Vitamin D supplementation compared to placebo in people with First Episode psychosis - Neuroprotection Design (DFEND): a protocol for a randomised, double-blind, placebo-controlled, parallel-group trial

Autor: Fiona Gaughran, Dominic Stringer, Michael Berk, Shubulade Smith, David Taylor, Eromona Whiskey, Sabine Landau, Robin Murray, Philip McGuire, Poonam Gardner-Sood, Gabriella Wojewodka, Simone Ciufolini, Harriet Jordan, Jessie Clarke, Lauren Allen, Amir Krivoy, Brendon Stubbs, Philippa Lowe, Maurice Arbuthnott, Shanaya Rathod, Andrew Boardman, Mudasir Firdosi, John J. McGrath

Publikováno v: Trials, Vol 21, Iss 1, Pp 1-12 (2020)

Abstract Background People experiencing their first episode of psychosis are often deficient in vitamin D. Observational studies have reported an association between low vitamin D concentrations and poorer subsequent health outcomes in psychosis. A v

Externí odkaz: https://doaj.org/article/9818ac87758f4b8d87af5d844071e6d3

Randomised controlled trial to improve health and reduce substance use in established psychosis (IMPaCT): cost-effectiveness of integrated psychosocial health promotion

Autor: Margaret Heslin, Anita Patel, Daniel Stahl, Poonam Gardner-Sood, Manyara Mushore, Shubulade Smith, Kathryn Greenwood, Oluwadamilola Onagbesan, Conan O’Brien, Catherine Fung, Ruth Ohlsen, David Hopkins, Philippa Lowe, Maurice Arbuthnot, Stan Mutatsa, Gill Todd, Anna Kolliakou, John Lally, Brendon Stubbs, Khalida Ismail, Anthony David, Robin Murray, Zerrin Atakan, Fiona Gaughran

Publikováno v: BMC Psychiatry, Vol 17, Iss 1, Pp 1-13 (2017)

Abstract Background There is mounting evidence that people with severe mental illness have unhealthy lifestyles, high rates of cardiovascular and metabolic diseases, and greater risk of early mortality. This study aimed to assess the cost-effectivene

Externí odkaz: https://doaj.org/article/5c28d4f17dec44839e4bc192dc1847f4

The Representativeness of Participants With Severe Mental Illness in a Psychosocial Clinical Trial

Autor: John Lally, Rochelle Watkins, Sarah Nash, Hitesh Shetty, Poonam Gardner-Sood, Shubulade Smith, Robin M. Murray, Fiona Gaughran

Publikováno v: Frontiers in Psychiatry, Vol 9 (2018)

Introduction: Cardiovascular morbidity and mortality are increased in severe mental illnesses (SMI). Trials of psychosocial health interventions to improve physical health in SMI, including in treatment-resistant schizophrenia, have shown some benefi

Externí odkaz: https://doaj.org/article/4a36869b988c44ebaa2b9d19805dfdb5

A health promotion intervention to improve lifestyle choices and health outcomes in people with psychosis: a research programme including the IMPaCT RCT

Autor: Brendon Stubbs, Poonam Gardner-Sood, Daniel Stahl, Anita Patel, Margaret Heslin, John Lally, Khalida Ismail, Marta Di Forti, Robin M. Murray, Anthony S. David, Philippa Lowe, Shubulade Smith, Maurice Arbuthnott, Dominic Stringer, Kathryn Greenwood, Zerrin Atakan, David Hopkins, Fiona Gaughran

Publikováno v: Programme Grants for Applied Research, Vol 8, Iss 1 (2020)
Gaughran, F, Stahl, D, Patel, A, Ismail, K, Smith, S, Greenwood, K, Atakan, Z, Gardner-Sood, P, Stringer, D, Hopkins, D, Lally, J, Di Forti, M, Stubbs, B, Lowe, P, Arbuthnott, M, Heslin, M, David, A S & Murray, R M 2020, ' A health promotion intervention to improve lifestyle choices and health outcomes in people with psychosis : a research programme including the IMPaCT RCT ', Programme Grants for Applied Research, vol. 8, no. 1 . https://doi.org/10.3310/pgfar08010

Background People with psychotic disorders have reduced life expectancy largely because of physical health problems, especially cardiovascular disease, that are complicated by the use of tobacco and cannabis. Objectives We set out to (1) chart lifest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::752e83e901ff6f1ff3fc782d8194bbde
https://doi.org/10.3310/pgfar08010

Vitamin D and clinical symptoms in First Episode Psychosis (FEP): A prospective cohort study

Autor: Robin M. Murray, Oliver D. Howes, Nidhita Singh, Fiona Gaughran, Poonam Gardner-Sood, John Lally, Brendon Stubbs, Marta Di Forti, Dominic Stringer, Anthony S. David, Shubulade Smith, Olesya Ajnakina

Publikováno v: Lally, J, Ajnakina, O, Singh, N, Gardner-Sood, P, Stubbs, B, Stringer, D, Di Forti, M, David, A S, Smith, S, Murray, R M, Howes, O D & Gaughran, F 2019, ' Vitamin D and clinical symptoms in First Episode Psychosis (FEP) : a prospective cohort study ', Schizophrenia Research, vol. 204, pp. 381-388 . https://doi.org/10.1016/j.schres.2018.08.011

BACKGROUND: There is a paucity of longitudinal research investigating vitamin D in people with early psychosis.METHOD: Vitamin D levels were measured in 168 patients (64% (n = 108) male, mean age 29.3 (9.8) years) with first episode psychosis (FEP),

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67690dfa805b0b3c1ceab591eebc614e
https://doi.org/10.1016/j.schres.2018.08.011