Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Poornima Devineni"'
Autor:
Bryan R. Gorman, Sun-Gou Ji, Michael Francis, Anoop K. Sendamarai, Yunling Shi, Poornima Devineni, Uma Saxena, Elizabeth Partan, Andrea K. DeVito, Jinyoung Byun, Younghun Han, Xiangjun Xiao, Don D. Sin, Wim Timens, Jennifer Moser, Sumitra Muralidhar, Rachel Ramoni, Rayjean J. Hung, James D. McKay, Yohan Bossé, Ryan Sun, Christopher I. Amos, VA Million Veteran Program, Saiju Pyarajan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Lung cancer remains the leading cause of cancer mortality, despite declining smoking rates. Previous lung cancer GWAS have identified numerous loci, but separating the genetic risks of lung cancer and smoking behavioral susceptibility remain
Externí odkaz:
https://doaj.org/article/dac86f32ac504f5bbdb7376d6931934e
Autor:
Kyriacos Markianos, Frederic Dong, Bryan Gorman, Yunling Shi, Daniel Dochtermann, Uma Saxena, Poornima Devineni, Jennifer Moser, Sumitra Muralidhar, Rachel Ramoni, Philip Tsao, Saiju Pyarajan, Ronald Przygodzki, Million Veteran Program
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0274339 (2023)
We present allele frequencies of pharmacogenomics relevant variants across multiple ancestry in a sample representative of the US population. We analyzed 658,582 individuals with genotype data and extracted pharmacogenomics relevant single nucleotide
Externí odkaz:
https://doaj.org/article/bca5a95e90da42c3a3c49c3e4f346e91
Autor:
Royce Clifford, Daniel Munro, Daniel Dochtermann, Poornima Devineni, Saiju Pyarajan, Million Veteran Program, Francesca Talese, Abraham A. Palmer, Pejman Mohammadi, Rick Friedman
BackgroundChronic age-related dizziness can arise from dysfunction of the vestibulocochlear system, an elegant neuroanatomical group of pathways that mediates human perception of linear acceleration, gravity, and angular head motion. Studies indicate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f9d7aa6397e0dd532b36c14b75007df
https://doi.org/10.1101/2022.12.14.22283471
https://doi.org/10.1101/2022.12.14.22283471
Autor:
John Concato, Timothy J. O'Leary, Mary Brophy, Lakshmi Radhakrishnan, Jie Huang, Purushotham Karnam, VA Million Veteran Program, Sun-Gou Ji, Haley Hunter-Zinck, Saiju Pyarajan, Man Li, Yunling Shi, Xin Gong, Jennifer Moser, Ronald M. Przygodzki, Philip S. Tsao, Elizabeth R. Hauser, Sumitra Muralidhar, Joel Gelernter, Paul Hsieh, John Michael Gaziano, Ning Sun, Poornima Devineni, Donald E. Humphries, Christopher J. O'Donnell, Hongyu Zhao, Teresa Webster, Themistocles L. Assimes, Grant D. Huang, Jeanette Schmidt, Andrew Liem, Cuiping Pan, Bryan R Gorman
Publikováno v:
Am J Hum Genet
The Million Veteran Program (MVP), initiated by the Department of Veterans Affairs (VA), aims to collect biosamples with consent from at least one million veterans. Presently, blood samples have been collected from over 800,000 enrolled participants.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6551f00af2013674a1d49a2268eea172
https://doi.org/10.1016/j.ajhg.2020.03.004
https://doi.org/10.1016/j.ajhg.2020.03.004
Autor:
Craig Teerlink, David E. Kaplan, Marijana Vujkovic, Benjamin Voight, Kyong-Mi Chang, Julie Lynch, Scott Duvall, Tori Anglin, Timothy Morgan, Linus Schwantes-An Tae-Hwi, Trina Norden-Krichmar, Daniel Dochterman, Poornima Devineni, Philip Tsao, Carolin Victoria Schneider
Publikováno v:
Journal of Hepatology. 77:S30-S31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a23445e98d7760761783067fa342241c
https://doi.org/10.1016/s0168-8278(22)00473-1
https://doi.org/10.1016/s0168-8278(22)00473-1
Autor:
David Kaplan, Marijana Vujkovic, Daniel Dochterman, Kirk Wangensteen, Poornima Devineni, Tae-Hwi Linus Schwantes-An, Anoop Sendamarai, Purushtotham Karnam, Emily Sileo, Tori Anglin, Trina Norden-Krichmar, Philip Tsao, Timothy Morgan, Saiju Pyarajan, Julie Lynch, Benjamin Voight, Kyong-Mi Chang
