Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Poonam Kakade"'
Autor:
Poonam Kakade, Hina Ojha, Olawale G. Raimi, Andrew Shaw, Andrew D. Waddell, James R. Ault, Sophie Burel, Kathrin Brockmann, Atul Kumar, Mohd Syed Ahangar, Ewelina M. Krysztofinska, Thomas Macartney, Richard Bayliss, Julia C. Fitzgerald, Miratul M. K. Muqit
Publikováno v:
Open Biology, Vol 12, Iss 1 (2022)
Autosomal recessive mutations in the PINK1 gene are causal for Parkinson's disease (PD). PINK1 encodes a mitochondrial localized protein kinase that is a master-regulator of mitochondrial quality control pathways. Structural studies to date have elab
Externí odkaz:
https://doaj.org/article/676e5fcd8544472ba7c52603d7ecf995
Autor:
Andrew D. Waddell, Hina Ojha, Shalini Agarwal, Christopher J. Clarke, Ana Terriente-Felix, Houjiang Zhou, Poonam Kakade, Axel Knebel, Andrew M. Shaw, Robert Gourlay, Joby Varghese, Renata F. Soares, Rachel Toth, Thomas Macartney, Patrick A. Eyers, Nick Morrice, Richard Bayliss, Alexander J. Whitworth, Claire E. Eyers, Miratul M. K. Muqit
Loss-of-function mutations in the human PINK1 kinase (hPINK1) are causative of early-onset Parkinson’s disease (PD). Activation of hPINK1 induces phosphorylated ubiquitin to initiate removal of damaged mitochondria by autophagy. Previously we solve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e00472b151d1285b844ca753507a62
https://doi.org/10.1101/2023.03.31.534916
https://doi.org/10.1101/2023.03.31.534916
