Výsledky vyhledávání - "Pooneh Khoshakhlagh"

Nanoparticle structure development in the gastro‐intestinal model fluid FaSSIF mod6.5 from several phospholipids at various water content relevant for oral drug administration

Autor: Pooneh Khoshakhlagh, Thomas Nawroth, Noemi Szekely, Nadja Hellmann, Raphael Johnson, Lars Schmueser, Peter Langguth, Heinz Decker

Publikováno v: European Journal of Lipid Science and Technology. 116:1155-1166

The characteristics of intestinal model fluids were investigated at conditions, which simulate the passage from the middle to the end of the duodenum. The formation and decay of liposomes and micelles in model bile fluids were studied, because of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ac42703b89aad1f26084c42b09f54ae7
https://doi.org/10.1002/ejlt.201400066

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Amphotericin B microparticles ‘AmbiShell’ from phospholipid and gelatin: Development and investigation by combined DLS and SANS resolves the core‐shell structure

Autor: Raphael Johnson, Lars Schmueser, Nadja Hellmann, Thomas Nawroth, Noemi Szekely, Heinz Decker, Pooneh Khoshakhlagh, Peter Langguth

Publikováno v: European Journal of Lipid Science and Technology. 116:1167-1173

A novel homogenous core-shell formulation ‘AmbiShell’ of the hydrophobic antifungal polyene drug Amphotericin B was prepared from the pure drug, lecithin, and gelatin. The established ‘Hydrophilic Solubilisation Technology’ (HST) was used for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::92dfcac8ee1b9421a4266ff66ec1e2c5
https://doi.org/10.1002/ejlt.201400069

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Inhibition of Tumor Necrosis Factor and Nitrosative/Oxidative Stresses byZiziphora Clinopoides(Kahlioti); A Molecular Mechanism of Protection Against Dextran Sodium Sulfate-Induced Colitis in Mice

Autor: Akram Ranjbar, Azadeh Mohammadirad, Asieh Hoseini, Pooneh Khoshakhlagh, Mohammad Abdollahi, Noushin Amini-Shirazi, Nargues Yasa

Publikováno v: Toxicology Mechanisms and Methods. 19:183-189

Inflammatory bowel disease (IBD) is a chronic condition of the intestine with unknown etiology involving multiple immune genetic and environmental factors. The authors were interested in examining the protective effect of Ziziphora clinopoides methan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::097eda4573cc3e7e980e0ae5c4097a2f
https://doi.org/10.1080/15376510701533996

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Beneficial Effect of Phosphodiesterase-5 Inhibitor in Experimental Inflammatory Bowel Disease; Molecular Evidence for Involvement of Oxidative Stress

Autor: Mina Bahrololoumi-Shapourabadi, Bagher Minaie, Leila Ashtaral-Nakhai, Pooneh Khoshakhlagh, Azadeh Mohammadirad, Mohammad Abdollahi

Publikováno v: Toxicology Mechanisms and Methods. 17:281-288

Inflammatory bowel disease (IBD) is a common and chronic gastrointestinal disorder characterized by intestinal inflammation and mucosal tissue damage. Reactive oxygen metabolites (ROMs) play a pathogenic role in IBD. We aimed to examine the protectiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5743056095ee0c3ce266ddfd489de46b
https://doi.org/10.1080/15376510601003769

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Fasted-state simulated intestinal fluid 'FaSSIF-C', a cholesterol containing intestinal model medium for in vitro drug delivery development

Autor: Nadja Hellmann, Noemi Szekely, Pooneh Khoshakhlagh, Raphael Johnson, Thomas Nawroth, Heinz Decker, Lars Schmueser, Peter Langguth

Publikováno v: Journal of pharmaceutical sciences. 104(7)

A set of biorelevant media "fasted-state simulated intestinal fluid with cholesterol (FaSSIF-C)" for the in vitro study of intestinal drug dissolution in the duodenum was developed. These contain cholesterol at the same levels as in human bile: the c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00d6ff6b68277f20e51160630a4814a9
https://pubmed.ncbi.nlm.nih.gov/25964103

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