Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Pooja Teotia"'
Publikováno v:
Bio-Protocol, Vol 7, Iss 7 (2017)
In glaucoma, the output neurons of the retina, the retinal ganglion cells (RGCs), progressively degenerate, leading to irreversible blindness (Ahram et al., 2015). The ex vivo stem cell method to replace degenerated RGCs remains a potentially viable
Externí odkaz:
https://doaj.org/article/3a2f1284029a46d5a4631c4e166dd4b5
Publikováno v:
Stem Cells (Dayton, Ohio)
Glaucoma is characterized by a progressive degeneration of retinal ganglion cells (RGCs), leading to irreversible vision loss. Currently, there is no effective treatment for RGC degeneration. We used a disease‐in‐a‐dish stem cell model to exami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d16a3b16767e86841f7c15369e436f9
http://europepmc.org/articles/PMC7586941
http://europepmc.org/articles/PMC7586941
Publikováno v:
Developmental Biology. 450:90-100
In the developing central nervous system, including its simple and accessible model retina, neurogenesis is followed by gliogenesis. However, the mechanism underlying the neurogliogenic switch remains poorly understood despite the identification of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf779eed41e3b0d73c1f787edc041227
https://doi.org/10.1016/j.ydbio.2019.03.013
https://doi.org/10.1016/j.ydbio.2019.03.013
Autor:
Pooja Teotia, R. Rand Allingham, Christopher S. Wichman, Michael A. Hauser, Matthew J. Van Hook, Iqbal Ahmad
Publikováno v:
Stem Cells. 35:2239-2252
Glaucoma represents a group of multifactorial diseases with a unifying pathology of progressive retinal ganglion cell (RGC) degeneration, causing irreversible vision loss. To test the hypothesis that RGCs are intrinsically vulnerable in glaucoma, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8adf692211dd726493534bcf270f6ad3
https://doi.org/10.1002/stem.2675
https://doi.org/10.1002/stem.2675
Publikováno v:
Progress in retinal and eye research. 76
Degeneration of specific retinal neurons in diseases like glaucoma, age-related macular degeneration, and retinitis pigmentosa is the leading cause of irreversible blindness. Currently, there is no therapy to modify the disease-associated degenerativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e0d202810ff54e40d31b5b7256615ed
https://pubmed.ncbi.nlm.nih.gov/31843569
https://pubmed.ncbi.nlm.nih.gov/31843569
Publikováno v:
Development
The poor axon regeneration in the central nervous system (CNS) often leads to permanent functional deficit following disease or injury. For example, degeneration of retinal ganglion cell (RGC) axons in glaucoma leads to irreversible loss of vision. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6e332036175379e7d1c970223f8e35a
https://pubmed.ncbi.nlm.nih.gov/31273087
https://pubmed.ncbi.nlm.nih.gov/31273087
Publikováno v:
Developmental biology. 440(2)
In the developing central nervous system (CNS) the majority of neurons are born before the generation of glia. Emerging evidence implicates heterochronic gene, Lin28 in the temporal switch between two distinct lineages. However, the respective contri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e873b73365653084f5f37f54f4039f0
https://pubmed.ncbi.nlm.nih.gov/29758178
https://pubmed.ncbi.nlm.nih.gov/29758178
Autor:
Pooja Teotia, Raghu R. Krishnamoorthy, Iqbal Ahmad, Sowmya Parameswaran, John C. Morrison, Carol B. Toris, Shashank M. Dravid, Fang Qiu
Publikováno v:
Stem Cells. 33:1743-1758
Glaucoma, where the retinal ganglion cells (RGCs) carrying the visual signals from the retina to the visual centers in the brain are progressively lost, is the most common cause of irreversible blindness. The management approaches, whether surgical,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47df0ff8c40afb3eee24649467008b9d
https://doi.org/10.1002/stem.1987
https://doi.org/10.1002/stem.1987
In glaucoma, the output neurons of the retina, the retinal ganglion cells (RGCs), progressively degenerate, leading to irreversible blindness (Ahram et al., 2015). The ex vivo stem cell method to replace degenerated RGCs remains a potentially viable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4643510f8d86e41dce2eea1c23405b8c
https://europepmc.org/articles/PMC5484165/
https://europepmc.org/articles/PMC5484165/
Autor:
Iqbal Ahmad, Shashank M. Dravid, John C. Morrison, Fang Qiu, Angie Rizzino, Pooja Teotia, Matthew J. Van Hook, Divyan Chopra
Glaucoma is a complex group of diseases wherein a selective degeneration of retinal ganglion cells (RGCs) leads to irreversible loss of vision. A comprehensive approach to glaucomatous RGC degeneration may include stem cells to functionally replace d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbe8dc6340b35dabf254a080343c5278
https://europepmc.org/articles/PMC5330843/
https://europepmc.org/articles/PMC5330843/