Minimally modified human blood coagulation factor X to bypass direct factor Xa inhibitors.

Autor: Schreuder M; Department of Internal Medicine, Division of Thrombosis and Hemostasis, Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, The Netherlands., Jourdi G; Assistance publique - Hôpitaux de Paris (AH-HP) Centre, Service d'hématologie biologique, Hôpital Cochin, Paris, France; Innovative Therapies in Haemostasis, Institut national de la santé et de la recherche médicale (INSERM) U1140, Université Paris Cité, Paris, France; Assistance publique - Hôpitaux de Paris (AH-HP) Nord, Service d'hématologie biologique, Hôpital Lariboisière, Paris, France., Veizaj D; Department of Internal Medicine, Division of Thrombosis and Hemostasis, Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, The Netherlands., Poole DA 3rd; Amsterdam Institute of Molecular and Life Sciences (AIMMS), Division of Molecular and Computational Toxicology, Department of Chemistry and Pharmaceutical Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Cheung KL; Department of Internal Medicine, Division of Thrombosis and Hemostasis, Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, The Netherlands., Poenou G; Department of Internal Medicine, Division of Thrombosis and Hemostasis, Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, The Netherlands; Innovative Therapies in Haemostasis, Institut national de la santé et de la recherche médicale (INSERM) U1140, Université Paris Cité, Paris, France., Verhoef D; Department of Internal Medicine, Division of Thrombosis and Hemostasis, Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, The Netherlands; VarmX B.V., Leiden, The Netherlands., Thomassen S; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands., Janssen LFH; Amsterdam Institute of Molecular and Life Sciences (AIMMS), Division of Molecular and Computational Toxicology, Department of Chemistry and Pharmaceutical Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Stepanian A; Assistance publique - Hôpitaux de Paris (AH-HP) Nord, Service d'hématologie biologique, Hôpital Lariboisière, Paris, France; EA3518 Institut Universitaire d'Hématologie, Hôpital Saint Louis, Paris-Diderot, Paris, France., Hackeng TM; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands., Gaussem P; Innovative Therapies in Haemostasis, Institut national de la santé et de la recherche médicale (INSERM) U1140, Université Paris Cité, Paris, France; Assistance publique - Hôpitaux de Paris (AP-HP) Centre, Service d'hématologie biologique, Hôpital Européen Georges Pompidou, Paris, France., Reitsma PH; Department of Internal Medicine, Division of Thrombosis and Hemostasis, Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, The Netherlands; VarmX B.V., Leiden, The Netherlands., Geerke DP; Amsterdam Institute of Molecular and Life Sciences (AIMMS), Division of Molecular and Computational Toxicology, Department of Chemistry and Pharmaceutical Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Siguret V; Innovative Therapies in Haemostasis, Institut national de la santé et de la recherche médicale (INSERM) U1140, Université Paris Cité, Paris, France; Assistance publique - Hôpitaux de Paris (AH-HP) Nord, Service d'hématologie biologique, Hôpital Lariboisière, Paris, France., Bos MHA; Department of Internal Medicine, Division of Thrombosis and Hemostasis, Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, The Netherlands. Electronic address: M.H.A.Bos@lumc.nl.

Publikováno v: Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2024 Aug; Vol. 22 (8), pp. 2211-2226. Date of Electronic Publication: 2024 May 09.

Broadening the catalytic region from the cavity to windows by M 6 L 12 nanospheres in cyclizations.

Autor: Xu M; State Key Laboratory of Fine Chemicals, Dalian University of Technology Dalian 116024 P. R. China xjing@dlut.edu.cn cyduan@dlut.edu.cn., Sun B; Homogeneous, Supramolecular and Bio-Inspired Catalysis, Van't Hoff Institute for Molecular Sciences, University of Amsterdam Science Park 904 Amsterdam 1098 XH The Netherlands j.n.h.reek@uva.nl., Poole DA 3rd; Homogeneous, Supramolecular and Bio-Inspired Catalysis, Van't Hoff Institute for Molecular Sciences, University of Amsterdam Science Park 904 Amsterdam 1098 XH The Netherlands j.n.h.reek@uva.nl., Bobylev EO; Homogeneous, Supramolecular and Bio-Inspired Catalysis, Van't Hoff Institute for Molecular Sciences, University of Amsterdam Science Park 904 Amsterdam 1098 XH The Netherlands j.n.h.reek@uva.nl., Jing X; State Key Laboratory of Fine Chemicals, Dalian University of Technology Dalian 116024 P. R. China xjing@dlut.edu.cn cyduan@dlut.edu.cn., Wu J; State Key Laboratory of Fine Chemicals, Dalian University of Technology Dalian 116024 P. R. China xjing@dlut.edu.cn cyduan@dlut.edu.cn., He C; State Key Laboratory of Fine Chemicals, Dalian University of Technology Dalian 116024 P. R. China xjing@dlut.edu.cn cyduan@dlut.edu.cn., Duan C; State Key Laboratory of Fine Chemicals, Dalian University of Technology Dalian 116024 P. R. China xjing@dlut.edu.cn cyduan@dlut.edu.cn., Reek JNH; Homogeneous, Supramolecular and Bio-Inspired Catalysis, Van't Hoff Institute for Molecular Sciences, University of Amsterdam Science Park 904 Amsterdam 1098 XH The Netherlands j.n.h.reek@uva.nl.

