A COVID-19 Silver Lining—Decline in Antibiotic Resistance in Ischemic Leg Ulcers during the Pandemic: A 6-Year Retrospective Study from a Regional Tertiary Hospital (2017–2022)

Autor: Amaraporn Rerkasem, Pak Thaichana, Nuttida Bunsermvicha, Rawee Nopparatkailas, Supapong Arwon, Saranat Orrapin, Termpong Reanpang, Poon Apichartpiyakul, Saritphat Orrapin, Boonying Siribumrungwong, Nongkran Lumjuan, Kittipan Rerkasem, José G. B. Derraik

Publikováno v: Antibiotics, Vol 13, Iss 1, p 35 (2023)

Antibiotic resistance (AR) associated with chronic limb-threatening ischemia (CLTI) poses additional challenges for the management of ischemic leg ulcers, increasing the likelihood of severe outcomes. This study assessed AR prevalence in bacteria iso

Externí odkaz: https://doaj.org/article/9a5e9c5d6c1f47fc8127b9eb7301e4c1

Temperature-sensitive mutations in the putative herpes simplex virus type 1 terminase subunits pUL15 and pUL33 preclude viral DNA cleavage/packaging and interaction with pUL28 at the nonpermissive temperature.

Autor: Yang K; C5132 Veterinary Education Center, Department of Microbiology and Immunology, New York State College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA., Poon AP, Roizman B, Baines JD

Publikováno v: Journal of virology [J Virol] 2008 Jan; Vol. 82 (1), pp. 487-94. Date of Electronic Publication: 2007 Oct 03.

ICP0 and the US3 protein kinase of herpes simplex virus 1 independently block histone deacetylation to enable gene expression.

Autor: Poon AP; The Marjorie B. Kovler Viral Oncology Laboratories, University of Chicago, 910 East 58th Street, Chicago, IL 60637, USA., Gu H, Roizman B

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2006 Jun 27; Vol. 103 (26), pp. 9993-8. Date of Electronic Publication: 2006 Jun 19.

Ionizing radiation activates late herpes simplex virus 1 promoters via the p38 pathway in tumors treated with oncolytic viruses.

Autor: Mezhir JJ; Department of Surgery, University of Chicago, Chicago, IL 60637, USA., Advani SJ, Smith KD, Darga TE, Poon AP, Schmidt H, Posner MC, Roizman B, Weichselbaum RR

Publikováno v: Cancer research [Cancer Res] 2005 Oct 15; Vol. 65 (20), pp. 9479-84.

The carboxyl-terminal domain of RNA polymerase II is phosphorylated by a complex containing cdk9 and infected-cell protein 22 of herpes simplex virus 1.

Autor: Durand LO; The Marjorie B. Kovler Viral Oncology Laboratories, The University of Chicago, 910 East 58th Street, Chicago, IL 60637, USA., Advani SJ, Poon AP, Roizman B

Publikováno v: Journal of virology [J Virol] 2005 Jun; Vol. 79 (11), pp. 6757-62.