Výsledky vyhledávání - "Pooja Bhadbhade"

Akademický článek

Erythrocyte Folyl Polyglutamate Synthetase Activity Profiling as a Potential Tool for the Prediction of Methotrexate Efficacy and Toxicity in Rheumatoid Arthritis

Autor: Amar Kumar, Mudassar Iqbal Arain, Pooja Bhadbhade, Ryan Funk

Publikováno v: Future Pharmacology, Vol 3, Iss 4, Pp 819-833 (2023)

Methotrexate (MTX) is the cornerstone of therapy in the treatment of rheumatoid arthritis (RA). However, its efficacy and toxicity are variable and remain unpredictable. Interindividual variation in the metabolism of MTX by the enzyme folyl polygluta

Externí odkaz: https://doaj.org/article/cd7edce8167043e5932148d7264c9899

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Akademický článek

Plasma Metabolome Normalization in Rheumatoid Arthritis Following Initiation of Methotrexate and the Identification of Metabolic Biomarkers of Efficacy

Autor: Matthew R. Medcalf, Pooja Bhadbhade, Ted R. Mikuls, James R. O’Dell, Rebekah L. Gundry, Ryan S. Funk

Publikováno v: Metabolites, Vol 11, Iss 12, p 824 (2021)

Methotrexate (MTX) efficacy in the treatment of rheumatoid arthritis (RA) is variable and unpredictable, resulting in a need to identify biomarkers to guide drug therapy. This study evaluates changes in the plasma metabolome associated with response

Externí odkaz: https://doaj.org/article/a65b59be9dd14d04a4415b95ee3d7621

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Plasma Metabolomic Profiling as a Tool to Identify Predictive Biomarkers of Methotrexate Efficacy in Rheumatoid Arthritis

Autor: Matthew R. Medcalf, Leonidas E. Bantis, Peng Shi, Pooja Bhadbhade, Rebekah L. Gundry, Ted R. Mikuls, Bryant R. England, James R. O'Dell, Ryan S. Funk

Publikováno v: SSRN Electronic Journal.

Methotrexate (MTX) remains the first-choice disease-modifying therapy in rheumatoid arthritis (RA). However, clinical response is variable, and no reliable predictive biomarkers of efficacy currently exist. In this study, plasma metabolomic profiling

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5d5a9477ff190ad9d7da942ecf3ea37
https://doi.org/10.2139/ssrn.4084764

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Acral vascular syndrome during an immune checkpoint inhibitor

Autor: Patrick O'Connor, Raquele Laury, Pooja Bhadbhade, Qamar Khan, Stephen Williamson

Publikováno v: BMJ Case Rep

Immune checkpoint inhibitors, including antiprogrammed death cell protein 1 (anti-PD-1) and anti cytotoxic T-lymphocyte-associated protein 4 (anti-CTLA-4), have been associated with a range of autoimmune-related side effects since their introduction

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05f531bd862f91f12a089951faa5e7fc
https://europepmc.org/articles/PMC7239533/

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