Publikováno v: Chemical science [Chem Sci] 2023 Sep 26; Vol. 14 (42), pp. 11699-11707. Date of Electronic Publication: 2023 Sep 26 (Print Publication: 2023).

In vivo biodistribution of kinetically stable Pt 2 L 4 nanospheres that show anti-cancer activity.

Autor: Bobylev EO; van 't Hoff Institute for Molecular Sciences, University of Amsterdam Science Park 904 1098 XH Amsterdam The Netherlands j.n.h.reek@uva.nl., Knol RA; Dept. of Supramolecular & Biomaterials Chemistry, Leiden Institute of Chemistry, Leiden University P.O. Box 9502 2300 RA Leiden The Netherlands., Mathew S; van 't Hoff Institute for Molecular Sciences, University of Amsterdam Science Park 904 1098 XH Amsterdam The Netherlands j.n.h.reek@uva.nl., Poole DA 3rd; van 't Hoff Institute for Molecular Sciences, University of Amsterdam Science Park 904 1098 XH Amsterdam The Netherlands j.n.h.reek@uva.nl., Kotsogianni I; Biological Chemistry Group, Institute of Biology Leiden, Leiden University 2333 BE Leiden The Netherlands., Martin NI; Biological Chemistry Group, Institute of Biology Leiden, Leiden University 2333 BE Leiden The Netherlands., de Bruin B; van 't Hoff Institute for Molecular Sciences, University of Amsterdam Science Park 904 1098 XH Amsterdam The Netherlands j.n.h.reek@uva.nl., Kros A; Dept. of Supramolecular & Biomaterials Chemistry, Leiden Institute of Chemistry, Leiden University P.O. Box 9502 2300 RA Leiden The Netherlands., Reek JNH; van 't Hoff Institute for Molecular Sciences, University of Amsterdam Science Park 904 1098 XH Amsterdam The Netherlands j.n.h.reek@uva.nl.

Publikováno v: Chemical science [Chem Sci] 2023 May 22; Vol. 14 (25), pp. 6943-6952. Date of Electronic Publication: 2023 May 22 (Print Publication: 2023).

Exposing Mechanisms for Defect Clearance in Supramolecular Self-Assembly: Palladium-Pyridine Coordination Revisited.

Autor: Poole DA 3rd; Homogeneous, Supramolecular, and Bioinspired Catalysis group, van't Hoff Institute for Molecular Science (HIMS), University of Amsterdam (UvA), Science Park 904, 1098 XH Amsterdam, The Netherlands., Bobylev EO; Homogeneous, Supramolecular, and Bioinspired Catalysis group, van't Hoff Institute for Molecular Science (HIMS), University of Amsterdam (UvA), Science Park 904, 1098 XH Amsterdam, The Netherlands., de Bruin B; Homogeneous, Supramolecular, and Bioinspired Catalysis group, van't Hoff Institute for Molecular Science (HIMS), University of Amsterdam (UvA), Science Park 904, 1098 XH Amsterdam, The Netherlands., Mathew S; Homogeneous, Supramolecular, and Bioinspired Catalysis group, van't Hoff Institute for Molecular Science (HIMS), University of Amsterdam (UvA), Science Park 904, 1098 XH Amsterdam, The Netherlands., Reek JNH; Homogeneous, Supramolecular, and Bioinspired Catalysis group, van't Hoff Institute for Molecular Science (HIMS), University of Amsterdam (UvA), Science Park 904, 1098 XH Amsterdam, The Netherlands.

Publikováno v: Inorganic chemistry [Inorg Chem] 2023 Apr 10; Vol. 62 (14), pp. 5458-5467. Date of Electronic Publication: 2023 Mar 24.

M 6 L 12 Nanospheres with Multiple C 70 Binding Sites for ¹ O 2 Formation in Organic and Aqueous Media.

Autor: Bobylev EO; van 't Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098 XH Amsterdam The Netherlands., Poole DA 3rd; van 't Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098 XH Amsterdam The Netherlands., de Bruin B; van 't Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098 XH Amsterdam The Netherlands., Reek JNH; van 't Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098 XH Amsterdam The Netherlands.

Publikováno v: Journal of the American Chemical Society [J Am Chem Soc] 2022 Aug 31; Vol. 144 (34), pp. 15633-15642. Date of Electronic Publication: 2022 Aug 17.