Publikováno v:
Journal of Hepatology. 77:S936
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bdd612d689e2c7d7e8461d769a333b3
https://doi.org/10.1016/s0168-8278(22)02153-5
https://doi.org/10.1016/s0168-8278(22)02153-5
Autor:
Derek Klarin, Lin Chang, Sarah E. Graham, Brooke N. Wolford, Jonathan L. Eliason, Ben Michael Brumpton, Minerva T. Garcia-Barrio, Kristian Hveem, Michael R. Mathis, Santhi K. Ganesh, Gao Wang, Wei Zhou, Maoxuan Lin, Ida Surakka, Saiju Pyarajan, Bo Yang, Dianna M. Milewicz, Jifeng Zhang, Zhenguo Wang, Michael J. Shea, Dongchuan Guo, Anne Heidi Skogholt, Karen Meekyong Kim, Chad M. Brummett, Bjørn Olav Åsvold, Tori L. Melendez, Kim A. Eagle, Bradley Crone, Poornima Devineni, Philip S. Tsao, Whitney E. Hornsby, Haocheng Lu, Y. Eugene Chen, Scott M. Damrauer, Cristen J. Willer, Tanmoy Roychowdhury, Himanshu J. Patel, Suzanne M. Leal, Anoop K Sendamarai, G. Michael Deeb, VA Million Veteran Program
Publikováno v:
Am J Hum Genet
Summary Thoracic aortic aneurysm (TAA) is characterized by dilation of the aortic root or ascending/descending aorta. TAA is a heritable disease that can be potentially life threatening. While 10%–20% of TAA cases are caused by rare, pathogenic var
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::774b58c739f2f84555c5180c22d79920
https://pubmed.ncbi.nlm.nih.gov/34265237
https://pubmed.ncbi.nlm.nih.gov/34265237
Autor:
Sudha K Iyengar, Yan V. Sun, Stephen Burgess, Nicole M Kosik, Christopher J. O'Donnell, Sonja A. Swanson, Maik Pietzner, Yunling Shi, Kyong-Mi Chang, Alexandre C. Pereira, Philip S. Tsao, Anna Gaulton, A. Patrícia Bento, Jennifer E. Huffman, Juan P Casas, Jin Zhou, Yuk-Lam Ho, Claudia Giambartolomei, Bryan R Gorman, Dennis Valentine, Inigo Barrio-Hernandez, Jing Hua Zhao, Jean C. Beckham, Elias Allara, Daniel C Posner, Kristine E. Lynch, Niklas Hagberg, Christian Lundtoft, David R. Gagnon, Rachel Ramoni, Adriana M. Hung, Lauren O Thomann, Marijana Vujkovic, Lars Rönnblom, Helene Garcon, Praveen Surendran, Liam Gaziano, Bram P. Prins, Poornima Devineni, Scott L. DuVall, Jacob Joseph, Grant D. Huang, John Danesh, Andrew R. Leach, James E. Peters, Todd L. Edwards, J. Michael Gaziano, Kelly Cho, Pedro Beltrao, Claudia Langenberg, Sumitra Muralidhar, Adam S. Butterworth, Saiju Pyarajan
Drug repurposing provides a rapid approach to meet the urgent need for therapeutics to address COVID-19. To identify therapeutic targets relevant to COVID-19, we conducted Mendelian randomization (MR) analyses, deriving genetic instruments based on t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1da248fa154d58173fd385b706c52a1f
https://doi.org/10.1101/2020.11.19.20234120
https://doi.org/10.1101/2020.11.19.20234120
Autor:
Donald E. Humphries, Tim Assimes, Yunling Shi, Joel Gelernter, John Michael Gaziano, Liem A, Mary Brophy, Karnam P, Cuiping Pan, Jie Huang, Teresa Webster, Saiju Pyarajan, Man Li, Sun-Gou Ji, Jeanette Schmidt, Timothy J. O'Leary, Jennifer Moser, Ning Sun, Grant D. Huang, Sumitra Muralidhar, Radhakrishnan L, Elizabeth R. Hauser, P.S. Tsao, Paul Hsieh, Poornima Devineni, Ronald M. Przygodzki, Christopher J. O'Donnell, Hongyu Zhao, John Concato, Haley Hunter-Zinck, Gorman Br
The Million Veteran Program (MVP), initiated by the Department of Veterans Affairs (VA), aims to collect consented biosamples from at least one million Veterans. Presently, blood samples have been collected from over 800,000 enrolled participants. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2e264d50662c6a186744fd9c7e1ae0d
https://doi.org/10.1101/2020.01.06.896613
https://doi.org/10.1101/2020.01.06.896613