Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Pooja, Panwalkar"'
Autor:
Harish Shrikrishna Bharambe, Raikamal Paul, Pooja Panwalkar, Rakesh Jalali, Epari Sridhar, Tejpal Gupta, Aliasgar Moiyadi, Prakash Shetty, Sadaf Kazi, Akash Deogharkar, Shalaka Masurkar, Kedar Yogi, Ratika Kunder, Nikhil Gadewal, Atul Goel, Naina Goel, Girish Chinnaswamy, Vijay Ramaswamy, Neelam Vishwanath Shirsat
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-16 (2019)
Abstract Genome-wide expression profiling studies have identified four core molecular subgroups of medulloblastoma: WNT, SHH, Group 3 and Group 4. Molecular markers are necessary for accurate risk stratification in the non-WNT subgroups due to the un
Externí odkaz:
https://doaj.org/article/aef8469f83e742e0adb6de2d5a4827ff
Autor:
Alexander R. Judkins, Jared Shows, Kyle S. Smith, Pooja Panwalkar, Sriram Venneti, Ashley Margol, Daniel Martinez, Chan Chung, Derek Dang, Jill Bayliss, Mike Adam, Leo Mascarenhas, Paul Le, Annie Huang, Drew Pratt, S. Steven Potter, Bruce R. Pawel, Paul A. Northcott
Publikováno v:
Neuro-Oncology. 22:785-796
Background Rhabdoid tumors (RTs) arise within (atypical teratoid/rhabdoid tumor [AT/RT]) or outside the brain (extra [e]CNS-RT) and are driven mainly by inactivation of the SWItch/sucrose nonfermentable (SWI/SNF) complex subunit SWI/SNF-related matri
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2423
MicroRNA s are small RNA molecules that regulate gene expression by binding to the 3' untranslated region of the mRNA of their target genes. MicroRNA expression is altered in medulloblastoma as compared to the normal brain and this alteration is ofte
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2423
MicroRNA s regulate gene expression by binding to the 3'untranslated region (UTR) of the mRNA of their target genes. Identification of microRNA target genes enables the determination of their functional role in the cells. A single microRNA can target
Publikováno v:
Methods in Molecular Biology ISBN: 9781071619513
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1647796a832ec413cf65bb900179a2bc
https://doi.org/10.1007/978-1-0716-1952-0_5
https://doi.org/10.1007/978-1-0716-1952-0_5
Publikováno v:
Methods in Molecular Biology ISBN: 9781071619513
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc0c6ad5528bb59e78cadf2c4eaa485d
https://doi.org/10.1007/978-1-0716-1952-0_3
https://doi.org/10.1007/978-1-0716-1952-0_3
Autor:
Jill Bayliss, Carl Koschmann, Chris Jones, Mariarita Santi, Nada Jabado, Daniel R. Wahl, Pooja Panwalkar, Anand Shankar, Viveka Nand Yadav, Siva Kumar Natarajan, Alexander R. Judkins, Arul M. Chinnaiyan, Amer Ghali, Selin Jessa, Tingting Qin, Stefan Sweha, Chan Chung, Marcin Cieslik, Drew Pratt, Kari Wilder-Romans, Visweswaran Ravikumar, Daniel Martinez, Suzanne J. Baker, Sriram Venneti, Timothy N. Phoenix, Andrew J. Scott, Matthew Pun, Alan L. Mackay, Arvind Rao, Claudia L. Kleinman
Publikováno v:
Sci Transl Med
High-grade gliomas with arginine or valine substitutions of the histone H3.3 glycine-34 residue (H3.3G34R/V) carry a dismal prognosis, and current treatments, including radiotherapy and chemotherapy, are not curative. Because H3.3G34R/V mutations rep
Autor:
Arul M. Chinnaiyan, Derek Dang, Nicholas K. Foreman, Jill Bayliss, Karin M. Muraszko, Fusheng Yang, Martin P. Ogrodzinski, Sriram Venneti, Debra Hawes, Li Jiang, Siva Kumar Natarajan, Andrew M. Donson, Drew Pratt, Stefan Sweha, Javad Nazarian, Chan Chung, Benita Tamrazi, Christopher Dunham, Hugh J. L. Garton, Joanna J. Phillips, Jason Heth, Sophia Y. Lunt, Deepak Nagrath, Brendan Mullan, Marcin Cieslik, Jin Heon, Marcel Kool, Stefan Bluml, Chao Lu, Abhinav Achreja, Andrey Korshunov, C. David Allis, Benjamin R. Sabari, Miriam Bornhorst, Matthew Pun, Juliette Hukin, Pooja Panwalkar, Olamide Animasahun, Andrea Griesinger, Stefan M. Pfister, Richard J. Gilbertson, Mariella G. Filbin, Alexander R. Judkins, Stephen Yip, Carl Koschmann
Publikováno v:
Sci Transl Med
Science translational medicine, vol 13, iss 614
Science translational medicine, vol 13, iss 614
Childhood posterior fossa group A ependymomas (PFAs) have limited treatment options and bear dismal prognoses compared to group B ependymomas (PFBs). PFAs overexpress the oncohistone-like protein EZHIP (enhancer of Zeste homologs inhibitory protein),
Autor:
Raikamal Paul, Tejpal Gupta, Rakesh Jalali, Sadaf Kazi, Kedar Yogi, Nikhil Gadewal, Naina Goel, Ratika Kunder, Aliasgar Moiyadi, Neelam Shirsat, Girish Chinnaswamy, Atul Goel, Akash Deogharkar, Epari Sridhar, Prakash Shetty, Pooja Panwalkar, Harish Shrikrishna Bharambe, Shalaka Masurkar, Vijay Ramaswamy
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-16 (2019)
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-16 (2019)
Genome-wide expression profiling studies have identified four core molecular subgroups of medulloblastoma: WNT, SHH, Group 3 and Group 4. Molecular markers are necessary for accurate risk stratification in the non-WNT subgroups due to the underlying
Autor:
Jill Bayliss, Ho-Joon Lee, Daniel Wahl, Fusheng Yang, Carl Koschmann, Arul M. Chinnaiyan, Stefan Bluml, Pooja Panwalkar, Sriram Venneti, Chan Chung, Alexander R. Judkins, Tingting Qin, Benita Tamrazi, Stefan Sweha, Marcin Cieslik, Mengrou Shan, Viveka Nand Yadav, Costas A. Lyssiotis, Adam Banda, Debra Hawes, Christian K. Werner, Drew Pratt
Publikováno v:
Cancer Research. 80:PR02-PR02
H3K27M-midline gliomas are fatal tumors that mainly harbor H3.3K27M mutations resulting in global H3K27me3 reduction that impacts neuroglial-differentiation. However, the exact mechanisms by which H3.3K27M mutations promote cancer are poorly understo