Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Poornima Chalasani"'
Autor:
Pasi A. Jänne, Poornima Chalasani, Yunling Shi, Caitlin Fontes, Stacy Mach, Lynette M. Sholl, Suzanne E. Dahlberg, Marzia Capelletti, Amanda J. Redig
Supplemental Table 1: Identified NF1 variants; Supplemental Table 2: Tumors with multiple NF1 mutations include splice site, missense, nonsense, and frameshift mutations; Supplemental Table 3: KRAS mutations identified by next-generation sequencing.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ed0155314c6c80008f259cfb48551a9
https://doi.org/10.1158/1078-0432.22457816.v1
https://doi.org/10.1158/1078-0432.22457816.v1
Autor:
Andrey Belozerov, Dmitry Botvinnik, Ronald Beaudoin, Purushotham Karnam, Caitlin Fontes, Ameet Pathak, John Orechia, Mollie Ullman-Cullere, Jomol Mathew, Daniel Quinn, Yunling Shi, Padam Chhetri, James Byleckie, Camille Lakhiani, Aniket Nawani, Eddie Mei, Chetan Jawale, Sandeep Sahu, Poornima Chalasani, Elizabeth Cotter, Chetansharan Patel, Yelena Belozerova
Publikováno v:
Applied & Translational Genomics
Applied and Translational Genomics, Vol 6, Iss C, Pp 18-25 (2015)
Applied and Translational Genomics, Vol 6, Iss C, Pp 18-25 (2015)
We live in the genomic era of medicine, where a patient's genomic/molecular data is becoming increasingly important for disease diagnosis, identification of targeted therapy, and risk assessment for adverse reactions. However, decoding the genomic te
Autor:
Lynette M. Sholl, Marzia Capelletti, Poornima Chalasani, Suzanne E. Dahlberg, Amanda J. Redig, Pasi A. Jänne, Stacy L. Mach, Yunling Shi, Caitlin Fontes
Purpose: NF1 is a tumor suppressor that negatively regulates Ras signaling. NF1 mutations occur in lung cancer, but their clinical significance is unknown. We evaluated clinical and molecular characteristics of NF1 mutant lung cancers with comparison
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed1757f7ecdb58396843530e15b75606
https://europepmc.org/articles/PMC5129179/
https://europepmc.org/articles/PMC5129179/
Autor:
Feng Ding, Natalia E. Broude, Shantanu Sharma, Vadim V. Demidov, Nikolay V. Dokholyan, Poornima Chalasani
Publikováno v:
RNA. 14:1164-1173
RNA molecules with novel functions have revived interest in the accurate prediction of RNA three-dimensional (3D) structure and folding dynamics. However, existing methods are inefficient in automated 3D structure prediction. Here, we report a robust
Autor:
Carlos Witte-Hoffmann, Natalia E. Broude, Poornima Chalasani, Nikolay V. Dokholyan, Feng Ding, Yong Yu, Hung Wei Yiu, Charles R. Cantor, Vadim V. Demidov
Publikováno v:
Proceedings of the National Academy of Sciences. 103:2052-2056
Fluorescent proteins have proven to be excellent reporters and biochemical sensors with a wide range of applications. In a split form, they are not fluorescent, but their fluorescence can be restored by supplementary protein–protein or protein–nu
Autor:
Pasi A. Jänne, Amanda J. Redig, Caitlin Fontes, Suzanne E. Dahlberg, Stacy L. Mach, Yunling Shi, Poornima Chalasani, Marzia Capelletti
Publikováno v:
Journal of Clinical Oncology. 33:8022-8022
8022 Background: NF1 is a tumor suppressor that negatively regulates Ras, thus NF1 mutant tumors may also be sensitive to inhibitors of MAP kinase signaling. NF1 variants occur in lung cancer, but ...