Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Poorya Parvizi"'
Autor:
Zeliha Gözde Turan, Vincent Richter, Jana Bochmann, Poorya Parvizi, Etka Yapar, Ulas Işıldak, Sarah-Kristin Waterholter, Sabrina Leclere-Turbant, Çağdaş Devrim Son, Charles Duyckaerts, İdil Yet, Thomas Arendt, Mehmet Somel, Uwe Ueberham
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-16 (2022)
Abstract The possible role of somatic copy number variations (CNVs) in Alzheimer’s disease (AD) aetiology has been controversial. Although cytogenetic studies suggested increased CNV loads in AD brains, a recent single-cell whole-genome sequencing
Externí odkaz:
https://doaj.org/article/ba317eb633834c2a8760cce667a8cb1c
SummaryA network embedding approach reduces the analysis complexity of large biological networks by converting them to lowdimensional vector representations (features/embeddings). These lower-dimensional vectors can then be used in machine learning p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13c8b1776e91b1ceeeb93d75c8188e3c
Autor:
Morteza Khaleghi, Zahra Ameri, Alireza Farsinejad, Poorya Parvizi, Reza Vahidi, Masoud Moghadari, Zahra Sheikh Rezaei
Publikováno v:
Indian J Hematol Blood Transfus
The present study aims to investigate the changes in different parameters related to the storage time of red blood cell (RBC) units. Microscopic, flow cytometric, and electrophoretic assessments were employed every few days for 60 days to investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58bd5594a69641b21ec5fe2d3e876466
https://europepmc.org/articles/PMC9001803/
https://europepmc.org/articles/PMC9001803/
Autor:
Gökçe Senger, Ferah Yildirim, Foteini Paraskevopoulou, Poorya Parvizi, Nurcan Tuncbag, Christian Rosenmund
Publikováno v:
Proc Natl Acad Sci U S A
Transcriptional dysregulation in Huntington’s disease (HD) causes functional deficits in striatal neurons. Here, we performed Patch-sequencing (Patch-seq) in an in vitro HD model to investigate the effects of mutant Huntingtin (Htt) on synaptic tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0659d85ad0794e5c4c3021154ae2c7a3
https://doi.org/10.1073/pnas.2020293118
https://doi.org/10.1073/pnas.2020293118
Publikováno v:
Parvizi, P, Azuaje, F, Theodoratou, E & Luz, S 2020, ' A Network-Based Embedding Method for Drug-Target Interaction Prediction ', Paper presented at 2020 42nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) in conjunction with the 43rd Annual Conference of the Canadian Medical and Biological Engineering Society, 20/07/20-24/07/20 pp. 5304-5307 . https://doi.org/10.1109/EMBC44109.2020.9176165
EMBC
EMBC
Integration of multi-omics and pharmacological data can help researchers understand the impact of drugs on dynamic biological systems. Network-based approaches to such integration explore the interaction of different cellular components and drugs. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::264ca00f9c8ff617dc980e316a83c842
https://www.pure.ed.ac.uk/ws/files/164366473/A_Network_Based_Embedding_Method.pdf
https://www.pure.ed.ac.uk/ws/files/164366473/A_Network_Based_Embedding_Method.pdf
Autor:
Poorya Parvizi, Handan Melike Dönertaş, Jenny Tung, Zeliha Gozde Turan, Philipp Khaitovich, Mehmet Somel
Publikováno v:
Aging Cell
Turan, Z G, Parvizi, P, Dönertaş, H M, Tung, J, Khaitovich, P & Somel, M 2019, ' Molecular footprint of Medawar's mutation accumulation process in mammalian aging ', Aging Cell, pp. e12965 . https://doi.org/10.1111/acel.12965
Turan, Z G, Parvizi, P, Dönertaş, H M, Tung, J, Khaitovich, P & Somel, M 2019, ' Molecular footprint of Medawar's mutation accumulation process in mammalian aging ', Aging Cell, pp. e12965 . https://doi.org/10.1111/acel.12965
Medawar's mutation accumulation hypothesis explains aging by the declining force of natural selection with age: Slightly deleterious germline mutations expressed in old age can drift to fixation and thereby lead to aging‐related phenotypes. Althoug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5353a72f0d8e094dcecf63165cf89a89
https://pubmed.ncbi.nlm.nih.gov/31062469
https://pubmed.ncbi.nlm.nih.gov/31062469
Autor:
Handan Melike Dönertaş, Zeliha Gozde Turan, Philipp Khaitovich, Mehmet Somel, Jenny Tung, Poorya Parvizi
Medawar’s mutation accumulation (MA) hypothesis explains ageing by the declining force of natural selection with age: slightly deleterious germline mutations that are functional in old age are not effectively eliminated by selection and therefore l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99581a665657f729c2dced84c66f45b5
Autor:
Reyhan Yaka, Poorya Parvizi, İnci Togan, Sidar Gündüzalp, Aslı Erim Özdoğan, Yasemin Yılmaz, Aysegul Birand, Mehmet Somel, Sinan Can Açan, Ceren Caner
Birand, Aysegul/0000-0001-9217-3627; Parvizi, Poorya/0000-0002-1282-765X WOS: 000430461100014 PubMed: 29399779 ObjectivesNorth Mesopotamia has witnessed dramatic social change during the Holocene, but the impact of these events on its demographic his
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac2f66111f6fd0e7084cf99a9e0acc2f
https://aperta.ulakbim.gov.tr/record/30905
https://aperta.ulakbim.gov.tr/record/30905