Pigs lacking TMPRSS2 displayed fewer lung lesions and reduced inflammatory response when infected with influenza A virus.

Autor: Zanella, Giovana Ciacci, Snyder, Celeste A., Arruda, Bailey L., Whitworth, Kristin, Green, Erin, Poonooru, Ravikanth Reddy, Telugu, Bhanu P., Baker, Amy L.

Publikováno v: Frontiers in Genome Editing; 2024, p1-11, 11p

Pigs lacking TMPRSS2 displayed fewer lung lesions and reduced inflammatory response when infected with influenza A virus.

Autor: Ciacci Zanella G; Virus and Prion Research Unit, National Animal Disease Center, United States Department of Agriculture, Agricultural Research Service, Ames, IA, United States.; Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA, United States., Snyder CA; Virus and Prion Research Unit, National Animal Disease Center, United States Department of Agriculture, Agricultural Research Service, Ames, IA, United States., Arruda BL; Virus and Prion Research Unit, National Animal Disease Center, United States Department of Agriculture, Agricultural Research Service, Ames, IA, United States., Whitworth K; National Swine Resource and Research Center, University of Missouri, Columbia, MO, United States.; Division of Animal Sciences, College of Agriculture, Food and Natural Resources, University of Missouri, Columbia, MO, United States., Green E; Division of Animal Sciences, College of Agriculture, Food and Natural Resources, University of Missouri, Columbia, MO, United States., Poonooru RR; Division of Animal Sciences, College of Agriculture, Food and Natural Resources, University of Missouri, Columbia, MO, United States., Telugu BP; National Swine Resource and Research Center, University of Missouri, Columbia, MO, United States.; Division of Animal Sciences, College of Agriculture, Food and Natural Resources, University of Missouri, Columbia, MO, United States., Baker AL; Virus and Prion Research Unit, National Animal Disease Center, United States Department of Agriculture, Agricultural Research Service, Ames, IA, United States.

Publikováno v: Frontiers in genome editing [Front Genome Ed] 2024 May 31; Vol. 5, pp. 1320180. Date of Electronic Publication: 2024 May 31 (Print Publication: 2023).