Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Pooja Gangras"'
Autor:
Pooja Gangras, Thomas L Gallagher, Michael A Parthun, Zhongxia Yi, Robert D Patton, Kiel T Tietz, Natalie C Deans, Ralf Bundschuh, Sharon L Amacher, Guramrit Singh
Publikováno v:
PLoS Genetics, Vol 16, Iss 6, p e1008830 (2020)
Many post-transcriptional mechanisms operate via mRNA 3'UTRs to regulate protein expression, and such controls are crucial for development. We show that homozygous mutations in two zebrafish exon junction complex (EJC) core genes rbm8a and magoh lead
Externí odkaz:
https://doaj.org/article/71589bc5dee24425bea29fa9804837ca
Autor:
Pooja Gangras, Valentina Gelfanova, Graham D. Williams, Samuel K. Handelman, Ryan M. Smith, Marjoke F. Debets
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 23; Pages: 15062
The SH-SY5Y neuroblastoma cells are a widely used in vitro model approximating neurons for testing the target engagement of therapeutics designed for neurodegenerative diseases and pain disorders. However, their potential as a model for receptor-medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05bbf2a8543dd3bd43628206a3cec03e
Autor:
Pooja Gangras, Aditi Merchant
Publikováno v:
PROTEOMICS. 22:2200002
Cell surface proteins form a major fraction of the druggable proteome and can be used for tissue-specific delivery of oligonucleotide/cell-based therapeutics. Surface protein isoforms are regulated by alternative splicing, which drives subcellular lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d65bbdcce17cdce1b736f76a1a2bc5
https://doi.org/10.1002/pmic.202200002
https://doi.org/10.1002/pmic.202200002
Autor:
Ralf Bundschuh, Robert D. Patton, Guramrit Singh, Michael A. Parthun, Sharon L. Amacher, Natalie C. Deans, Thomas L. Gallagher, Pooja Gangras, Kiel T. Tietz, Zhongxia Yi
Publikováno v:
PLoS Genetics, Vol 16, Iss 6, p e1008830 (2020)
PLoS Genetics
PLoS Genetics
Many post-transcriptional mechanisms operate via mRNA 3′UTRs to regulate protein expression, and such controls are crucial for development. We show that homozygous mutations in two zebrafish exon junction complex (EJC) core genes rbm8a and magoh le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3b183666a7900de2e5302e312910e81
https://doaj.org/article/71589bc5dee24425bea29fa9804837ca
https://doaj.org/article/71589bc5dee24425bea29fa9804837ca
Publikováno v:
J Vis Exp
RNA immunoprecipitation in tandem (RIPiT) is a method for enriching RNA footprints of a pair of proteins within an RNA:protein (RNP) complex. RIPiT employs two purification steps. First, immunoprecipitation of a tagged RNP subunit is followed by mild
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97d0c11f00609df2b8663e842072a088
https://europepmc.org/articles/PMC6697088/
https://europepmc.org/articles/PMC6697088/
Autor:
Kiel T. Tietz, Ralf Bundschuh, Robert D. Patton, Pooja Gangras, Parthun Ma, Guramrit Singh, Natalie C. Deans, Thomas L. Gallagher, Sharon L. Amacher, Zhongxia Yi
The Exon Junction Complex (EJC) regulates many steps in post-transcriptional gene expression and is essential for cellular function and organismal development; however, EJC-regulated genes and genetic pathways during development remain largely unknow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deaf207f212de86627df4d8e4d56ea7f
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1680
Argonaute proteins (AGOs) are loaded with small RNAs as guides to recognize target mRNAs. Since the target specificity heavily depends on the base complementarity between two strands, it is important to identify small guide and long target RNAs bound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::72af8de6a15bb5ef40f621ceafbb4388
https://pubmed.ncbi.nlm.nih.gov/29030838
https://pubmed.ncbi.nlm.nih.gov/29030838
Publikováno v:
Methods in Molecular Biology ISBN: 9781493973385
Argonaute proteins (AGOs) are loaded with small RNAs as guides to recognize target mRNAs. Since the target specificity heavily depends on the base complementarity between two strands, it is important to identify small guide and long target RNAs bound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8035be80cbb64daa5b2f4a88e2558045
https://doi.org/10.1007/978-1-4939-7339-2_1
https://doi.org/10.1007/978-1-4939-7339-2_1
Publikováno v:
WIREs RNA. 8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d0509282923c9cee0f2c2e56555061c
https://doi.org/10.1002/wrna.1425
https://doi.org/10.1002/wrna.1425
Publikováno v:
Wiley interdisciplinary reviews. RNA. 8(3)
During messenger RNA (mRNA) biogenesis and processing in the nucleus, many proteins are imprinted on mRNAs assembling them into messenger ribonucleoproteins (mRNPs). Some of these proteins remain stably bound within mRNPs and have a long-lasting impa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7037e2689d10e1f73c313a93053fbd1
https://pubmed.ncbi.nlm.nih.gov/28008720
https://pubmed.ncbi.nlm.nih.gov/28008720