Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Pontus Aspenström"'
Autor:
Pontus Aspenström
Publikováno v:
Cells, Vol 13, Iss 7, p 647 (2024)
Miro GTPases are key components in the machinery responsible for transporting mitochondria and peroxisomes along microtubules, and also play important roles in regulating calcium homeostasis and organizing contact sites between mitochondria and the e
Externí odkaz:
https://doaj.org/article/eecfdbd0f33242bf914beb4798dad2f8
Autor:
Shixing Zheng, Xiaoxia Wang, Liudmila Matskova, Xiaoying Zhou, Zhe Zhang, Elena Kashuba, Ingemar Ernberg, Pontus Aspenström
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Loss of cell–cell adhesions is the indispensable first step for cancer cells to depart from the primary tumor mass to metastasize. Metastasis suppressor 1 (MTSS1) is frequently lost in metastatic tissues, correlating to advanced tumor stages and po
Externí odkaz:
https://doaj.org/article/70fa9a23d1fc40daac55a00e6fb7ec38
Autor:
Soumitra Mohanty, Witchuda Kamolvit, Andrea Scheffschick, Anneli Björklund, Jonas Tovi, Alexander Espinosa, Kerstin Brismar, Thomas Nyström, Jens M. Schröder, Claes-Göran Östenson, Pontus Aspenström, Hanna Brauner, Annelie Brauner
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Patients with diabetes have an increased susceptibility to infections. Here the authors show that high glucose impairs innate immunity through reduced levels of the antimicrobial peptide psoriasin and impaired epithelial barrier function, resulting i
Externí odkaz:
https://doaj.org/article/ea03a48fa5854868a7989405e31a4087
Autor:
Maureen Keller, Magdalena Blom, Lei Liu Conze, Min Guo, Daniel Hägerstrand, Pontus Aspenström
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Glioblastoma is a highly aggressive brain tumor with poor patient prognosis. Treatment outcomes remain limited, partly due to intratumoral heterogeneity and the invasive nature of the tumors. Glioblastoma cells invade and spread into the sur
Externí odkaz:
https://doaj.org/article/236901c1439f46d8b3eb442e09e18306
Autor:
Pontus Aspenström
Publikováno v:
Cancers, Vol 14, Iss 8, p 1961 (2022)
The RHO GTPases comprise a subfamily within the RAS superfamily of small GTP-hydrolyzing enzymes and have primarily been ascribed roles in regulation of cytoskeletal dynamics in eukaryotic cells. An oncogenic role for the RHO GTPases has been disrega
Externí odkaz:
https://doaj.org/article/3d6007724b6a420e8ecd6012132dbcb3
Autor:
Joman Javadi, Ghazal Heidari-Hamedani, Angelika Schmalzl, Tünde Szatmári, Muzaffer Metintas, Pontus Aspenström, Anders Hjerpe, Katalin Dobra
Publikováno v:
Cancers, Vol 13, Iss 4, p 655 (2021)
Malignant mesothelioma (MM) is an aggressive tumor of the serosal cavities. Angiogenesis is important for mesothelioma progression, but so far, anti-angiogenic agents have not improved patient survival. Our hypothesis is that better understanding of
Externí odkaz:
https://doaj.org/article/d3e07f94341a40b69cead75cbf334744
Publikováno v:
Cancers, Vol 13, Iss 4, p 685 (2021)
Malignant mesothelioma (MM) is a rare but highly aggressive cancer that primarily originates from the pleura, peritoneum or pericardium. There is a well-established link between asbestos exposure and progression of MM. Direct invasion of the surround
Externí odkaz:
https://doaj.org/article/4e0c1fcbedfa4f309b6d9bd5a1a6995d
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180810 (2017)
Vitamin D deficiency is a common health problem with consequences not limited to bone and calcium hemostasis. Low levels have also been linked to tuberculosis and other respiratory infections as well as autoimmune diseases. We have previously shown t
Externí odkaz:
https://doaj.org/article/89d7e0339cd54ab7920c3746c2d1c00b
Autor:
Pontus Aspenström
Publikováno v:
Cells, Vol 8, Iss 7, p 759 (2019)
The Rho GTPases comprise a subfamily of the Ras superfamily of small GTPases. Their importance in regulation of cell morphology and cell migration is well characterized. According to the prevailing paradigm, Cdc42 regulates the formation of filopodia
Externí odkaz:
https://doaj.org/article/8e659fef8e4a4ca48006291b0be04227
Autor:
Pontus Aspenström
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 12, p 3949 (2018)
Involvement of Rho GTPases in cancer has been a matter of debate since the identification of the first members of this branch of the Ras superfamily of small GTPases. The Rho GTPases were ascribed important roles in the cell, although these were rest
Externí odkaz:
https://doaj.org/article/85a8aad6a53249df87d861efb385e2e0