Gene Therapy for Glaucoma by Ciliary Body Aquaporin 1 Disruption Using CRISPR-Cas9

Autor: Wu, Jiahui, Bell, Oliver H., Copland, David A., Young, Alison, Pooley, John R., Maswood, Ryea, Evans, Rachel S., Khaw, Peng Tee, Ali, Robin R., Dick, Andrew D., Chu, Colin J.

Publikováno v: In Molecular Therapy 4 March 2020 28(3):820-829

Genome-Wide Identification of Basic Helix–Loop–Helix and NF-1 Motifs Underlying GR Binding Sites in Male Rat Hippocampus

Autor: Pooley, John R., Flynn, Ben P., Grøntved, Lars, Baek, Songjoon, Guertin, Michael J., Kershaw, Yvonne M., Birnie, Matthew T., Pellatt, Annie, Rivers, Caroline A., Schiltz, R. Louis, Hager, Gordon L., Lightman, Stafford L., Conway-Campbell, Becky L.

Publikováno v: Endocrinology

Glucocorticoids regulate hippocampal function in part by modulating gene expression through the glucocorticoid receptor (GR). GR binding is highly cell type specific, directed to accessible chromatin regions established during tissue differentiation.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4feb71cb47cd9137a55abadc7b9d8283
http://europepmc.org/articles/PMC5460825

Genome-wide identification of basic helix-loop-helix and NF-1 motifs underlying GR binding sites in male rat hippocampus

Autor: Pooley, John R, Flynn, Ben P, Grøntved, Lars, Baek, Songjoon, Guertin, Michael J, Kershaw, Yvonne M, Birnie, Matthew T, Pellatt, Annie, Rivers, Caroline A, Schiltz, R Louis, Hager, Gordon L, Lightman, Stafford L, Conway-Campbell, Becky L

Publikováno v: Pooley, J R, Flynn, B P, Grøntved, L, Baek, S, Guertin, M J, Kershaw, Y M, Birnie, M T, Pellatt, A, Rivers, C A, Schiltz, R L, Hager, G L, Lightman, S L & Conway-Campbell, B L 2017, ' Genome-wide identification of basic helix-loop-helix and NF-1 motifs underlying GR binding sites in male rat hippocampus ', Endocrinology, vol. 158, no. 5, pp. 1486-1501 . https://doi.org/10.1210/en.2016-1929
Pooley, J R, Flynn, B P, Grøntved, L, Baek, S, Guertin, M J, Kershaw, Y M, Birnie, M T, Pellatt, A, Rivers, C A, Schiltz, R L, Hager, G L, Lightman, S L & Conway-Campbell, B L 2017, ' Genome-wide identification of basic helix-loop helix and NF-1 motifs underlying GR binding sites in male rat hippocampus ', Endocrinology, vol. 158, no. 5, pp. 1486–1501 . https://doi.org/10.1210/en.2016-1929

Glucocorticoids regulate hippocampal function in part by modulating gene expression through the glucocorticoid receptor (GR). GR binding is highly cell type specific, directed to accessible chromatin regions established during tissue differentiation.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::63f35b2c1671c9aa8816921833909f23
https://findresearcher.sdu.dk:8443/ws/files/137358673/Genome_Wide_Identification_of_Basic_Helix_Loop_Helix_and_NF_1_Motifs_Underlying_GR_Binding_Sites_in_Male_Rat_Hippocampus.pdf

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