (3). Date of Electronic Publication: 2018 Mar 17.

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